Clinical trials: Lymphedema, open to volunteers
Mastectomy; Lymphedema
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy
Breast cancer is the most common type of cancer in women. Removal of the breast, called "mastectomy", is performed either when there is cancer-or an increased risk of cancer-in the breast.
- Trial name
- NCT05444361
- Testing
- Cryoneurolysis
- Where
- 5 sites in United States
- Volunteers
- 216 people
- Sponsor
- University of California, San Diego
Breast Cancer Related Lymphedema
EFFECT OF ESWT ON BREAST-CANCER RELATED LYMPHEDEMA
The aim of this study is to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) combined with complete decongestive therapy (CDT) compared with CDT alone in patients with breast cancer-related lymphedema.
- Trial name
- NCT07854262
- Testing
- Complete Decongestive Therapy, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
Lymphedema of Face, Neoplasms
Manual Lymph Drainage for External Lymphedema
This study will evaluate the feasibility of a randomized controlled trial. The future randomized controlled trial will compare two groups following different intensities of manual lymphatic drainage for external head- and neck…
- Conditions
- Lymphedema of Face, Neoplasms, Radiotherapy Side Effect, Lymphedema Due to Radiation
- Trial name
- MLD-HN (NCT07215169)
- Testing
- HIT, LIT
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Lund University
Breast Cancer (Early Breast Cancer), Postoperative Shoulder Dysfunction
Prehabilitation in Breast Cancer Surgery
This prospective, randomized, assessor-blinded, parallel-group clinical trial evaluates the effectiveness of a home-based upper extremity-focused prehabilitation program in women undergoing breast cancer surgery.
- Conditions
- Breast Cancer (Early Breast Cancer), Postoperative Shoulder Dysfunction, Lymphedema Arm, Cancer Rehabilitation
- Trial name
- NCT07425379
- Testing
- Home-Based Prehabilitation Exercise Program, Usual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Lymphedema Lower Extremity
Assessment of the Efficacy of the Dynamic Decongestive System in the Maintenance Phase of Lower Limb Lymphedema
The trial aims to determine whether the dynamic compression device, used in combination with elastic compression garments, is non-inferior to currently available compression devices (CACD) during the maintenance phase of…
- Trial name
- EDYDES-maint (NCT07603531)
- Testing
- Control group: Currently available compression devices, DDS group: Dynamic compression device (DDS)
- Where
- 3 sites in France, Germany
- Volunteers
- 98 people
- Sponsor
- Jean-Paul Belgrado
Post Mastectomy Lymphedema
Effect of Thera-Band Versus Swiss Ball Exercises on Postural Stability in Post Mastectomy Lymphedema
The purpose of the study is to determine the effect of Thera-band exercises versus Swiss ball exercises on postural stability in unilateral post mastectomy lymphedema.
- Trial name
- NCT07019311
- Testing
- Thera-Band exercises, Swiss ball exercises, Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Lymphedema, Upper Extremity Lymphedema
Comparison of Reliability, Time Cost, and Participant Comfort of Lymphedema Assessments in Upper Extremity
This study aims to evaluate and compare the measurement reliability, total time cost (preparation, acquisition, post-processing), and participant comfort of conventional limb volume measurement methods (water displacement…
- Conditions
- Lymphedema, Upper Extremity Lymphedema, Breast Cancer Related Lymphedema, Edema
- Trial name
- NCT07921290
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Breast Cancer-Related Lymphedema, BCRL
Comparison of IPC Therapy as an Alternative or an Adjunct to MLD Within CDT for BCRL
Breast cancer is the most common cancer among women worldwide and lymphedema is one of its most significant complications. Breast cancer-related lymphedema (BCRL) may develop shortly after treatment or even years later, causing…
- Trial name
- NCT07154043
- Testing
- Complete Decongestive Therapy (CDT), CDT + Intermittent Pneumatic Compression (IPC), CDT without Manual Lymph Drainage plus Intermittent Pneumatic Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Pamukkale University
Skin and Connective Tissue Diseases, Neglected Tropical Diseases
Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers
Skin-related Neglected Tropical Diseases (Skin NTDs) affect about 1.8 billion people worldwide, particularly in poor and rural communities where healthcare access is limited.
- Conditions
- Skin and Connective Tissue Diseases, Neglected Tropical Diseases, Leprosy, Buruli Ulcer
- Trial name
- SkincAIr (NCT07506967)
- Testing
- A mobile app with AI functionality for diagnosing skin-related NTDs
- Where
- 5 sites in Democratic Republic of the Congo, Ethiopia and 3 more
- Volunteers
- 2,420 people
- Sponsor
- Kenya Medical Research Institute
Lymphedema of Upper Limb
Novel MRI Techniques on Evaluation of Lymphedema
In this project, the investigators aim to investigate the imaging approaches for breast cancer-related secondary lymphedema. The clinical study aims to optimize the conventional MRI methods for mapping lymphedema and assess the…
- Trial name
- NCT05804643
- Testing
- Diffusion magnetic resonance imaging
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lymphedema
Topical Tacrolimus for Breast Cancer-related Lymphedema
The goal of this clinical trial is to investigate the effect of tacrolimus ointment in women with stage I or II breast cancer-related lymphedema.
- Trial name
- NCT06306274
- Testing
- Tacrolimus
- Where
- 3 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Lymphedema
The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)
The aim of the study is to investigate the short-term (within 2 weeks) effects of resistance exercise with and without compression garments on lower limb lymphedema(LLL).
- Trial name
- LymphEx (NCT07558317)
- Testing
- Resistance exercise
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Carsten Bogh Juhl
Lymphedema
Testing for Increased Lipoproteins (a) [LP(a)] in Lymphedema Patients: Li-LY
Lymphedema is a chronic disease that causes lymph to accumulate in the interstitial tissue. The lymphatic network is involved in the metabolism of lipids and lipoproteins, and this accumulation leads to lipid deposits in the…
- Trial name
- LiLY (NCT05962827)
- Testing
- lipoprotein (a)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Lymphedema, Gait Dysfunction
Impact of Virtual Reality (VR) Based Exercises on Lower Limb Lymphedema Outcomes (LELO)
This randomized controlled study aims to investigate the effects of virtual reality (VR)-assisted gait training, in addition to Complex Decongestive Therapy (CDT), on gait parameters, physical function, quality of life, and edema…
- Conditions
- Lymphedema, Gait Dysfunction, Physical Rehabilitation, Chronic Edema
- Trial name
- VR-LELO (NCT07472543)
- Testing
- Complex Decongestive Therapy (CDT) plus virtual reality (VR)-assisted gait training group, Complex Decongestive Therapy alone group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Lymphedema, Lymphedema Arm
Comparison of the Effects of Kinesio Taping and Compression Bandaging on Edema, Range of Motion, Upper Extremity Function, and Grip Strength in Patients With Breast Cancer-Related Lymphedema
This randomized crossover clinical trial aims to compare the effects of Kinesio Taping and compression bandaging on upper extremity edema, shoulder range of motion, upper extremity function, pain, and grip strength in patients…
- Conditions
- Lymphedema, Lymphedema Arm, Mastectomy
- Trial name
- NCT07919093
- Testing
- lymphedema treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Halic University
Lymphedema, Premature Birth
Infant Massage for Lymphedema and Comfort in Preterm Newborns
This randomized controlled trial investigates the effectiveness of infant massage in reducing symptoms of immobilization-related lymphedema and improving comfort in preterm newborns hospitalized in the Neonatal Intensive Care…
- Conditions
- Lymphedema, Premature Birth, Edema, Immobilization
- Trial name
- NCT07418814
- Testing
- Infant Massage Group
- Volunteers
- 40 people
- Sponsor
- Erzurum Technical University
Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy
Extracorporeal Shock Wave Therapy in Lower Extremity Lymphedema
Lower extremity lymphedema is a chronic and progressive condition associated with significant functional impairment and reduced quality of life.
- Conditions
- Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy, Edema Leg, Sham-controlled
- Trial name
- NCT07626645
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Leprosy, Lymphatic Filariases
Integrating Mental Health Into Neglected Tropical Disease Care in Ghana
Background Neglected Tropical Diseases (NTDs) are a group of diseases that are more common among the poorest people in the poorest countries.
- Conditions
- Leprosy, Lymphatic Filariases, Buruli Ulcer, Onchocerciasis
- Trial name
- IMAGINE (NCT07248462)
- Testing
- WHO Essential Care package for mental health and NTDs
- Volunteers
- 200 people
- Sponsor
- Liverpool School of Tropical Medicine
Breast Cancer Lymphedema, Survivorship
Lymphatic Response to Resistance Exercise in Breast Cancer Survivors
The objective of this study is 1) to study the acute and chronic effect of resistance therapeutic physical exercise (RTPE) in the prevention of breast cancer-related lymphedema (BCRL) in breast cancer survivors at risk using…
- Conditions
- Breast Cancer Lymphedema, Survivorship, Lymphedema of Upper Limb
- Trial name
- LinfoGYM (NCT06113627)
- Testing
- Resistance Therapeutic Exercise
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- University of Malaga
Post Mastectomy Lymphedema
Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy
This study aims to determine the combined effect of resisted deep breathing and Myofascial release on pain, respiratory efficiency, chest mobility and lymph edema in Postmastectomy.
- Trial name
- NCT07576270
- Testing
- Resisted Deep Breathing, Myofascial release
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University