Clinical trials: MANDIBLE
Complete Edentulism
Prosthetic Complications in Fixed All-On-Four Prosthesis Reinforced with Poly Ether Ether Ketone (PEEK) Versus Cobalt Chromium (Co-Cr) Framework
Prosthetic complication will be measured for all-on-four fixed prosthesis in the mandibular arch in completely edentulous patients.
- Trial name
- NCT06631573
- Testing
- fixed all-on-four prosthesis reinforced with PEEK framework., Fixed all-on-four prosthesis reinforced with Co-Cr framework
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Cairo University
Obstructive Sleep Apnea
Efficacy of the OrthoApnea NOA® Mandibular Advancement Device in the Management of Obstructive Sleep Apnea.
The objective of this study is to assess the efficacy of the Orthoapnea NOA® mandibular advancement device and describe the percentage of advancement (%) needed to reach efficacy, and to retrospectively compare with other MAD…
- Trial name
- NCT05139303
- Testing
- Orthoapnea NOA®
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Isabel Moreno Hay
Temporomandibular Disorder
Efficacy of Therapeutic Exercise and Pain Neurophysiology Education in Temporomandibular Disorders
The aim of this study is to compare the effects in pain of two different treatments in pacients with temporomandibular disorders (TMD).
- Trial name
- NCT06502769
- Testing
- Therapeutic Exercise, Pain Neurophysiology Education
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Alcala
Class II Furcation Defect
Treatment of Class II Mandibular Furcation Defects
The aim of this study is to investigate the clinical efficiency and radiographic outcomes following minimally invasive surgical technique with xenograft and i-PRF versus i-PRF in the management of class II furcation defects in…
- Trial name
- NCT07876973
- Testing
- Injectable-PRF (I-PRF), sticky bone (I-PRF+Xenograft)
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Temporomandibular Joint Disorders
Patient Satisfaction in Occlusal Splints Fabricated Using Fully Digital Versus Conventional Workflow
According to published literatures, the prevalence of TMD is approximately 10% in patients over 18 years of age with a considerable proportion being women of reproductive age.
- Trial name
- NCT06985173
- Testing
- Occlusal splints manufactured with fully digital workflow., Occlusal splints manufactured with Conventional workflow
- Volunteers
- 32 people
- Sponsor
- Cairo University
Crowding of Anterior Mandibular Teeth
Evaluation of the Effectiveness of Piezocision and Micro-osteoperforation in Alleviating Mandibular Anterior Crowding
In recent times, many patients want their treatment duration to be reduced, because lengthy orthodontic treatment duration is associated with negative sequelae such as discomfort, pain, white spot lesions, and decreased patient's…
- Trial name
- NCT04940351
- Testing
- GROUP - A: PIEZOCISION GROUP, GROUP- B: MICRO-OSTEOPERFORATION GROUP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Bone Loss
CAD-CAM PEEK Framework for All-on-4 Implants
This study was conducted to evaluate the clinical peri-implant soft tissue changes during the first year after occlusal loading and the ridge base relation after 3 years for mandibular computer-aided design and computer-aided…
- Trial name
- NCT06017596
- Testing
- PEEK framework
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tumor, Facial Fracture
A Post Market Clinical Follow-up Study on Biomet Microfixation HTR PEKK (Midface), Facial & Mandibular Plates.
This study will address medical devices manufactured by Biomet Microfixation (d.b.a. Zimmer Biomet) designed for fixation and stabilization of the facial and mandibular skeleton.
- Conditions
- Tumor, Facial Fracture, Mandibular Fractures, Fibrous Dysplasia
- Trial name
- NCT04931056
- Testing
- Titanium Facial Plates, Titanium Mandibular Plates, Add-on Condyle
- Where
- Argentina
- Volunteers
- 91 people
- Sponsor
- Zimmer Biomet
Obstructive Sleep Apnea Syndrome
Clinical Impact of 2 Types of Mandibular Retention Devices - Narval O.R.M CadCam Design vs Narval O.R.M Traditional Design - on Obstructive Sleep Apnea (OSA) Therapy: ESTAMPS Study
ESTAMPS is a randomized clinical trial with a crossover design: Main objective is to compare impact of 2 different Mandibular Retention Device (MRD) designs (Narval MRD CadCam (CC) design vs Narval MRD traditional (trad) design)…
- Trial name
- ESTAMPS (NCT02755662)
- Testing
- Mandibular Retention Device
- Where
- France
- Volunteers
- 12 people
- Sponsor
- ResMed
Temporomandibular Joint Dysfunction
Electromyographic Evaluation of the Efficacy of Manual Therapy in Temporomandibular Joint Dysfunction.
Individuals with temporomandibular joint dysfunction (TMD) may experience changes in muscle activation as a result of symptoms such as pain and limitation of movement.
- Trial name
- NCT05420896
- Testing
- Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bahçeşehir University
Temporomandibular Disorders (TMD)
INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR
Temporomandibular disorders (TMD) encompass all temporomandibular muscular and osteoarticular conditions. TMD affects 31% of the adult population, with chronic, debilitating pain in 10% of cases.
- Trial name
- DiagDTM (NCT07499869)
- Testing
- digital jaw impressions and Modjaw® records
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Periodontitis
Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis
Statins are one of the lipid lowering drugs that help in reducing cholesterol levels in the body by specifically inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase; which is a rate limiting enzyme for cholesterol…
- Trial name
- NCT02800902
- Testing
- Rosuvastatin, Atorvastatin
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Pelvic Floor Disorders, Temporomandibular Joint Disorders
The Relationship Between the Parameters Affecting the Functionality of the Pelvic Floor and the Temporomandibular Joint
The aim of our study is to examine the relationship between the parameters affecting the pelvic floor and temporomandibular joint (TMJ) functionality and to emphasize the necessity of investigating combined and coordinated…
- Trial name
- NCT05957601
- Testing
- No intervention was made as it was a descriptive epidemiological study.
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Mandibular Class Iv Fractures
Patient-Specific Guides vs. Classical Workflow in Class IV Mandibular Fracture Fixation
This study aims to overcome the limitations of current, standard approach of mandibular fracture reduction and fixation including improper alignment of segments, malocclusion, nerve affections and related teeth roots injury.
- Trial name
- NCT07153354
- Testing
- patient-specific screw holes locating surgical guide and pre-bent plates, 2 titanium per-bent mini plates
- Volunteers
- 20 people
- Sponsor
- Mohamed abdelsalam Gaber elkhouly
Retrognathism, Prognathism
Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy
The bilateral sagittal split osteotomy (BSSO) of the mandible is one of the most used surgical techniques to achieve a harmonious jaw relation in the context of orthognathic surgery.
- Conditions
- Retrognathism, Prognathism, Orthognathic Surgery, Neurosensory Disorder
- Trial name
- NCT05536596
- Testing
- Orthognathic Surgery, Melatonin 10 MG Oral Tablet, Hydroxycobalamin
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Impacted Third Molar Tooth
Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar
Background: One of the most frequent surgical operations in dentistry is the surgical extraction of the impacted mandibular third molar, which is accompanied by a sequelae of swelling, trismus, and pain.
- Trial name
- NCT06144983
- Testing
- Alvogyl, Chlorhexidine Gluconate
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Partially Edentulous Jaw
Validation of the Jawbone Anatomy Classification in Endosseous Dental Implant Treatment
The purpose of this study is to evaluate validation and clinical assessment of the earlier proposed clinical and radiological classification of the jawbone anatomy in endosseous dental implant treatment. Expected results.
- Trial name
- NCT02054676
- Testing
- Cone-Beam Computed Tomography preoperative evaluation., Intraoperative edentulous jaw segment parameters evaluation., Endosseous dental implant placement.
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Pain
Postoperative Pain After Activation of Irrigant
The purpose of this research is to analyze the levels of pain after cleaning and shaping in individuals who are receiving root canal therapy using the IVAC irrigation approach, and those who are treated with ultrasonic irrigation…
- Trial name
- NCT06528574
- Testing
- Conventional root canal treatment, Ultrasonic, Apical negative pressure
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Symptomatic Irreversible Pulpitis
Anaesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine With Symptomatic Irreversible Pulpitis
The aim of this randomized, double-blinded, clinical trial was to assess the effect of 3.6 mL 2% mepivacaine hydrochloride with 1:100,000 epinephrine compared to 3.4 mL 4% articaine hydrochloride with 1:100,000 epinephrine on the…
- Trial name
- NCT04822415
- Testing
- Mepivacaine, Articaine
- Volunteers
- 330 people
- Sponsor
- Cairo University
Socket Perservation
Socket Preservation Using Biodentin Versus Xeno Graft for Single Rooted Teeth
socket preservation using biodentin versus xeno graft for single rooted mandibular teeth
- Trial name
- NCT06695208
- Testing
- Biodentine
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University