Clinical trials: Lung Resection
Thoracic Surgery, Video-Assisted
Two-Lumen Catheterization For Lung Wedge Resection
This study evaluates the viability and safety of two-lumen catheterization versus chest tube placement in patients with lung wedge resection.
- Trial name
- NCT03230019
- Testing
- chest tube, two-lumen catheterization, two-lumen catheter
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Wen-zhao ZHONG
Duct Ectasia Breast, Benign Breast Disease
Central Mammary Duct Excision; How to Improve the Outcome?
the study compares two surgical techniques in excision of the central duct system of the breast. known also as major duct excision
- Trial name
- MDE (NCT04744766)
- Testing
- major duct excision
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Alexandria University
Lung Adenocarcinoma, Frozen Section
Sublobar Resection for Adenocarcinoma in Situ/Minimally Invasive Adenocarcinoma Diagnosed by Intraoperative Frozen Section (ECTOP-1019)
This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1019. The goal of this clinical trial is to confirm the therapeutic effect of sublobar resection for AIS/MIA diagnosed by…
- Conditions
- Lung Adenocarcinoma, Frozen Section, Sublobar Resection
- Trial name
- NCT06031181
- Testing
- Sublobar Resection
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Fudan University
Neoplasm Metastasis, Sarcoma
Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
Background: Most patients who have surgery for cancer that has metastasized (spread) to the lungs later get more metastases that cannot be treated with surgery or chemotherapy.
- Conditions
- Neoplasm Metastasis, Sarcoma, Neoplasms, Germ Cell and Embryonal, Melanoma
- Trial name
- NCT02839694
- Testing
- decitabine (DAC), Tetrahydrouridine (THU), Celecoxib
- Sponsor
- National Cancer Institute (NCI)
Pulmonary Aspergillosis, Surgery-Complications
Uniportal VATS Resection for Pulmonary Aspergilloma : Evaluation of Prognostic Factors in a Single Center Experience
The objective of this study was to report our experience with U-VATS resection and to evaluate our surgical outcomes with an analysis of postoperative complications.
- Conditions
- Pulmonary Aspergillosis, Surgery-Complications, Thoracic Diseases
- Trial name
- NCT06564727
- Testing
- Uniportal VATS approach, VATS approach
- Where
- Morocco
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hassan II University
Lung, Lung Adenocarcinoma
Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs.
- Conditions
- Lung, Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Cancer, Non-Small Cell
- Trial name
- NCT06602661
- Testing
- Fissureless Lobectomy with Reinforced Staple Lines, Fissureless Lobectomy with Non-Reinforced Staple Lines
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Surrey Thoracic Surgery Group
Cancer Metastatic to the Liver, Hepatocellular Carcinoma
A Study to Assess PV-10 Chemoablation of Cancer of the Liver
This open-label study will evaluate the safety, tolerability, pharmacokinetics and effect on tumor growth following a single intralesional injection of PV-10 in subjects with either (a) hepatocellular carcinoma (HCC) that is not…
- Conditions
- Cancer Metastatic to the Liver, Hepatocellular Carcinoma, Metastatic Melanoma, Metastatic Ocular Melanoma
- Trial name
- NCT00986661
- Testing
- PV-10 (10% rose bengal disodium)
- Where
- 5 sites in United States
- Volunteers
- 78 people
- Sponsor
- Provectus Biopharmaceuticals, Inc.
Malignant Neoplasm of Lung
Endobronchial Valves in Persistent Air Leak
Because an endobronchial valve is a one-way inspiratory airway blocker, it is hypothesized that it could be also used for controlling persistent air leaks while maintaining the drainage of secretions. The U.S.
- Trial name
- NCT01451359
- Testing
- EndoBronchial Valve
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Thoracic Diseases, Surgery
Geriatric Thoracic Surgery Ambulation Challenge
This study is examining collecting data on steps walked (ambulation) per day by thoracic surgery patients over the age of 65 years-old before surgery. The name(s) of the study device involved in this study is: Fitbit inspire
- Conditions
- Thoracic Diseases, Surgery, Therapy, Exercise
- Trial name
- NCT04630496
- Testing
- Fitbit
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Lung Nodules, Lung Cancer
The Impact of Thoracic Paravertebral Nerve Block At Different Positions on Pain Relief in Patients Undergoing Single-Port Thoracoscopic Partial Lung Resection
Thoracic surgery is widely recognized as one of the most painful surgical procedures. Compared to open thoracotomy, video-assisted thoracoscopic surgery (VATS) offers similar therapeutic outcomes with less invasiveness…
- Trial name
- NCT06789276
- Testing
- Supine position, lateral decubitus position
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Pneumothorax and Air Leak, Pneumothorax
Urine Bag Usage Versus Chest Drain Clamping After Lung Resection Surgeries
Investigators will compare two different approaches of postoperative drainage after the standard water-seal drain has been used efficiently; one is by using urine bag and check it get blown by the leaked air, two is by using…
- Conditions
- Pneumothorax and Air Leak, Pneumothorax, Pleura Injury, Pleural Effusion
- Trial name
- NCT05230420
- Testing
- Clamping, Urine bag
- Where
- 4 sites in Egypt, Italy and 1 more
- Volunteers
- 160 people
- Sponsor
- Al-Quds University
Exercise Test, Thoracic Cancer
Interest of CPET to Predict Mortality and Complications of Lung Resection Candidates
Anatomic lung resection is the treatment of choice for the management of cancerous lung nodules Non-Small-Cell Lung Carcinoma (NSCLC). Systematic functional evaluation can reduce the risk of mortality and morbidity of candidates.
- Trial name
- NCT05502263
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Pulmonary Nodules, Early-Stage Lung Cancer
CT-Free Electromagnetic Navigation Percutaneous Localization for Pulmonary Nodules Undergoing Sublobar Resection
Pulmonary nodules, particularly small and non-palpable nodules, present challenges for accurate localization during sublobar lung resection.
- Trial name
- NCT07743775
- Where
- 3 sites in China
- Volunteers
- 153 people
- Sponsor
- Jianle Chen
Endotracheal Extubation, Airway Obstruction
Efficacy Study of a Novel Device to Clean the Endotracheal Tube
The purpose of this study is to evaluate the in-vivo efficacy of a novel device (endOclear) for cleaning the endotracheal tube (ETT) lumen from secretions.
- Conditions
- Endotracheal Extubation, Airway Obstruction, Airway Control, Pneumonia, Ventilator-Associated
- Trial name
- NCT01765530
- Testing
- ETT cleaning maneuver
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Massachusetts General Hospital
Non-Small Cell Lung Cancer
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)
The optimal treatment for Stage I or Stage IIA non-small cell lung cancer (NSCLC) remains controversial. Radiographic surveillance alone has been recommended for stage I and stage IIA patients after the tumor is removed…
- Trial name
- NCT01817192
- Testing
- Adjuvant Chemotherapy, Radiographic surveillance, 14-Gene Prognostic Assay
- Where
- 49 sites in United States, France and 1 more
- Volunteers
- 420 people
- Sponsor
- Razor Genomics
Carcinoma, Non-Small-Cell Lung, Neoadjuvant Immunotherapy
Comparison of the Effect of Surgical Resection Based on Lesion Extent Before and After Neoadjuvant Therapy in Patients With Stage II-IIIB Non-Small Cell Lung Cancer: A Single-Center, Real-World, Open-Label Study
This study intends to conduct a prospective, non-interventional study to compare the survival benefits of different surgical resection patterns for patients with non-small cell lung cancer who have achieved partial response (PR)…
- Conditions
- Carcinoma, Non-Small-Cell Lung, Neoadjuvant Immunotherapy, Surgery
- Trial name
- NCT07373899
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Lung Diseases
Image - Navigated Resection of Lung Nodules
This is an open label study lung nodules that are either cancer or non-cancer and who are eligible for surgical resection. Patients will undergo their surgery with the help of the Lung Resection Marker Locator Kit which will…
- Trial name
- NCT04702165
- Testing
- lung resection with Lung Resection Marker Locator Kit
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Navigation Sciences, Inc.
Air Leak From Lung
Hemopatch Compared to TachoSil in Postoperative Air Leak Duration After Pulmonary Resection
This study is a randomized, controlled study, with the primary objective to demonstrate non-inferiority of Hemopatch compared to TachoSil in postoperative air leak duration after pulmonary resection, and with the secondary…
- Trial name
- NCT03450265
- Testing
- Hemopatch, Tachosil
- Where
- 14 sites in Italy, Spain
- Volunteers
- 279 people
- Sponsor
- Baxter Healthcare Corporation
Thoracic Neoplasms, Non-small Cell Lung Cancer
Postoperative Radiotherapy for Patients With IIIA (N2) Non-small Cell Lung Cancer
Several important international randomized trials have shown that postoperative chemotherapy contributed to the improvement on 5 year survival rate by about 4% for patients with non-small cell lung cancer (NSCLC) after complete…
- Trial name
- NCT00880971
- Testing
- Postoperative 3D-CRT or IMRT
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Chinese Academy of Medical Sciences
Carcinoma, Non-Small-Cell Lung
Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)
The primary purpose of this study is to demonstrate Pharmacokinetic similarity in exposure after the initial dose and at steady state of QL2107 compared with Keytruda.
- Trial name
- NCT07162883
- Testing
- QL2107, Keytruda®
- Where
- 84 sites in Bosnia and Herzegovina, China and 11 more
- Volunteers
- 146 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.