Clinical trials: Lymphedema Primary, open to volunteers
Lymphedema
Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose…
- Trial name
- LYMPHODYS (NCT05629026)
- Testing
- Micro-biopsies
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Vascular Anomaly, Osler Rendu Disease
Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study
There are no prospective studies of pregnancies for the diseases studied here in (Heredity Hemorrhagic Telangiectasia, Marfan syndrome or related, primary lower limb lymphedema, superficial arteriovenous malformations, and…
- Conditions
- Vascular Anomaly, Osler Rendu Disease, Marfan Syndrome or Related, Lymphedema Primary
- Trial name
- COGRare5 (NCT04194619)
- Testing
- Questionnaire
- Where
- 37 sites in France
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Lymphedema Primary
Inelastic Compression Use in Primary Lymphedema
Primary lymphedema in children is a rare, chronic condition caused by congenital or inherited developmental abnormalities in the lymphatic system that lead to persistent fluid buildup and swelling.
- Trial name
- Primary LE (NCT07866599)
- Testing
- Compression device with medium pressure (23-32 mmHg)
- Volunteers
- 30 people
- Sponsor
- University School of Physical Education, Krakow, Poland
Primary Lymphedema, Secondary Lymphedema
Biological Profile of Primary and Secondary Lymphedema: Inflammatory, Endothelial, Metabolic, Lymphatic, and Fibrotic Markers
This observational, cross-sectional study aims to characterize the biological profile of primary and secondary lymphedema by investigating five interconnected biological domains: T helper 2 (Th2)-related inflammation, endothelial…
- Trial name
- LYMPH5 (NCT07770399)
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Breast Neoplasm Malignant Primary, Lymphedema Arm
Agentic AI App and Home Bioimpedance Monitoring for Endocrine Therapy Adherence and Lymphedema in Breast Cancer Survivors
As survival rates following breast cancer surgery continue to improve, long-term survivorship management has emerged as a crucial clinical priority.
- Conditions
- Breast Neoplasm Malignant Primary, Lymphedema Arm, Medication Adherence, Ductal Carcinoma In Situ
- Trial name
- Pinkmate (NCT07911839)
- Testing
- Cohort1: Pinkmate Agentic AI-ePRO Active Management Platform, Cohort1: Pinkmate Basic Medication Reminders and Standard Outpatient Care, Cohort2: InBody BWA ON Home Bioimpedance Monitoring and Behavioral App
- Where
- South Korea
- Volunteers
- 264 people
- Sponsor
- Chang-Ik Yoon
Lymphedema, Mastectomy
Primary Surgical Prevention of Breast Cancer-related Lymphedema
Lymphedema refers to edema caused by insufficient drainage of interstitial fluid through the lymphatic circulation system. It occurs mainly in the upper and lower extremities and causes chronic inflammation, and finally fibrous…
- Conditions
- Lymphedema, Mastectomy, Breast Cancer
- Trial name
- LYMPHA (NCT04687956)
- Testing
- LYMPHA, control
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Gangnam Severance Hospital