Clinical trials: Lung Resection
Non-small Cell Lung Cancer
A Study of SYS6010 Plus Anti-PD-(L)-1 Monoclonal Antibody as Adjuvant Therapy in Non-small Cell Lung Cancer (NSCLC)
The purpose of the study is to compare the efficacy and safety of SYS6010 in combination with anti-PD-(L)-1 monoclonal antibody vs. anti-PD-(L)-1 monoclonal antibody as adjuvant therapy for patients with.
- Trial name
- NCT07672223
- Testing
- SYS6010, Enlonstobart, Tislelizumab
- Volunteers
- 570 people
- Sponsor
- CSPC Megalith Biopharmaceutical Co.,Ltd.
Lung Pathologies of Unclear Etiology
Early Postoperative Day 0 Chest Tube Removal After Thoracoscopic Minor Surgeries
The safe conditions for early chest tube removal have been progressively questioned and redefined around reliable digital air flow criteria and extension of liquid threshold accepted.
- Trial name
- CTremoval (NCT04670523)
- Testing
- Early postoperative day 0 (POD 0) chest tube removal., Chest tube removal according to traditional standard protocol not earlier than on postoperative day 1 (POD 1).
- Where
- Switzerland
- Volunteers
- 304 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Colorectal Cancer, Metastatic Cancer
Flt3L in Treating Patients With Metastatic Colorectal Cancer
RATIONALE: Flt3L may stimulate a person's immune system and help kill tumor cells. PURPOSE: Phase I trial to study the effectiveness of flt3L given to patients before undergoing surgery to remove metastases from colorectal cancer.
- Trial name
- NCT00003431
- Testing
- recombinant flt3 ligand
- Where
- United States
- Sponsor
- Duke University
Post-thoracotomy Pain Syndrome
IMPACT OF OPERATIVE POSITIONING ON THE DEVELOPMENT OF SHOULDER PAIN AFTER PULMONARY LOBECTOMY BY VATS
The investigators want to be able to show a 66% decrease in the incidence of shoulder pain in the "support" group compared to the "suspension" group.
- Trial name
- POVA (NCT04415242)
- Testing
- positioning
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Thoracic Surgery
Comparing of Microcoil Localization and Hook Wire Localization for Resectable Pulmonary Small Nodules
Both of microcoil localization and hookwire localization have been proved as good preoperative CT(computed tomography)-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to…
- Trial name
- NCT02908646
- Testing
- microcoil localization, hookwire localization
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking University People's Hospital
ARDS, Human, Extracorporeal CO2 Removal
ECCO2R - Mechanical Power Study
Although mechanical ventilation remains the cornerstone of ARDS treatment, several experimental and clinical studies have undoubtedly demonstrated that it can contribute to high mortality through the developing of ventilator…
- Conditions
- ARDS, Human, Extracorporeal CO2 Removal, Mechanical Power
- Trial name
- NCT03939260
- Testing
- Extracorporeal CO2 Removal
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Milan
Non-Small Cell Lung Cancer, Adjuvant Therapy
Adjuvant Immune Checkpoint Inhibitor Versus Observation After Neoadjuvant Immunochemotherapy and Surgery in High-Risk NSCLC
This multicenter, randomized, open-label, phase II trial is designed to evaluate the efficacy and safety of adjuvant sintilimab in patients with completely resected non-small cell lung cancer who remain at high risk of recurrence…
- Conditions
- Non-Small Cell Lung Cancer, Adjuvant Therapy, Immune Checkpoint Inhibitors
- Trial name
- RICA (NCT07748325)
- Testing
- Sintilimab
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Sichuan University
Pulmonary Wedge Resection
Small-diameter Closed Thoracic Drainage Tube Fixation Method
Objective: To explore the design feasibility and application effect of triple-buffer-system-fixed small-diameter (18 F) thoracic closed drainage tubes following lung wedge resection.
- Trial name
- NCT05601076
- Testing
- fixed with the triple-buffer system, fixed using the conventional lifting platform method
- Where
- China
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University
Air Leak From Lung
Pneumostasis With Use of Bio-absorbable Mesh and Fibrin Sealant in Lung Resection
Prolonged air leak, defined as air leak present 5 days after lung resection, is one of the most common complications after lung resection.
- Trial name
- NCT04317924
- Testing
- Polyglycolic acid felt, Standard of care
- Where
- United States
- Sponsor
- Boston Medical Center
Non-small Cell Lung Carcinoma
Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour Resection
This is a multicenter, randomized, open label, phase III study.
- Trial name
- APEX (NCT04762459)
- Testing
- Almonertinib, Pemetrexed, Cisplatin
- Where
- 34 sites in China
- Volunteers
- 606 people
- Sponsor
- Chinese Academy of Medical Sciences