Clinical trials: Machine Learning
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Artificial Intelligence-assisted Evaluation of Pulmonary HYpertension
Pulmonary hypertension represents a challenging and heterogeneous condition that is associated with high mortality and morbidity if left untreated.
- Trial name
- AIPHY (NCT05566002)
- Testing
- Right heart catheterization
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Dental Caries
AI-Based Detection of Dental Caries in Children
This study aims to evaluate the effects of an artificial intelligence (AI)-based caries detection system on the diagnosis and categorization of dental caries in pediatric patients.
- Trial name
- NCT06984029
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Noura Nageh Ramadan Ahmed
Esophageal Cancer, Head and Neck Cancer
Early Detection of Esophageal Squamous Cancer With the Capsule Sponge Device
Esophageal squamous cell carcinoma accounts for ~90% of the nearly half-million annual incident cases of esophageal cancer worldwide.
- Conditions
- Esophageal Cancer, Head and Neck Cancer, Squamous Cell Carcinoma
- Trial name
- ANGELA (NCT06418516)
- Testing
- Capsule-sponge
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Injury Traumatic, Injuries
Trauma Follow-Up Prediction (Project 2: Aim 2)
Approximately 9% of the world's deaths, more than 5 million deaths annually, are due to injury. In high-income countries, where the epidemiology and outcomes of traumatic injury are well characterized, trauma primarily affects…
- Trial name
- NCT05464017
- Testing
- Optimized version of the mHealth screening tool (intervention) using the machine learning approach
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- University of Buea
Movement Disorders, Parkinson Disease
Handwriting Analysis in Movement Disorders
Handwriting is a complex cognitive prowess that deteriorates in patients affected by neurodegenerative diseases, including movement disorders.
- Conditions
- Movement Disorders, Parkinson Disease, Writing Disorder
- Trial name
- HANDWRML (NCT05355480)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Asthma COPD
Oscillometry and Machine Learning Approaches
Unicentric retrospective study designed to analyses the performance of various machine learning approaches to predict patterns of chronic respiratory diseases such as asthma, based mainly on clinical information and respiratory…
- Trial name
- NCT07447596
- Testing
- 1
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Attention Deficit Hyperactivity Disorder
Αn Information System for Symptom Diagnosis and Improvement of Attention Deficit Hyperactivity Disorder (ADHD360)
ADHD360 will be an innovative integrated platform for early ADHD diagnosis and intervention against its symptoms. In the core of the platform design there will be a serious game along with a mobile application to monitor behavior…
- Trial name
- ADHD360 (NCT04362982)
- Testing
- ADHD360 platform: An intervention intergrating a serious game along with a mobile application for daily behavioral monitoring.
- Where
- Greece
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
COVID-19
International Validation of Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms
1. Deploy wearable COVID sensor to collect high resolution physiological data (temperature, cardiac, respiratory and physical activity) from COVID positive patients. 2.
- Trial name
- NCT05334680
- Testing
- ANNE Sensor
- Where
- 3 sites in India
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Arun Jayaraman, PT, PhD
Bipolar Disorder Depression, Major Depression
AI-based Multi-center Research on Identification/Classification/Aided Diagnosis of Mood Disorder
At present, diagnosis and recognition of depression and bipolar disorder are mainly based on subjective evidence such as clinical interview and scale evaluation.
- Trial name
- NCT05608135
- Where
- China
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Diabetes
Clinical Diagnosis of Diabetes Using Surface-enhanced Raman Spectroscopy Liquid Biopsy and Machine Learning
This project aims to adapt the gold nanoparticle-based surface-enhanced Raman spectroscopy (SERS) technology to clinical application.
- Trial name
- NCT06862778
- Testing
- SERS
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
Infections
Validation of Betalactam ML Prediction Models - TDMAide
The goal of this study is to learn about the real wold behavior of developed machine learning models that predict the plasma concentration of piperacillin-tazobactam and meropenem in critically ill patients admitted to the…
- Trial name
- TDMAide (NCT06026852)
- Testing
- Prediction of plasma concentration of piperacillin-tazobactam or meropenem, Determination of plasma concentration of piperacillin-tazobactam or meropenem, Daily short questionnaire
- Where
- Belgium
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Ovarian Cyst
Assessment of Ovarian Cysts Using Machine Learning
The study aims at creating a prediction model using machine learning algorithms that is capable of predicting malignant potential of ovarian cysts/masses based on patient characteristics, sonographic findings, and biochemical…
- Trial name
- OCID (NCT05342298)
- Testing
- prediction model
- Where
- 2 sites in Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Assiut University
Glioma
Histopathology Images Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence
This registry aims to collect clinical, molecular and radiologic data including detailed clinical parameters, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and images of HE slices in…
- Trial name
- NCT04217044
- Testing
- Histopathology images based prediction of molecular pathology
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Women's Health, Annual Visit
Precision Nudging Drives Wellness Visit Attendance at Scale
The purpose of the present randomized controlled trial is to explore the effectiveness of a 12-month well woman digital health intervention leveraging Precision Nudging - the application of behavioral science and reinforcement…
- Conditions
- Women's Health, Annual Visit, Well Visit, Health Behavior
- Trial name
- NCT05509049
- Testing
- Precision nudging, Standard of care
- Where
- United States
- Volunteers
- 30,068 people, healthy volunteers welcome
- Sponsor
- Lirio
Colorectal Cancer (Diagnosis), Non-cancer Controls
Epigenetic Signature for CRC Early Detection
The epiCED is a noninvasive blood-based assay designed for early detection of colorectal cancer (CRC) using circulating cell-free DNA (cfDNA) 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) epigenetic markers.
- Conditions
- Colorectal Cancer (Diagnosis), Non-cancer Controls, DNA Methylation, Cell Free DNA
- Trial name
- epiCED (NCT07224854)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Gingivitis
AI Gum Health Evaluation with Smartphone
Background The most common dental diseases are tooth decay (caries) and gum disease (gingivitis and periodontitis). Obviously, these diseases are caused by dental plaque (bacterial biofilm).
- Trial name
- NCT05685355
- Testing
- Standardized intraoral photography
- Where
- Hong Kong
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment, Alzheimer Disease
Alzheimer's and Blood Glucose Levels
The Alzheimer's and Blood Glucose Levels Study is researching the differences in blood glucose levels between people with and without Mild Cognitive Impairment or Alzheimer's disease with the aim of early detection of Alzheimer's…
- Trial name
- NCT04614376
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bio Conscious Technologies Inc.
Diabetes Mellitus, Type 2, Liver Diseases
Validate Smart Breath Analyzer as Screening Tool for Diabetic, Hepatic, Renal, Lung, and Other Metabolic Disorders
This is a prospective, multicentric, non-treatment study to build and validate a portable, non-invasive smart breath analyzer that can screen underlying health issues using exhaled breath.
- Conditions
- Diabetes Mellitus, Type 2, Liver Diseases, Kidney Diseases, Lung Diseases
- Trial name
- RESPYR-SBA (NCT07646015)
- Where
- India
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Respyr
Exercise Training, Exercise Behavior
Adaptive Self-Efficacy-Based AI Coaching for Cycling
The primary objective of this study is to evaluate whether adaptive, AI-delivered personalized self-efficacy-based AI coaching based on real-time physiological and performance feedback enhance indoor cycling power output during a…
- Conditions
- Exercise Training, Exercise Behavior, Exercise Adherence Challenges, Motivation for Physical Activity
- Trial name
- AI (NCT07318233)
- Testing
- Group 1: Self-efficacy-based AI coaching, Group 2: Static AI Affirmations
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Acute Pain, Emergencies
Machine Learning for Risk Stratification in the Emergency Department (MARS-ED)
Rationale Identifying emergency department (ED) patients at high and low risk shortly after admission could help decision-making regarding patient care.
- Trial name
- MARS-ED (NCT05497830)
- Testing
- RISK-INDEX
- Where
- Netherlands
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center