Clinical trials: Lumbar Pain Syndrome
Myofascial Pain Syndrome
A Multiple Component Mobile-aid Pain Reduction Intervention to Decrease Myofascial Pain
The goal of this clinical trial is to pilot test a newly developed multiple component mobile-aid pain reduction intervention (MCMAPRI) and the feasibility of implementing this intervention in adult patients with myofascial pain…
- Trial name
- NCT05860205
- Testing
- Multiple Component Mobile-Aid Pain Reduction Intervention, Osteopathic Manipulation Treatment
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kailea Manning
Low Back Pain, Patient Acceptance of Health Care
Veterans Response to Dosage in Chiropractic Therapy
This study evaluates how Veterans with chronic low back pain (cLBP) respond to varying doses of chiropractic therapy and how health services utilization are impacted as a result. There are 2 phases in this study.
- Conditions
- Low Back Pain, Patient Acceptance of Health Care, Veterans Health
- Trial name
- VERDICT (NCT04087291)
- Testing
- Chiropractic Care
- Where
- 4 sites in United States
- Volunteers
- 766 people
- Sponsor
- Palmer College of Chiropractic
Failed Back Surgery Syndrome, SCS
Spinal Cord Stimulation Versus Instrumentation for FBSS
Low back pain affects people of all ages and has become the leading cause of living with disability worldwide. Patients, suffering from persistent pain after spinal surgery in the absence of any clear spinal pathology are defined…
- Conditions
- Failed Back Surgery Syndrome, SCS, Neuromodulation, Spinal Cord Stimulation
- Trial name
- PROMISE (NCT05466110)
- Testing
- Spinal Cord Stimulation, Spinal Fusion Surgery
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- University Hospital Augsburg
Lower Crossed Syndrome
Effects of Clamshell Versus Gluteal Bridge Exercises
Gluteal amnesia is a "condition" where the individual is believed to have lost the ability to contract their gluteal muscles - generally the gluteus maximus, though some report it as the gluteus medius.
- Trial name
- NCT05973695
- Testing
- clamshell exercise, Gluteal Bridge exercises
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Lumbosacral Radicular Syndrome
PRF Treatment for Patients With Chronic Lumbosacral Radicular Pain Compared to Conventional Medical Management
The purpose of the study is to evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic lumbosacral radicular syndrome (LRS).
- Trial name
- NCT00991237
- Testing
- Pulsed Radiofrequency
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Back Pain
Comparison of Intraspinal Nerve Root Stimulation With Dorsal Column Stimulation
This study will systematically evaluate the programming parameters of the Precision Spinal Cord Stimulation Device to optimally relieve pain while minimizing any uncomfortable side effects.
- Trial name
- NCT00370773
- Testing
- Precision Spinal Cord Stimulation System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Scientific Corporation
Chronic Pain, Lumbar Pain Syndrome
BioWave High-frequency Neurostimulation Versus TENS for the Treatment of Chronic Low Back Pain
This will be a multicenter randomized crossover clinical trial comparing the therapeutic efficacy of BioWave therapy versus TENS for the management of chronic low back pain.
- Conditions
- Chronic Pain, Lumbar Pain Syndrome, Low Back Pain
- Trial name
- BioWave (NCT05511181)
- Testing
- BioWave, TENS
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- BioWave Corporation
Chronic Low Back Pain, Depression
Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.
- Trial name
- NCT06419439
- Testing
- Ketamine hydrochloride, Minimally Enhanced Usual Care, Brief narrative intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Trigger Point Pain, Myofascial
Comparison of Myofascial Release Technique and Instrument Assisted Soft Tissue Mobilization in Lumbar Region
Trigger point are hyper-irritable points, appear as nodules on palpation, discrete and focal spots in the taut band of skeletal muscles.
- Trial name
- NCT05158556
- Testing
- Myofascial Release Technique, Instrument Assisted Soft tissue Mobilization
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Chronic Low-back Pain, Hip Impairments
Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Older adults with chronic low back pain (LBP) are at a greater risk for disability, loss of independence, and lower quality of life.
- Conditions
- Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
- Trial name
- MASH (NCT04009837)
- Testing
- Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Delaware
Superior Cluneal Nerve Entrapment
Treatment of Upper Cluneal Nerve Entrapment Syndrome for Reduction of Low Back Pain
Superior cluneal nerve entrapment (SCN) is a painful symptomatic condition related to compression by the thoracolumbar and gluteal bands of nerve outcrop, above the iliac crest.
- Trial name
- NCT06059612
- Testing
- injection
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Istituto Ortopedico Rizzoli
Piriformis Syndrome
Comparative Presence of Piriformis Syndrome in Patients With Lumbar Disc Bulging and Protrusion
Clinicians consider lumbar disc herniation more prominently in the differential diagnosis than piriformis syndrome, as it is the most common cause of sciatica, and this canalizes them to overlook that the sciatic nerve may be…
- Trial name
- NCT06435169
- Testing
- Lasegue's, Freiberg's and, FAIR (Flexion Adduction Internal Rotation) tests.
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Yuzuncu Yil University
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Chronic Low Back Pain
Aging Back Clinics
The purpose of this study is to compare two different ways to treat chronic low back pain. The two types of treatment that the investigators will compare are called Usual Care and ABC Care. Usual Care tends to focus on the spine.
- Trial name
- NCT03564600
- Testing
- Aging Back Clinics management
- Where
- 3 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Musculoskeletal Disorders, Musculoskeletal Pain
The Efficacy of Ergonomic Intervention in Preventing Musculoskeletal Disorders Among Women After Giving Birth
The woman's body undergoes many physiological changes during pregnancy, which can cause muscle weakness and postpartum joint instability.
- Conditions
- Musculoskeletal Disorders, Musculoskeletal Pain, Post Partum
- Trial name
- NCT04244279
- Testing
- Ergonomic workshop, Brochure, Videos
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Low Back Pain, Chronic
A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain
A research study is being conducted to compare two treatments for long-term low back pain: One uses the iovera° system, which applies cold to certain nerves in the lower back.
- Trial name
- NCT07214844
- Testing
- Iovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Montefiore Medical Center
Low Back Pain, Low Back Pain, Recurrent
Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing
Although the cause of persistent non-specific low back pain (LBP) remains unknown, structural and functional alterations of the brain, alterations in the lumbar muscles and dysfunction of the central nervous system have been…
- Conditions
- Low Back Pain, Low Back Pain, Recurrent, Low Back Pain, Chronic, Healthy Volunteers
- Trial name
- B~Maps (NCT06143319)
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ghent
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median
Chronic Low-back Pain
The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial
The goal of this randomized controlled trial is to compare lumbar interbody fusion surgery with multidisciplinary rehabilitation in participants aged 20-65 years with persisting (≥ one year) low back pain.
- Trial name
- LIFEHAB (NCT06169488)
- Testing
- Lumbar Interbody Fusion, Multidisciplinary rehabilitation
- Where
- 5 sites in Norway
- Volunteers
- 202 people
- Sponsor
- Oslo University Hospital
Diabetic Neuropathic Pain, Chronic Low Back Pain
Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy
The purpose of the study is to determine whether the combination of the the three drugs gabapentin, duloxetine, and donepezil are effective in treating pain in people with diabetic neuropathy or patients with failed low back…
- Trial name
- NCT00619983
- Testing
- donepezil, duloxetine, donepezil 2.5 mg and duloxetine 30mg
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University