Clinical trials: Malignant Nervous System Neoplasm
Cerebellar Neoplasm
Impact of Cerebellar Mass Resection on Pain Processing
The purpose of the study is to evaluate how cerebellar resection surgery may affect pain sensation and the way the brain "reads" pain signals.
- Trial name
- NCT02261649
- Testing
- Medoc Advanced Medical Systems PATHWAY Model ATS, Cold water bath, MRI scanner
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Glioblastoma, Low Grade Glioma
Mind-Body Intervention in Glioma Couples
This trial studies how well a couple-based mind body program works in improving spiritual, psychosocial, and physical quality of life in patients with high or low grade glioma or tumors that have spread to the brain and their…
- Conditions
- Glioblastoma, Low Grade Glioma, Malignant Glioma, Metastatic Malignant Neoplasm in the Brain
- Trial name
- NCT03244995
- Testing
- Mind-Body Intervention Procedure, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Central Nervous System Sarcoma, Ependymoma
StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord
This phase I trial studies the side effects of a silicone topical wound dressing (StrataXRT) and to see how well it works in preventing radiation dermatitis (skin burns and side effects caused by radiation) in pediatric patients…
- Conditions
- Central Nervous System Sarcoma, Ependymoma, Glioma, Malignant Intracranial Germ Cell Tumor
- Trial name
- NCT03990597
- Testing
- Questionnaire Administration, Wound Dressing Material
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Individuals Aged 60 and Over, Individuals Who Are Physically and Mentally Suitable to Practice Pranayama Breathing Technique
Effects of Pranayama Breathing Technique on Stress Level, Sleep Quality, and Quality of Life Among Older Adults
Aging is associated with progressive tissue deterioration resulting from a continuous decline in the ability to renew homeostatic cell regeneration and replace cells lost during tissue damage.
- Conditions
- Individuals Aged 60 and Over, Individuals Who Are Physically and Mentally Suitable to Practice Pranayama Breathing Technique, Individuals Without a Malignant Respiratory System Disease (Such as Bronchial and Lung Cancer), Individuals Without a Pathological Condition Affecting Their Level of Consciousness and Concentration
- Trial name
- NCT07451756
- Testing
- Pranayama group
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Malignant Glioma, Anxiety
Psychological Intervention For Brain Tumor Caregivers
This study is testing a supportive psychosocial intervention for caregivers of people who have malignant brain tumors such as gliomas or other high-grade primary brain tumors.
- Conditions
- Malignant Glioma, Anxiety, Caregiver Burden, Malignant Brain Tumor
- Trial name
- NCT04109209
- Testing
- Psychosocial Intervention Group, Usual Care Group
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
GBM, DIPG Brain Tumor
Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma
Primary brain malignant tumor has become the first lethal tumor in children and young adults, and the treatment is limited, and the prognosis of patients is poor.
- Conditions
- GBM, DIPG Brain Tumor, Medulloblastoma
- Trial name
- CSAγδTBMG (NCT06396481)
- Testing
- Vγ9Vδ2 T cell
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Malignant Brain Neoplasm
Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI
This trial looks to study the safety and feasibility of using oxygen-enhanced molecular MRI to understand how cancer cells use oxygen differently than normal cells.
- Trial name
- NCT04460495
- Testing
- Arterial Spin Labeling Magnetic Resonance Imaging, pH-Weighted amine CEST, Oxygen-weighted SAGE-EPI
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Glioblastoma, Gliosarcoma
Phase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG)
Primary objective: To evaluate activity of imatinib mesylate and hydroxyurea among patients with progressive/recurrent grade II low-grade glioma (LGG) as measured by 12-month progression free survival Secondary objectives: To…
- Trial name
- NCT00615927
- Testing
- Imatinib Mesylate & Hydroxyurea
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Duke University
Chronic Respiratory Diseases, Cardiovascular and Cerebrovascular Diseases
Chinese Population Health and Multimorbidity Study
The Chinese Population Health and Multimorbidity Study (CPHMS; initially named China Pulmonary Health Study, CPHS) was a large-scale epidemiological survey designed to investigate the pulmonary health of Chinese adults aged 20…
- Conditions
- Chronic Respiratory Diseases, Cardiovascular and Cerebrovascular Diseases, Malignant Tumors, Endocrine and Metabolic Diseases
- Trial name
- CPHMS (NCT07026370)
- Where
- China
- Volunteers
- 50,991 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Recurrent Atypical/malignant Meningioma
Apatinib in the Treatment of Recurrent Atypical/malignant Meningioma in Adults
Apatinib mesylate may be an effective treatment for recurrent atypical/malignant meningioma. This prospective clinical study is now planned to verify the effectiveness and safety of apatinib mesylate in the treatment of relapsed…
- Trial name
- NCT04501705
- Testing
- Apatinib Mesylate
- Where
- China
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Sanbo Brain Hospital
Spinal Metastases, Spinal Tumor
En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.
The purpose of this clinical trial is to explore the impact of En bloc surgery and separation surgery combined with radiation therapy on the prognosis and survival of patients with spinal oligometastatic cancer, describe the…
- Conditions
- Spinal Metastases, Spinal Tumor, Radiotherapy, Malignant Bone Tumor
- Trial name
- NCT06120426
- Testing
- total en bloc spondylectomy
- Where
- China
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Malignant Glioma
Prognostic Awareness and Patient-Physician Communication in Malignant Glioma
The purpose of this study is to learn more about the understanding patients with brain tumors have of their disease and their communication with their physician.
- Trial name
- NCT02023346
- Testing
- surveys and cognitive tests
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Carcinoma, Malignant Digestive System Neoplasm
Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital
This study examines how the American College of Surgeons Geriatric Surgery Verification Program, also called the ACS GSV Program, is implemented at the James Cancer Hospital.
- Conditions
- Breast Carcinoma, Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Genitourinary System Neoplasm
- Trial name
- NCT07606287
- Testing
- Serious Illness Conversation Program training, ACS Geriatric Surgery Verification Program Implementation
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Leukemia, Myeloid, Acute, Leukemia, B-cell
Precision Exercise in Children With Malignant Hemopathies
In the early years of life and during adolescence, physical activity is crucial for good development of motor skills. It is even more so for those children and young people who are forced to undergo anti-cancer therapies and…
- Conditions
- Leukemia, Myeloid, Acute, Leukemia, B-cell, Leukemia, T Cell, Lymphoma, Hodgkin
- Trial name
- SportTherapy (NCT04090268)
- Testing
- Sport Therapy
- Where
- Italy
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Stage IV Lung Cancer, Malignant Brain Tumor
A Computer-Based Intervention for Distance Caregivers of Parents With Advanced Cancer
This pilot clinical trial studies the feasibility and effectiveness of a new computer-based communication intervention in supporting distance caregivers of patients with advanced lung or brain cancer.
- Trial name
- NCT02128373
- Testing
- Usual care, computer-assisted intervention, Distress Thermometer
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Malignant Brain Neoplasm, Malignant Solid Neoplasm
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers).
- Conditions
- Malignant Brain Neoplasm, Malignant Solid Neoplasm, Multiple Sclerosis, Neuroendocrine Tumor
- Trial name
- NCT06788886
- Testing
- Biospecimen Collection, Exercise Intervention, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Brain Neoplasm, Primary, Brain Neoplasms, Malignant
Risk Factors for Adult-Onset Brain Tumors
Study Objective: Brain tumors are poorly understood. The purpose of this research is to examine whether factors in lifestyle play a role in brain tumor development.
- Conditions
- Brain Neoplasm, Primary, Brain Neoplasms, Malignant, Brain Neoplasms, Benign
- Trial name
- NCT00592865
- Where
- 5 sites in United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Postoperative Pain, Acute, Postoperative Depression
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
The purpose of this research study is to learn how two different supportive programs may help women feel better after surgery. This study will measure if one type of supportive program is more useful than the other for improving…
- Conditions
- Postoperative Pain, Acute, Postoperative Depression, Anxiety, Sleep Disturbance
- Trial name
- NCT05625360
- Testing
- eHealth Mindful Movement and Breathing, Life Impacts Reflection, PROMIS Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences