Clinical trials: MRI Imaging
Gout
An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels.
The purpose of this study is to show that patients with gout suffer from chronic inflammation of their joints, observable by MRI, even in the absence of symptomatic gouty attacks.
- Trial name
- NCT01112982
- Testing
- Magnetic Resonance Imaging, Febuxostat, Colchicine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of South Florida
Virtual Reality, Paediatrics
Virtual Reality Preparation for Medical Imaging
This pilot project aims to establish evidence to investigate whether a virtual reality intervention can be implemented to reduce anxiety and efficiently prepare children for non-sedated MRI assessments.
- Conditions
- Virtual Reality, Paediatrics, Radiology
- Trial name
- VR-MRI (NCT03931382)
- Testing
- Virtual Reality Simulator, Mock MRI Simulator, Standard Preparation Manual
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Cystic Fibrosis
Study of the Effect of VX-770 on Hyperpolarized Helium-3 Magnetic Resonance Imaging in Subjects With Cystic Fibrosis and the G551D Mutation
Cystic Fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The encoded protein, CFTR, is an epithelial chloride ion channel responsible for aiding in the regulation of salt…
- Trial name
- NCT01161537
- Testing
- VX-770
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Poor Peripheral Perfusion
Magnetic Resonance Imaging (MRI) to Assess Radial Artery Compression and Arterial Perfusion While TR Band is Applied
Subjects' radial artery diameters and plethysmography waveforms will be recorded by MRI and pulse oxymetry at varying levels of radial artery compression by the Terumo TR Band.
- Trial name
- NCT02478671
- Testing
- TR Band
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Terumo Medical Corporation
Cough
Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients
Persistent cough is a distressing symptom for people with respiratory disorders. Patients also often experience an ongoing urge-to-cough that prompts coughing, and which fails to resolve the sensation.
- Trial name
- NCT03722849
- Testing
- Adenosine Triphosphate, Capsaicin, Functional Brain Imaging
- Where
- Australia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Stuart Mazzone
Apnea of Prematurity, Intraventricular Hemorrhage
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Over the last 30 years the survival rates for babies born prematurely have improved greatly with research. As these babies grow up, we have found that many of the premature babies have learning and movement problems.
- Conditions
- Apnea of Prematurity, Intraventricular Hemorrhage, Brain Injury
- Trial name
- NCT00809055
- Testing
- Caffeine citrate
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Washington University School of Medicine
Congenital Heart Disease, Hypoplastic Left Heart Syndrome
Erythropoetin Neuroprotection for Neonatal Cardiac Surgery
Brain problems occur in neonatal open heart surgery with a frequency of 20-70%, seen on neurological examination, brain imaging such as magnetic resonance imaging (MRI), or long term development problems such as learning…
- Conditions
- Congenital Heart Disease, Hypoplastic Left Heart Syndrome, Transposition of the Great Arteries, Aortic Arch Hypoplasia or Interruption
- Trial name
- NCT00513240
- Testing
- Erythropoetin, Normal saline
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Baylor College of Medicine
Myocardial Perfusion Imaging, Magnetic Resonance Imaging
Myocardial Perfusion MRI
The object of this study is to compare four different dosages of Gadavist 1.0 in cardiac Magnetic Resonance Tomography (MRT) imaging with the imaging results of a cardiac SPECT examination in terms of diagnostic quality.
- Trial name
- NCT01490294
- Testing
- Gadobutrol (Gadavist,Gadovist, BAY86-4875)
- Where
- 14 sites in Austria, Germany and 2 more
- Volunteers
- 232 people
- Sponsor
- Bayer
ST-segment Elevation Myocardial Infarction
Distal Protection Device in ST-elevation Myocardial Infarction (STEMI)
The investigators examined the mechanism underlying the lack of benefit from distal protection and thrombus aspiration (DP-TA) in 126 patients with ST-elevation Myocardial Infarction (STEMI) in a prospective, randomized trial.
- Trial name
- NCT01384019
- Testing
- distal protection and thrombus aspiration (The GuardWire Plus (Medtronic Inc.)), c-PCI
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Bundang Hospital
Schizophrenia
Best Event Schizophrenia Trial--A Randomized Double-Blind Trial of Aripiprazole and Risperidone in Schizophrenia
This study is being conducted to find a way to predict how individual schizophrenic patients will respond if they are treated with different types of antipsychotic drugs.
- Trial name
- BEST (NCT00712270)
- Testing
- Aripiprazole, Risperidone
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Kettering Health Network
Persistent Atrial Fibrillation
The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with increasing morbidity and mortality. A catheter-based AF ablation technique that isolates pulmonary veins (PV) from the left atrium has been established…
- Trial name
- SIMPle-AF (NCT02918396)
- Testing
- Scar-Based Radio-frequency Ablation, Rotor Anchors Radio-frequency Ablation, Conventional PVI by Radio-frequency Ablation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Alzheimer Disease
Transmagnetic Stimulation Pilot in Early Stage Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative condition affecting 6.2 million individuals in the United States, resulting in an annual cost of care of $305 billion.
- Trial name
- NCT05292222
- Testing
- Intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HealthPartners Institute
Morbid Obesity, Liver Fat
Low-calorie Diet and Body Composition Prior to Roux-en-Y Gastric Bypass
Losing weight before undergoing Roux-en-Y gastric bypass (RYGB) surgery may reduce liver fat content and size thereby improving surgical outcomes.
- Trial name
- LCD (NCT02144597)
- Testing
- Liquid formula low-calorie diet (LCD), Roux-en-Y gastric bypass (RYGB), Control diet
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Ovarian Cancer
Evaluation of Response to the Neoadjuvant Chemotherapy for Advanced Ovarian Cancer by Multimodal Functional Imaging
This study evaluates the therapeutic response by modern FMRI and PET techniques with the perspective to exploit multimodal data (fusion MRI/PET).
- Trial name
- IMOVA (NCT02792959)
- Testing
- Functional Imaging previous the second course, Functional Imaging previous the surgery
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Institut Bergonié
Essential Tremor, Tremor
Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response
Essential Tremor (ET) is the most common tremor disorder, currently affecting an estimated 2.9 million Americans and leading to disability and decreased quality of life in 75% of cases.
- Trial name
- NCT02495883
- Testing
- Ethanol, Propranolol
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Local Anesthetic Complication, Local Anesthetic Drug Adverse Reaction
Defining Normal Postoperative Magnetic Resonance Imaging After Total Knee Arthroplasty
The aim of this study was to describe the postoperative "baseline" magnetic resonance imaging (MRI) appearance of the ipsilateral thigh musculature after total knee arthroplasty (TKA).
- Trial name
- NCT04821245
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Benaroya Research Institute
Parkinson Disease, Physical Activity
Neuroplasticity in Parkinson´s Disease After Training
This project aims to determine the effects of the HiBalance program on neuroplastic changes in people with mild to moderate Parkinson´s disease.
- Conditions
- Parkinson Disease, Physical Activity, Gait Disorders, Neurologic, Neural Degeneration
- Trial name
- BETA-PD (NCT03213873)
- Testing
- HiBalance, Speech and communication therapy
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Karolinska Institutet
Asthma
Evaluation of Triple Therapy Using Magnetic Resonance Imaging in Asthma
The purpose of this study is to evaluate the effectiveness of treatment with triple therapy an inhaler that contains three types of asthma medications, on participants with poorly controlled asthma.
- Trial name
- ETHA (NCT04651777)
- Testing
- FF/UMEC/VI
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Dr. Grace Parraga
Central Nervous System Diseases
Safety and Efficacy of Gadobutrol 1.0 Molar ( Gadavist ) in Patients for Central Nervous System (CNS) Imaging
This is a study involving the use of Magnetic Resonance Imaging (MRI) contrast agents called Gadavist. The purpose of this study is to look at the safety (what are the side effects) and efficacy (how well does it work) of…
- Trial name
- NCT00623467
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875)
- Where
- 37 sites in United States, Argentina and 3 more
- Volunteers
- 343 people
- Sponsor
- Bayer
Chronic Traumatic Encephalopathy
Tau Imaging of Chronic Traumatic Encephalopathy
Chronic traumatic encephalopathy (CTE) is a progressive degenerative brain disease with symptoms that include memory loss, problems with impulse control, and depression that can lead to suicide.
- Trial name
- NCT02191267
- Testing
- [F18]-T807, [F18]-Florbetapir, MRI/MRS
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital