Clinical trials: Lung Cancer Screening
Lung Cancer, Non-Small Cell, Lung Cancer Small Cell Lung Cancer (SCLC)
SERS-Based Serum Molecular Spectral Screening for Lung Cancer Type
Lung cancer can be divided into two major categories: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), with NSCLC accounting for about 85% and SCLC about 15%.
- Trial name
- NCT06775002
- Testing
- Serum Raman spectroscopy intelligent diagnostic system
- Volunteers
- 223 people
- Sponsor
- Fuzhou General Hospital
Cancer, Lung Cancer
The SUMMIT Study: A Cancer Screening Study
The SUMMIT Study will enrol 13,000 participants in order to investigate how cancer screening can be improved and delivered. The SUMMIT Study has two main aims: the first is to clinically validate a blood test for detecting…
- Trial name
- SUMMIT (NCT03934866)
- Testing
- Low Dose CT scan
- Where
- United Kingdom
- Volunteers
- 13,035 people, healthy volunteers welcome
- Sponsor
- University College, London
Lung Cancer
Dissemination Of Lung Cancer Screening Education Through Tobacco Quitlines
The goal of this research study is to compare two different ways to increase lung cancer screening rates for tobacco quitline clients.
- Trial name
- NCT07720141
- Testing
- High-touch strategy
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Carcinoma
Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer
This clinical trial investigates how practical and doable (feasibility) cell-free deoxyribonucleic acid (DNA) liquid biopsy is in screening high-risk patients for lung cancer.
- Trial name
- NCT05384769
- Testing
- Liquid Biopsy, Low Dose Computed Tomography of the Chest, Survey Administration
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Prostate, Brain
Evaluation for NCI Radiation Oncology Branch Clinical Research Protocols
Background: -This protocol will provide a means for screening potential candidates for NCI Radiation Oncology Branch (ROB) protocols.
- Conditions
- Prostate, Brain, Breast, Lung
- Trial name
- NCT00026689
- Where
- United States
- Volunteers
- 903 people
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer, Pulmonary Nodule
Exhaled Breath Electronic Nose for Multi-Disease Risk Prescreening
This prospective multicenter observational study will evaluate whether an electronic nose that analyzes patterns in exhaled breath can be developed as a noninvasive tool for early risk prescreening across several disease areas.
- Conditions
- Lung Cancer, Pulmonary Nodule, Chronic Respiratory Disease, Metabolic Disease
- Trial name
- BREATH-PAN (NCT07804017)
- Testing
- Electronic-Nose Breath Assessment
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Lung Cancer
Retrospective Epidemiological Study of Lung Cancer With Low-dose Multislice Computed Tomography
Lung cancer is one of the leading causes of cancer-related death in Taiwan. Early diagnosis of lung cancer may improve cancer survival.
- Trial name
- NCT02736643
- Volunteers
- 1,334 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lung Cancer Screening, Lung Neoplasms
Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)
Lung cancer screening (LCS) with low-dose computed tomography (LDCT) can reduce the risk of dying from lung cancer, but many people who are eligible for screening do not receive it.
- Conditions
- Lung Cancer Screening, Lung Neoplasms, Smoking ( Cigarette), Early Detection of Cancer
- Trial name
- Empower LCS+ (NCT07711691)
- Testing
- Empower LCS, Call+ Telephone Navigation, Usual Care
- Where
- 57 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine
Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)
This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery.
- Conditions
- Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8
- Trial name
- NCT02194738
- Testing
- Biospecimen Collection, Carboplatin, Cisplatin
- Where
- 1,660 sites in United States, Guam and 1 more
- Volunteers
- 7,458 people
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer
Exhaled Breath Biomarkers in Lung Cancer
Analysis of volatile organic compounds (VOCs) is a new attractive non-invasive field in medical diagnostics. These VOCs can be detected via the exhaled breath.
- Trial name
- NCT01386203
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Lung Cancer, Peripheral Vascular Diseases
Peripheral Vascular Disease as a Clinical Trigger for Opportunistic Lung Cancer Screening Referral: An Implementation Study
The study aims to determine whether patients with peripheral vascular disease who attend the vascular clinics are eligible for lung cancer screening.
- Conditions
- Lung Cancer, Peripheral Vascular Diseases, Ankle Brachial Index, Low Dose Computed Tomography
- Trial name
- PVD-Lungs (NCT07598279)
- Testing
- Observational - low dose computed tomography scan, Experimental - low dose computed tomography scan
- Where
- India
- Volunteers
- 355 people
- Sponsor
- International Agency for Research on Cancer
Lung Cancer
Increasing Equity in Lung Cancer Screening
The overall objective of this mixed methods study is to: 1) Refine the Emergency Department Lung Cancer Screening (ED-LCS) intervention using qualitative interviews among key stakeholders; 2) pilot test the ED-LCS intervention…
- Trial name
- LUCARE (NCT06360822)
- Testing
- ED-LCS
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Indiana University
Lung Cancer Screening
Lung Cancer Screening for Early Detection of Suspicious Lung Nodules in Latin America(LUCAS-LATAM)
Prospective study to assess lung cancer screening with low dose CT scan (LDCT) in Latin America (LATAM) and prospectively evaluate chest-XRay analyzed with artificial intelligence (AI) using qXRin (QURE ai) at the initial visit…
- Trial name
- LUCAS-LATAM (NCT07524803)
- Testing
- Chest X-Ray, Low Dose CT scan
- Where
- 2 sites in Colombia, Costa Rica
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Latin American Consortium for the Lung Cancer Research
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization
This study evaluates whether multiparametric chest magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), performed without any contrast material, can distinguish malignant from benign lung lesions that were…
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Lung Neoplasms, Lung Cancer Screening
- Trial name
- NCT07768046
- Testing
- Multiparametric chest MRI with diffusion-weighted imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Lung Cancer
Tribally Engaged Approaches to Lung Screening (TEALS)
Lung cancer is the leading cause of cancer mortality among American Indians and Alaska Natives (AI/AN), and AI/AN have worse lung cancer incidence rates, survival, and death compared to the general population.
- Trial name
- TEALS (NCT04948060)
- Testing
- Enhanced lung cancer screening services
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma