Clinical trials: Lumbar Stenosis
Lumbar Spinal Stenosis With Bilateral Lower Extremity Radiculopathy
Effect of Skin Stretching on Pain Reduction During Local Anesthetic Injections: A Randomized Clinical Study
The purpose of this study is to investigate the potential analgesic effect of skin stretching during local anesthetic injection in patients with chronic lumbar pain and bilateral lower extremity radiculopathy undergoing selective…
- Trial name
- NCT06976580
- Testing
- conventional local anesthetic injection, skin stetching technique for local anesthetic injection
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Yonsei University
Degenerative Lumbar Spine Diseases, Lumbar Degenerative Disc Disease
Kore Fiber PLF Study
This is a prospective, randomized controlled trial evaluating Kore Fiber® versus autograft in adults undergoing posterolateral lumbar fusion (PLF).
- Conditions
- Degenerative Lumbar Spine Diseases, Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT07868510
- Testing
- Kore Fiber, Autologous bone graft
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Kolosis Bio, LLC
SPINAL Fracture, Vertebral Fractures
Clinical Study With a Robotic Assistant in Patients Requiring a Spinal Transpedicular Fixation
This multicenter, non-comparative clinical trial, led by two principal investigators in Spain, aims to evaluate the safety and performance of a robotic assistant, based on a electromechanical tracking system, in patients…
- Conditions
- SPINAL Fracture, Vertebral Fractures, Spinal Stenosis, Kyphosis
- Trial name
- NCT06153511
- Testing
- Robot assisted spinal transpedicular fixation
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- Cyber Surgery S.L.
Lumbar Radiculopathy, Lumbar Disc Herniation
Prediction of TEI Success in Sciatica
Rationale: Treatment with transforaminal epidural injections is part of usual care in patients suffering from lumbar radiculopathy.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- POTEISS (NCT04540068)
- Testing
- Transforaminal Epidural Injection
- Where
- Netherlands
- Volunteers
- 388 people
- Sponsor
- Eduard Verheijen
Spinal Stenosis
The Coflex®COMMUNITY Study: An Observational Study of Coflex® Interlaminar Technology
The purpose of the coflexCOMMUNITY observational study is to collect information on patients with spinal stenosis undergoing back surgery with the coflex® implant, and to look at their outcomes and the cost-effectiveness of this…
- Trial name
- NCT02457468
- Testing
- coflex
- Where
- 28 sites in United States
- Volunteers
- 325 people
- Sponsor
- Predicted, Reported and Observed Outcomes Foundation
Low Back Pain, Degenerative Condition, Neurologic
Study of the Relation Between the Fat Infiltration of the Multifidus Muscle and the Lumbar Foraminal Stenosis, by 2D and 3D Segmentation
The aim of this study is to evaluate the correlation between the fat infiltration of the lumbar multifidus muscle and several parameters including the severity of the lumbar foraminal stenosis.
- Trial name
- FIMFos (NCT06018155)
- Testing
- Spine surgery
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis
Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
Appropriate fluid management is an important part of anesthesia in patients undergoing surgery, and several dynamic indices have been suggested to have high predictability for fluid responsiveness in patients receiving mechanical…
- Conditions
- Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Scoliosis or Tumors
- Trial name
- NCT02826889
- Testing
- Philips Intelivue MP70 monitor, Pleth Variability Index (PVI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
LUMBAR STENOSIS
Surgical Decompression Associated With Physical Therapy and Physical Therapy Isolated in Patients With Lumbar Stenosis.
Stenosis of symptomatic lumbar canal is presented as a series of degenerative changes affecting the various vertebral segment structures, including: a joint zigoapofisária, yellow ligament, the articular capsule and the…
- Trial name
- Stenosis (NCT02879461)
- Testing
- LUMBAR DESCOMPRESSION
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Federal University of São Paulo
Radiculopathy, Lumbar Disc Herniation
The Effect of Combination of Ultrasound and Flouroscopy Guidance in Caudal Epidural Injections
The primary purpose of this study is to asses the effect of caudal epidural injection guided by a combination of ultrasound and fluoroscopy on the duration of the procedure and the amount of radiation exposed during the…
- Conditions
- Radiculopathy, Lumbar Disc Herniation, Spinal Stenosis
- Trial name
- NCT05145842
- Testing
- floroscopy, ultrasound+fluoroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Degenerative Lumbar Spinal Stenosis
Effectiveness and Safety of the Facet Fixation (FFX®) Implant in the Treatment of Degenerative Lumbar Spinal Stenosis
This is a prospective, multicentric, comparative, randomised-controlled study to evaluate the safety and efficacy of the Facet Fixation implant.
- Trial name
- FFX® RCT (NCT06106061)
- Testing
- Decompression + FFX®, Decompression alone
- Volunteers
- 320 people
- Sponsor
- SC Medica
Lumbar Spinal Stenosis
Role of Spinal Load in the Pathophysiology of Lumbar Spinal Stenosis
This study is to improve the understanding of the role of postural and ambulatory biomechanics for symptoms in patients with sLSS and to correlate patient-reported outcome measures (PROMs) with dynamic compensation (difference…
- Trial name
- RoLSSroice (NCT05523388)
- Testing
- Collection of health-related data
- Where
- Switzerland
- Volunteers
- 122 people
- Sponsor
- University Hospital, Basel, Switzerland
Lumbar Spinal Stenosis (LSS)
Association Between Lumbar Muscle Atrophy, Sagittal Pelvic Alignment and Stenosis Grade in Patients With Degenerative Lumbar Spinal Stenosis
This study is to evaluate the correlation between muscle atrophy (MA), sagittal alignment, and stenosis degree in patients with lumbar spinal Stenosis (LSS).
- Trial name
- AtrophyLSS (NCT04444739)
- Testing
- radiographic data collection
- Where
- Switzerland
- Volunteers
- 165 people
- Sponsor
- University Hospital, Basel, Switzerland
Lumbar Spinal Stenosis, Spinal Instability
Flexion-Extension Radiograph Imaging Protocol Reliability Study
Orthopedic surgeons often face the dilemma of whether to add fusion to a decompression procedure of the spine. Their decision mainly relies on personal experience to determine if a level is unstable preoperatively or if a…
- Trial name
- NCT05633550
- Testing
- Flexion-extension radiographs
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Assessing Superion Clinical Endpoints vs. Decompression
PURPOSE: The primary purpose of this study is to demonstrate that the Composite Clinical Success of the study group receiving the Superion® IDS is not inferior to the success rate observed in the study group treated by direct…
- Trial name
- ASCEND (NCT03048955)
- Testing
- Superion® IDS, Direct decompression Surgery
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VertiFlex, Incorporated
Lumbar Spinal Stenosis
Lumbar Stenosis Outcomes Research (LUSTOR)
The primary objective of the proposed pilot study is to determine the efficacy of pregabalin in prolonging the time to onset of pain and reducing the severity of pain associated with walking in patients with neurogenic…
- Trial name
- LUSTOR (NCT00638443)
- Testing
- Pregabalin, Diphenhydramine
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Rochester
Spinal Stenosis Lumbar
Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis
Lumbar Spinal Stenosis (LSS) is a syndrome characterized by anatomical narrowing of the central canal, lateral recess, or intervertebral foramen of the lumbar spine, leading to compression of nerve roots, the cauda equina, and…
- Trial name
- NCT07482826
- Testing
- Full-Endoscopic Decompression, Endoscopic Lumbar Interbody Fusion
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Degenerative Lumbar Canal Stenosis
Comparison Between The Results of Open and Microsurgical Decompression in Degenerative Spinal Canal Stenosis in Lumbar Spine
To compare the outcomes of open and microsururgical decompression in degenerative spinal stenosis in lumbar spine
- Trial name
- NCT06722859
- Testing
- Open surgical decompression in degenerative lumbar canal stenosis, Microsurgical decompression
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Stenosis
The Impact of Spinal Manipulation on Leg Movement in Lumbar Spinal Stenosis Patients
The objectives of the proposed research are to quantify the impact on motor performance of a single SM intervention on surgical waitlist patients with degenerative Lumbar Spinal Stenosis (LSS) using a recently established lower…
- Trial name
- NCT02118103
- Testing
- Spinal Manipulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Spinal Fusion Acquired, Spinal Stenosis
Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion
Major lumbar spine surgery causes inflammation, soreness and swelling that can delay discharge from the hospital. Dexmedetomidine (DEX) has been shown to have anti-inflammatory effects.
- Conditions
- Spinal Fusion Acquired, Spinal Stenosis, Lesions of Lumbosacral Intervertebral Disc, Spinal Diseases
- Trial name
- DEXREDLOS (NCT00808665)
- Testing
- Dexmedetomidine, 0.9% Saline
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Vanderbilt University Medical Center
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb
Cost Effectiveness of OMT for Chronic Low Back Pain
The specific aim of this study is to conduct a prospective, multicenter cohort study over four months to compare the cost of standard of allopathic care (control group, N=90) versus standard of care plus osteopathic manipulative…
- Conditions
- Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis
- Trial name
- NCT03532230
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Rowan University