Clinical trials: Lung Transplantation, open to volunteers
Hematopoietic Stem Cell Transplantation (HSCT), Pulmonary Rehabilitation
Effects of Different Inspiratory Muscle Training Protocols in Hematopoietic Stem Cell Transplant Recipients
Introduction: After haematopoietic stem cell transplantation (HSCT), patients often experience complications such as respiratory difficulties, fatigue and decreased quality of life.
- Conditions
- Hematopoietic Stem Cell Transplantation (HSCT), Pulmonary Rehabilitation, Inspiratory Muscle Training
- Trial name
- NCT07061444
- Testing
- Inspiratory Muscle Training, Functional Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ceren Derya Gültekin
Work of Breathing, Lung Transplantation
Electrical Activity of the Diaphragm and Respiratory Mechanics During NAVA
Protective ventilatory strategy should be applied to reduce ventilator-induced lung injury (VILI) after Lung Transplantation (LTx) or in case of acute respiratory failure requiring invasive mechanical ventilation.
- Conditions
- Work of Breathing, Lung Transplantation, Neurally Adjusted Ventilatory Assist, Ventilator-Induced Lung Injury
- Trial name
- NAVAMECH (NCT05689476)
- Testing
- NAVA GROUP
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova
Lung Trasplant, Lung Transplantation
Study of Tacrolimus Melt-Dose® for Lung Transplant Patients
To evaluate, under usual clinical practice conditions and with a 12-month follow-up , the most relevant pharmacokinetic parameters of tacrolimus metabolism and safety, in patients with recent lung transplant (unilateral or…
- Trial name
- ESENCIAL (NCT07042035)
- Where
- 2 sites in Spain
- Volunteers
- 240 people
- Sponsor
- Chiesi España, S.A.U.
Lung Transplantation, Extracorporeal Membrane Oxygenation (ECMO)
Prospective Observational Pilot Study of LMWH Versus UFH as ECMO Anticoagulation in Lung Transplantation
The aim of this observational pilot study is to evaluate the effectiveness and safety of low-molecular-weight heparin (LMWH) compared to unfractionated heparin (UFH) as anticoagulation in perioperative ECMO during bilateral lung…
- Conditions
- Lung Transplantation, Extracorporeal Membrane Oxygenation (ECMO), Anticoagulants and Bleeding Disorders
- Trial name
- LUX-ET-LT (NCT06868823)
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- University Hospital, Motol
Lung Transplantation
Transplanting Lungs From Uncontrolled Donation After Circulatory Death
The study team developed an uncontrolled donation after circulatory death (uDCD) protocol that preserves lungs for just over 3 hours after death using positive end expiratory pressure (PEEP) and supplemental oxygen.
- Trial name
- NCT06327945
- Testing
- Lung uDCD Protocol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Microplastics, Lung Cancer (NSCLC)
Microplastics in the Human Respiratory System
Environmental pollution from plastics has become a significant global issue, with microplastics-tiny particles resulting from plastic degradation-being increasingly detected in various environments, including aquatic ecosystems…
- Conditions
- Microplastics, Lung Cancer (NSCLC), Lung Transplantation
- Trial name
- NCT06603675
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Cytomegalovirus Infections, Heart Transplantation
Quantiferon CMV to Identify Treatment Need for Asymptomatic CMV Infection After Solid Organ Transplant (QUANTIFOT)
Context Cytomegalovirus (CMV) infection is a frequent and potentially severe event in solid organ transplant (SOT) recipients. Most of available treatment display adverse effects that limit their use.
- Conditions
- Cytomegalovirus Infections, Heart Transplantation, Kidney Transplantation, Lung Transplantation
- Trial name
- QUANTIFOT (NCT06341543)
- Testing
- Quantiferon CMV (assay that determine the presence of CMV-specific T lymphocytes)., Communication of the result of the QF-CMV to the clinician in charge
- Where
- France
- Volunteers
- 288 people
- Sponsor
- University Hospital, Grenoble