Clinical trials: Lung Recruitment
Mechanical Power, Alveolar Recruitment Maneuvers
The Role of Periodic Alveolar Recruitment Maneuvers in Intraoperative Protective Ventilation
The goal of this clinical trial is to compare three open-lung strategies on respiratory function and lung injury in protective ventilation for laparoscopic anterior resection.
- Conditions
- Mechanical Power, Alveolar Recruitment Maneuvers, Protective Ventilation, Postoperative Pulmonary Complications
- Trial name
- REMAIN-2 (NCT05962125)
- Testing
- periodic alveolar recruitment maneuvers, positive end-expiratory pressure
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Anesthesia, Perioperative/Postoperative Complications
Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
This is an observational, prospective, single-centre study that will focus on patients undergoing major non-cardiac surgery requiring invasive mechanical ventilation and invasive blood pressure monitoring Hypotheses: A positive…
- Conditions
- Anesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic Instability
- Trial name
- HiPEEP (NCT06123039)
- Testing
- Tidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Atelectasis
Lung Recruitment Improves Right Ventricle Performance
This study test whether a lung recruitment maneuver improves the right ventricle performance after cardiopulmonary bypass. Half of the patients received an standard protective ventilation and the other half the same ventilatory…
- Trial name
- NCT02795208
- Testing
- Lung recruitment maneuver
- Volunteers
- 40 people
- Sponsor
- Hospital Privado de Cordoba, Argentina
Pneumoperitoneum, Recruitment
Effect Low Pressure Pneumoperitoneum and Pulmonary Recruitment on Postoperative Pain
The investigators want to test the hypothesis that the addition of a recruitment manoeuvre to a low pressure pneumoperitoneum will lead to an additional reduction in postoperative pain.
- Conditions
- Pneumoperitoneum, Recruitment, Postoperative Pain
- Trial name
- NCT03069586
- Testing
- Pulmonary recruitment, No pulmonary recruitment
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- General Hospital Groeninge
ARDS: Acute Respiratory Distress Syndrome
Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS)
In this study gas-exchange and respiratory mechanics variations to PEEP change will be correlated to CT lung morphological modifications assessed at different airway pressures (5, 15, 30 and 45 cmH2O).
- Trial name
- NCT01670747
- Testing
- Chest computed tomography
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Policlinico Hospital
ARDS, Human
Optimal PEEP Titration Combining Transpulmonary Pressure Measurement and Electric Impedance Tomography
Diagnosis and treatment of the hypoxic respiratory failure induced by severe atelectasis with the background of acute lung injury is challenging for the intensive care physicians.
- Trial name
- NCT04174014
- Testing
- Recruitment manoeuvre
- Where
- Hungary
- Volunteers
- 10 people
- Sponsor
- Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
Mechanical Ventilation Complication, Surgery
a Bayesian Analysis of Three Randomised Clinical Trials of Intraoperative Ventilation
The investigators designed a protocol for a Bayesian unplanned posthoc analysis using the pooled dataset from three large randomized clinical trials.
- Conditions
- Mechanical Ventilation Complication, Surgery, Pulmonary Complication, Postoperative Complications
- Trial name
- NCT05886387
- Testing
- High PEEP + Recruitment maneuvers, Standard PEEP. Low positive end-expriatory pressure
- Where
- 4 sites in Brazil, Italy and 2 more
- Volunteers
- 3,836 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV)
Individualized Open Lung Ventilation and Postoperative Pulmonary Complications in Thoracic Surgery
This prospective, single-center, randomized controlled trial aims to evaluate the efficacy of an intraoperative "Individualized Open Lung Ventilation" strategy compared to a standard lung-protective ventilation strategy in…
- Conditions
- Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV), Thoracic Surgery, Video Assisted
- Trial name
- NCT07387822
- Testing
- Standard Lung-Protective Ventilation, Individualized Open Lung Ventilation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Aerospace Center Hospital
Atelectasis, Perioperative Oxygenation
Individualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia Surgery
During laparoscopic surgery under general anesthesia, lung function can be affected by increased abdominal pressure and patient positioning.
- Conditions
- Atelectasis, Perioperative Oxygenation, Laparoscopic Inguinal Hernia Repair, Mechanical Ventilation
- Trial name
- NCT07775573
- Testing
- Standard PEEP Ventilation, Individualized PEEP Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Hypoxia
Trans Alveolar Pressure Measurement as an Index for Lung Recruitment.
the study is conducted on hypoxic adult patients underwent open heart surgery after arrival to the intensive care unit and stabilization of patients' hemodynamics to assess the efficacy of transalveolar pressure measurement as an…
- Trial name
- NCT04168151
- Testing
- lung recruitment protocol
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- University of Alexandria
ASA Class I/II Patients Scheduled for Surgery Under General Anesthesia, Laparoscopic Hysterectomy
THE EFFECT OF ALVEOLAR RECRUITMENT MANOEUVRE ON INTRAOPERATIVE HAEMODYNAMICS
Alveolar recruitment manoeuvre plays a key role in the prevention of atelectasis. In addition, it affects haemodynamic parameters.
- Trial name
- NCT07299396
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Balikesir University
Lung Cancer Requiring Surgical Resection Under One-lung Ventilation
Effect of Bilateral vs. Unilateral Alveolar Recruitment on Gas Exchange in Lung Resection
"One-lung ventilation (OLV) is an essential technique during thoracic surgery but preventing atelectasis during OLV remains a key challenge in thoracic anesthesia.
- Trial name
- NCT07044661
- Testing
- Unilateral ARM, Bilateral ARM
- Where
- 2 sites in South Korea
- Volunteers
- 198 people
- Sponsor
- Yonsei University
Bariatric Surgery, Obesity, Morbid
Lung Recruitment Manoeuvre in Morbidly Obese Patients Underdoing Laparoscopic Bariatric Surgery
Lung ultrasonography is an easy-to-use, portable, non-invasive, visual, and non-radiative technique that has been widely used in clinical monitoring and diagnosis.
- Trial name
- NCT06000969
- Testing
- Lung Recruitment Conventional, Lung Recruitment Ultrasound
- Where
- 2 sites in Egypt
- Volunteers
- 78 people
- Sponsor
- Tanta University
Nitric Oxide, Acute Respiratory Distress Syndrome
Potential for Inhaled Nitric Oxide and Ventilation-Perfusion Mismatch by Electrical Impedance Tomography in the ARDS Patients With Lung Recruitment
In the recent years, the treatment of Acute Respiratory Distress Syndrome has been proved that lung recruitment re-opens the non-ventilated alveolar to improve ventilation, and inhaled Nitric Oxide dilates non-perfused pulmonary…
- Trial name
- NCT04776408
- Testing
- Lung recruitment combined inhaled Nitric oxide, Lung recruitment
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Ventilator Induced Lung Injury, Cardiac Disease
Intensive Alveolar Recruitment Protocol After Cardiac Surgery
The purpose of this study was to evaluate prospectively the impact of two protective mechanical ventilation strategies, both using low tidal volume ventilation (6 mL/kg/ibw) after cardiac surgery.
- Conditions
- Ventilator Induced Lung Injury, Cardiac Disease, Acute Lung Injury
- Trial name
- NCT01502332
- Testing
- Intensive Alveolar Recruitment, Moderate Alveolar Recruitment
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- University of Sao Paulo
Cerebral Injuries, Acute Respiratory Distress Syndrome (ARDS)
Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation
This study aims to compare 2 alveolar recruitment maneuvers (ARM) in patients with cerebral injuries and acute respiratory distress syndrome (ARDS) in term of efficacy and tolerance.
- Trial name
- M'RHICO (NCT02574169)
- Testing
- alveolar recruitment maneuvers group 1, alveolar recruitment maneuvers group 2
- Where
- 5 sites in France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse
ARDS
Effectiveness of Recruitment Maneuvers and Lung Protective Ventilation Strategy in ARDS
The study was designed to comparison the effectiveness of recruitment maneuvers(RM) and lung protective ventilation strategy(LPVS) for patients with moderate to severe ARDS.
- Trial name
- ARDS (NCT05023226)
- Testing
- RM, LPVS
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Asia University