Clinical trials: Lung Volume
Haemofiltration, Lung Mechanics
Effect of High volumeHemodiafiltration on Lung Oxygenation
High volume hemodiafiltration (HVHDF) has been used in septic patients to get hemodynamic improvement and possibly survival benefit.
- Conditions
- Haemofiltration, Lung Mechanics, Septic Patients
- Trial name
- NCT03853005
- Testing
- HVHDF, controlled
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
COPD, Lung Diseases
Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea
The purpose of this study is to determine whether indacaterol maleate 300 micrograms (mcg) is effective in the acute treatment of COPD and in particular on reducing lung hyperinflation and dynamic volumes.
- Conditions
- COPD, Lung Diseases, Dyspnea, Hypoxemia
- Trial name
- NCT01377051
- Testing
- Indacaterol maleate
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Milan
Asthma
Bronchodilatation Effects of a Small Volume Spacer Used With a Metered-Dose Inhaler
The purpose of the present study is to determine whether use of a small volume spacer is associated with better bronchodilatation in an unselected population of patients with documented reversible airflow limitations.
- Trial name
- MDI (NCT00465413)
- Testing
- Small volume spacer and/or Rinsing the mouth with water
- Where
- 2 sites in Taiwan
- Volunteers
- 300 people
- Sponsor
- Mackay Memorial Hospital
One-lung Ventilation (OLV), Video-assisted Thoracis Surgery (VATS)
Comparison of Different Ventilation Modes in Video-Assisted Thoracoscopic Lung Resection
One-lung ventilation (OLV) is required for video-assisted thoracoscopic surgery (VATS) lung resection, but it exposes the dependent lung to atelectasis, high driving pressures, and oxidative stress, and is associated with…
- Trial name
- OLV-VENT (NCT07866170)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Mechanical Ventilation, Positive End-Expiratory Pressure
Influence of Inspiratory Pause on Ventilatory Efficiency in Robotic Surgery. A Prospective Paired Study.
The investigators aim to determine if the modification of the end inspiratory pause (EIP) during mechanical ventilation adds benefit when applied to patients undergoing robotic surgery and who are ventilated under an…
- Conditions
- Mechanical Ventilation, Positive End-Expiratory Pressure, Anesthesia
- Trial name
- NCT05514366
- Testing
- Modifying EIP under a tOLA before pneumoperitoneum, Modifying EIP under a tOLA with pneumoperitoneum, Atelectasis test
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Chronic Obstructive Pulmonary Disease
Chest Wall Muscle Stretching and Acute Effects in Chronic Obstructive Pulmonary Disease
The study hypothesis is chest wall muscle stretching increase distribution of volume variation of thoracoabdominal wall and reduce electromyographic activity of respiratory muscles in patients with Chronic Obstructive Pulmonary…
- Trial name
- NCT01826669
- Testing
- Stretching
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Universidade Federal de Pernambuco
Newborn Morbidity, Respiratory Failure
Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC
Intubated preterm infants between 800-1200 grams and under 32 weeks of gestational age will start with PRVC ventilation mode, basal blood gases and work of breathing will measured.
- Conditions
- Newborn Morbidity, Respiratory Failure, Bronchopulmonary Dysplasia, Mechanical Ventilation Complication
- Trial name
- NCT04191239
- Testing
- GE ventilator with two different modes
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Obstructive Pulmonary Disease, COPD
Effect of QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) on Cardiac Function in COPD Patients
This mechanistic study is a single-center, randomized, double-blind, placebo-controlled, cross-over study to evaluate the effect of dual bronchodilation with QVA149 on cardiac and lung function parameters in hyperinflated COPD…
- Trial name
- CLAIM (NCT02442206)
- Testing
- QVA149
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Novartis Pharmaceuticals
Lung Cancer (NSCLC)
Comparison of SPECT/CT Perfusion and Volumetric CT Volume
The main aim of this study is to show that single photon emission tomography/Computer tomography (SPECT/CT) is a reliable examination to predict postoperative pulmonary function after segmentectomy, by comparing this predicted…
- Trial name
- VOLSEP (NCT06600204)
- Testing
- lung scintigraphy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Ventilator Associated Pneumonia (VAP)
Heparin Binding Protein Versus Platelet Count and Mean Platelet Volume Kinetics in the Diagnosis and Prognosis of VAP
mechanically ventilated for 48 hours or more and subsequently develop ventilator-associated pneumonia (VAP). After obtaining approval from the local ethical committee at the Faculty of Medicine, El-Minia University, and informed…
- Trial name
- NCT06993623
- Testing
- heparin binding protien
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Esraa Hamdy Thabit Riad
Respiratory Distress Syndrome
Effect of Different Ventilatory Strategies on Cardiac Function in Patients With Acute Respiratory Failure
Mechanical ventilation with low tidal volume (about 6 ml.kg-1) reduces mortality in ALI/ARDS patients respect to high tidal volume ventilation (about 12 ml.kg-1).
- Trial name
- VITALI (NCT00713713)
- Testing
- Mechanical ventilation with low and high tidal volume
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Lung Neoplasms, Pulmonary Disease
Does PEP Compensate the Reduction of Tidal Volume During One Lung Ventilation?
During general anesthesia, airway closure and the formation of atelectasis impair oxygenation. During one-lung ventilation, large tidal volumes are used to resume atelectasis with a risk of regional over distension and…
- Trial name
- REVOLU (NCT00534690)
- Testing
- One-Lung ventilation, One-Llung ventilation
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Bordeaux
Healthy Young Adults
High vs Low Volume Intensity Training With IMT On Pulmonary Function And Breathing Efficiency On Recreational Swimmers.
This study aims to evaluate the impact of inspiratory muscle training (IMT) on respiratory function and swimming performance in competitive swimmers.
- Trial name
- NCT06604741
- Testing
- Assigned Interventions for LVIMT, Assigned interventions for HVIMT
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)
Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency
Patients with advanced heterogeneous emphysema due to alpha1 antitrypsin deficiency might benefit from endoscopic implantation of intrabronchial valves.
- Trial name
- NCT01357460
- Testing
- Implantation of intrabronchial valves (IBV) (Spiration IBV)
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Heidelberg University