Clinical trials: MRI Sedation
MRI Sedation
Safety and Efficacy of Dexmedetomidine (DEX) for Sedation of Subjects ≥1 Month to <17 Years Undergoing MRI Scans
This is a randomized, double-blind, dose-ranging study of the efficacy and safety of dexmedetomidine (DEX) when used with propofol as needed, for procedural sedation of pediatric subjects ≥1 month to <17 years of age undergoing…
- Trial name
- NCT04237792
- Testing
- dexmedetomidine, propofol
- Where
- 23 sites in United States, Japan
- Volunteers
- 128 people
- Sponsor
- Pfizer
Anesthesia, Pain
Memory & Conditioning Under Anesthesia
The purpose of this study is to determine the effects of pain on long-term memory and conditioned physiologic responses in the presence and absence of distinct intravenous anesthetics.
- Trial name
- MCA (NCT04062123)
- Testing
- Dexmedetomidine, Propofol, Fentanyl
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Keith M Vogt
Sedation
Comparison of Outcomes During MRI Sedation With Midazolam-dexmedetomidine Versus Ketamine-dexmedetomidine
This study will compare 2 different sedation drugs (Ketamine and Midazolam) when they are used with another sedating medicine called Dexmedetomidine for MRI sedation.
- Trial name
- NCT02129426
- Testing
- Ketamine, Midazolam, Dexmedetomidine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Louisville
Airway Remodeling
Airway Dimension Study in Children Undergoing MRI Sedated With Propofol and Dexmedetomidine
Sedation is required in infants and children to successfully complete MRI while maintaining respiratory and hemodynamic stability. Limited access to the patient may pose a safety risk during MRI examination.
- Trial name
- NCT01505933
- Testing
- Dexmedetomidine, propofol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Milton S. Hershey Medical Center
Safety and Efficacy of Sedation Medications
Comparing Safety and Efficacy of Dexmedetomidine and Propofol
This is a prospective, open label randomized study. The purpose of this study is to compare propofol with dexmedetomidine for pediatric monitored anesthesia care for MRI, specifically identifying important patient demographics…
- Trial name
- NCT01152021
- Testing
- Dexmedetomidine, Propofol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Dexmedetomidine Induced Sedation
Combined Electroencephalogram, Magnetic Resonance Imaging-Positron Emission Tomography of Dexmedetomidine Induced Sleep
The investigators are doing this research study to find out how and where dexmedetomidine, a sedative anesthetic, acts in the brain.
- Trial name
- NCT01485380
- Testing
- dexmedetomidine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Headache, Tumor
Dexmedetomidine and Propofol for Pediatric MRI Sedation
The purpose of this study is to compare the results of combining two anesthetic medications (dexmedetomidine and propofol) in low doses with a standard dose of a single drug that is commonly used to provide sedation/anesthesia…
- Conditions
- Headache, Tumor, Seizure Disorder, Neurofibromatoses
- Trial name
- NCT03513757
- Testing
- propofol, Dexmedetomidine, Glycopyrrolate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Epilepsy, Cerebral Palsy
A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging
This is a pilot study to determine if a standard bolus dose and infusion of dexmedetomidine can significantly decrease the dose of propofol (infusion) required for accomplishing an MRI.
- Conditions
- Epilepsy, Cerebral Palsy, Developmental Delay
- Trial name
- NCT02633241
- Testing
- Dexmedetomidine bolus and high infusion-Propofol, Dexmedetomidine bolus and low infusion-Propofol, Dexmedetomidine bolus only - Propofol
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Joseph Cravero