Clinical trials: Lower Leg Edema
Surgical Wound, Bilateral Total Knee Arthroplasty
Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA
This study will compare the effects of closed incision negative pressure dressing vs. standard of care silver dressing on lower limb swelling after bilateral primary total knee arthroplasty.
- Conditions
- Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases
- Trial name
- ENABLE (NCT04712019)
- Testing
- Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing
- Where
- 6 sites in United States
- Volunteers
- 10 people
- Sponsor
- Solventum US LLC
Hypertension
A Study to Evaluate Methodologies for Measuring Swelling of the Leg and Ankle (MK-0000-106)(COMPLETED)
This study will evaluate methodologies for measuring pedal edema associated with calcium channel blockers in middle-aged and elderly subjects and patients with hypertension.
- Trial name
- NCT00789321
- Testing
- Comparator: amlodipine besylate
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Edema
Mild Compression Sock for Control of Lower Extremity Edema in Individuals With Diabetes
The purpose of this study is to determine whether a specially designed sock for people with diabetes and swelling in the legs can reduce the swelling, improve blood flow to the legs, and improve physical activity patterns of…
- Trial name
- NCT01529385
- Testing
- mild compression diabetic sock, Standard diabetic sock
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rosalind Franklin University of Medicine and Science
Lymphedema
Lymphedema Study for Arm or Leg Lymphedema
This study compares the effectiveness of a study drug versus placebo in the treatment of lymphedema.
- Trial name
- NCT02257970
- Testing
- Ketoprofen
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Stanford University
Peripheral Edema
Wireless TENS for Peripheral Edema (Lower Limb Swelling)
This study is single center, subject will receive a wireless TENS device. All subjects will be allowed to keep the commercially-available device for use after the study.
- Trial name
- NCT04680533
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Rochester
Diabetes, PAD
Micro-mobile Foot Compression and Diabetic Foot
Diabetic foot ulceration (DFU) is a common and largely preventable complication. While most of these ulcers can be treated successfully, some will persist and become infected.
- Conditions
- Diabetes, PAD, Lower Extremity Edema, Neuropathy;Peripheral
- Trial name
- NCT03135535
- Testing
- Avex Footbeat
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Fluid Overload
Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs
Impact of intraoperative use of pneumatic peristaltic compression device on hemodynamics vis a vis on fluid requirement during general anaesthesia and surgery.
- Trial name
- NCT03789474
- Testing
- HUNTLEIGH FLOWTRON ACS900
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Rishikesh