Clinical trials: Lower Urinary Tract Disorder
Lower Urinary Tract Symptoms, Neurodevelopmental Disorders
Lower Urinary Tract Symptoms and School Functioning in Children
Children in primary school often suffer from lower urinary tract symptoms (LUTS), which may negatively impact their overall well-being.
- Conditions
- Lower Urinary Tract Symptoms, Neurodevelopmental Disorders, Incontinence, Urinary, ADHD
- Trial name
- NCT06012903
- Testing
- Questionnaire Welbevinden, Questionnaire Vancouver symptom score for dysfunctional elimination syndrome, Developmental Coordination Disorder Questionnaire
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Lower Urinary Tract Symptoms, Voiding Disorders
Comparison of a Paper and Automated Bladder Diary in Pediatric Patients
The purpose of this study is to compare an automated bladder diary (autoBD) to a paper bladder diary (pBD) on their level of agreement, patient compliance and satisfaction. It is a mixed methods, randomized 2x2 crossover trial.
- Conditions
- Lower Urinary Tract Symptoms, Voiding Disorders, Enuresis, Overactive Bladder
- Trial name
- NCT06070675
- Testing
- Minze Diary Pod, Paper bladder diary
- Where
- 5 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Universiteit Antwerpen
Interstitial Cystitis, Chronic Prostatitis
Microbiomes of Pelvic Pain
This research study seeks to provide more insight as to how the microbiome affects or is affected by conditions causing chronic pelvic pain such as Interstitial Cystitis (IC), Chronic Prostatitis/Chronic Pelvic Pain Syndrome…
- Conditions
- Interstitial Cystitis, Chronic Prostatitis, Chronic Pelvic Pain Syndrome, Lower Urinary Tract Symptoms
- Trial name
- NCT01738464
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Overactive Bladder, Urge Incontinence
Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Adults
For overactive bladder symptoms, there are numerous physiotherapy techniques have been found to be beneficial. Transcutaneous electrical stimulation of the tibial nerve is one of those treatment options, that is entirely a…
- Conditions
- Overactive Bladder, Urge Incontinence, Nocturia
- Trial name
- NCT05464589
- Testing
- Transcutaneous tibial nerve stimulation along with pelvic floor muscle srengthening, Pelvic floor muscles strengthening
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Pelvic Floor Disorders, Anxiety
Enhancing Behavioral Treatment for Women With Pelvic Floor Disorders
The purpose of this proposal is to test a novel behavioral treatment - Unified Protocol Cognitive-Behavior Therapy (UP-CBT)1 - to enhance quality of life in women with pelvic floor disorders.
- Conditions
- Pelvic Floor Disorders, Anxiety, Urinary Urgency, Urinary Incontinence
- Trial name
- NCT03623880
- Testing
- Unified Protocol, Supportive Therapy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwestern University
Lower Urinary Tract Symptoms, Voiding Disorders
The Efficacy of Tamsulosin and Tadalafil Compared to Placebo in the Treatment and Prevention of Urinary Disorders After Transperineal Prostate Biopsy
The purpose of this study is to evaluate the therapeutic efficacy of tamsulosin and tadalafil compared to placebo in the treatment and prevention of urinary disorders after transperineal prostate biopsy
- Conditions
- Lower Urinary Tract Symptoms, Voiding Disorders, Pain, Quality of Life
- Trial name
- NCT05537272
- Testing
- Tadalafil 5mg, Tamsulosin Hydrochloride 400 Microgram Prolonged-Release Oral Capsule
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital of Split
Voiding Disorders
Brain Imaging in Men With Lower Urinary Tract Symptoms
Benign Prostatic Hyperplasia (BPH) affects the storage and voiding phases of the micturition cycle. Lower urinary tract symptoms (LUTS) refers to storage symptoms such as urinary frequency, urgency, urge urinary incontinence and…
- Trial name
- NCT03991429
- Testing
- Simultaneous functional MRI and urodynamic studies, Questionnaires, Post Void Residual (PVR), Uroflow and Bladder Diary
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Methodist Hospital Research Institute
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Duchenne Muscular Dystrophy, Lower Urinary Tract Symptoms
Examination of Lower Urinary System Symptoms With Duchenne Muscular Dystrophy
The aim of this study is to examine the prevalence of lower urinary tract symptoms (LUTS) in children with Duchenne Muscular Dystrophy (DMD) and the relationship between functional level, posture, muscle strength, pelvic floor…
- Conditions
- Duchenne Muscular Dystrophy, Lower Urinary Tract Symptoms, Muscle Weakness, Posture Disorders in Children
- Trial name
- NCT05464446
- Testing
- Baseline Bubble Inclinometer, Baseline Digital İnclinometer and Hoggan microFET2 devices
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Lokman Hekim University
Lower Urinary Tract Symptoms, Posture Disorders in Children
Examination of Trunk and Lower Extremity Biomechanics in Children With LUTD.
This study aimed to examine trunk and lower extremity biomechanics among children with lower urinary tract dysfunction (LUTD). It was targeted to pioneer including biomechanical changes into treatment if detected in the trunk and…
- Conditions
- Lower Urinary Tract Symptoms, Posture Disorders in Children, Muscle Weakness Condition, Urinary Incontinence in Children
- Trial name
- NCT05299827
- Testing
- The same evaluation methods were used for both groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Urinary Incontinence, Stress
Autologous Cell Therapy for Stress Urinary Incontinence in Males Following Prostate Surgery
To study the safety and potential efficacy of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR) for the treatment of male stress urinary incontinence (SUI) for patients that have undergone prior prostate…
- Conditions
- Urinary Incontinence, Stress, Urination Disorders, Urologic Diseases
- Trial name
- NCT02291432
- Testing
- autologous muscle-derived cells (AMDC)
- Where
- 5 sites in United States
- Volunteers
- 25 people
- Sponsor
- Cook MyoSite
Fecal Impaction, Lower Urinary Tract Disorder
Development of Fecal Scoring for the Management of Fecal Impaction With Regards to Lower Urinary Tract Dysfunction
The role of bowel bladder disorder, or BBD, has been highlighted as a major player in vesicoureteral reflux and urinary tract infection (UTI).
- Conditions
- Fecal Impaction, Lower Urinary Tract Disorder, Bladder Dysfunction, Bowel Dysfunction
- Trial name
- NCT04579731
- Testing
- Lactitol Monohydrate
- Where
- South Korea
- Volunteers
- 187 people
- Sponsor
- Seoul National University Hospital
Multiple Sclerosis, Lower Urinary Tract Symptoms
Multiple Sclerosis and Voiding Symptoms: How to Assess?
In multiple Sclerosis (MS), storage and voiding symptoms are well described. Urodynamic patterns underlying storage symptoms are clearly defined, but the assessment of voiding phase in neurological diseases is a sensitive topic.
- Conditions
- Multiple Sclerosis, Lower Urinary Tract Symptoms, Voiding Disorders
- Trial name
- NCT04928716
- Testing
- voiding phase evaluation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Pierre and Marie Curie University
Disorder of the Lower Urinary Tract
Changes of microRNA Expression in Obstructive and Neurogenic Bladder Dysfunction
Patients with obstructive or neurogenic lower urinary tract disease will be invited to participate. Upon agreement they will undergo an assessment of bladder function (questionnaires) and bladder biopsies at 2 time-points.
- Trial name
- MoVe (NCT02410876)
- Testing
- Bladder biopsy, Urodynamic study
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lower Urinary Tract Symptoms, Parkinsonism
Effect of Need to Void on Parkinsonian Gait
This study evaluates the effect of the need to void on parkinsonian gait
- Conditions
- Lower Urinary Tract Symptoms, Parkinsonism, Gait Disorders, Neurologic
- Trial name
- NCT03314610
- Testing
- Gait speed
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Pierre and Marie Curie University
Pain, Anxiety
The Effect of Watching Relaxing Video During Cystoscopy
The cystoscopy procedure may cause pain and anxiety in patients. Since cystoscopy causes more pain in men, studies on pain and anxiety during cystoscopy are more common in men than women.
- Conditions
- Pain, Anxiety, Urological Nursing, Lower Urinary Tract Symptoms
- Trial name
- NCT03865459
- Testing
- Video group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Lower Urinary Tract Symptoms, Adjustment Disorders
Lower Urinary Tract Symptoms in Women and Adjustment Disorder
Our hypothesis that the prevalence of AD in uro-gynecologic patients with LUTS who are seeking medical help for their condition is higher than that of the general population (indicated by high scores at the ADNM-20; score above…
- Trial name
- LUTS and AD (NCT03444740)
- Testing
- ICIQ-FLUTS, ADMN-20
- Volunteers
- 100 people
- Sponsor
- Basel Women's University Hospital
Anxiety, Overactive Bladder
Do Patient Anxiety Levels Decrease Urodynamic Test Reproducibility?
This study will look at how pre-test anxiety levels affect the reproducibility of symptoms during routine urodynamic testing in women.
- Conditions
- Anxiety, Overactive Bladder, Urinary Incontinence, Stress, Urinary Incontinence, Urge
- Trial name
- NCT02540798
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Disorder of the Lower Urinary Tract
Studies of Biomarkers in Female Lower Urinary Tract Symptoms
To determine the sensitivity and specificity of urinary NGF, PGE2, IL-6, EGF or combinations in diagnosing different urodynamic diagnoses.
- Trial name
- NCT01681784
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital