Clinical trials: Lower Leg Edema
Gynecologic Cancer
Randomized Trial of Exercise on Lower Extremity Edema After Lymphadenectomy in Gynecologic Cancer
The primary outcome is the change in lower extremity edema-related symptoms. Secondary outcomes include the compliance rate of management guidelines for lower extremity edema, the performance rate for pelvic and lower extremity…
- Trial name
- NCT01849224
- Testing
- Pelvic and lower extremity exercise
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- National Cancer Center, Korea
Lower Leg Edema, Orthostatic Hypertension
Observational Study to Evaluate the Safety and Efficacy for Levacalm Tab. Versus Valsartan/Amlodipine Combination Therapy in Essential Hypertension Patients
Levacalm Tab. was approved in Jul 2013 by MFDS in South Korea. Levacalm Tab. is combination drug of Valsartan as an angiotensin II receptor blocker and Lercanidipine as a Calcium channel blocker.
- Trial name
- NCT02415192
- Testing
- Levacalm, Valsartan/amlodipine
- Where
- South Korea
- Volunteers
- 2,001 people
- Sponsor
- LG Life Sciences
Diabetic Foot Ulcer, Pressure Injury
A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System
The purpose of this study is to determine if use of the Medela Invia Motion NPWT system supports acceptable progress towards the goal of therapy when treating patients with a variety of wound types during the evaluation period.
- Conditions
- Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer, Surgical Wound
- Trial name
- NCT04593693
- Testing
- Invia Motion Endure NPWT system
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medela AG
Edema Leg, Compression; Vein
Safety and Efficacy of the ElastiMed's SACS 2.0 - Smart Active Compression Stocking for the Treatment of Venous Edema
Device Efficacy: The primary efficacy assessment will be defined as successful if the edema volume will be reduced over time after using the SACS 2.0 device.
- Trial name
- NCT04837560
- Testing
- ElastiMed's SACS 2.0
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- ElastiMed ltd
Lower Limb Chronic Oedema
Oedema Study : Chroedem
The chroedem study is aiming to assess tissue and biomolecular components of chronic lower limb oedema (CO). The investigators working hypothesis is that according to the aetiology of CO, the proportion of oedema \& composition…
- Trial name
- CHROEDEM (NCT02914808)
- Testing
- Patients will undergo a lower limb MRI and blood tests
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Peripheral Edema
Wireless TENS for Peripheral Edema (Lower Limb Swelling)
This study is single center, subject will receive a wireless TENS device. All subjects will be allowed to keep the commercially-available device for use after the study.
- Trial name
- NCT04680533
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Rochester
Heart Failure; With Decompensation, Lower Extremity Edema
Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.
Heart failure (HF) remains one of the most common causes of hospitalization with high morbidity and mortality, and its worldwide prevalence is increasing.
- Conditions
- Heart Failure; With Decompensation, Lower Extremity Edema, Heart Failure，Congestive
- Trial name
- A-KHALIFE (NCT05467735)
- Testing
- Application of compression to bilateral lower extremities of patients using appropriately-sized elastic compression stockings.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Ankle Sprain
Evaluation of Therapeutic Effects of LED (627 +/- 10nm) The Initial Phase of the Ankle Sprains Treatment
The purpose of this study is to evaluate the therapeutic effects of the LED (627 +/- 10 nm) with respect to the localized pain and local swelling of ankle sprains in the initial phase.
- Trial name
- NCT02433964
- Testing
- Grupo LED
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade do Vale do Paraíba
Edema
Mild Compression Sock for Control of Lower Extremity Edema in Individuals With Diabetes
The purpose of this study is to determine whether a specially designed sock for people with diabetes and swelling in the legs can reduce the swelling, improve blood flow to the legs, and improve physical activity patterns of…
- Trial name
- NCT01529385
- Testing
- mild compression diabetic sock, Standard diabetic sock
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rosalind Franklin University of Medicine and Science
Lymphedema of Leg
Hydrophobic Tubes for the Treament of Lower and Upper Limb Lymphedema
Lymphedema is a chronic condition causing fluid buildup in affected limbs. Traditional treatments often fall short, but subcutaneous implantation of hydrophobic silicone tubes shows promise, creating artificial drainage pathways.
- Trial name
- NCT05970068
- Testing
- implantation of hydrophobic tubes for edema fluid drainage, Best Medical Treatment
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Universidade do Porto
Knee Osteoarthritis, Edema
Control of Edema in the Knee in Patients With Knee Osteoarthritis
The aim of this study was to compare the effectiveness of exercise and classical massage in the control of knee edema in patients with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Edema, Edema Leg
- Trial name
- NCT06010394
- Testing
- conventional physiotherapy, exercises for the knee area, payment oriented massage
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Uskudar University
Anterior Cruciate Ligament Injuries
TCM for Post-operative Edema
There are loads of research on knee surgery, including surgical methods, rehabilitation strategies, and complication prevention.
- Trial name
- NCT06335602
- Testing
- LASER acupuncture
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Pregnancy Complication
Title of the Research: Effect of Manual Lymphatic Drainage Massage Combined With Therapeutic Exercises On Lower Limbs Edema During Late Pregnancy
Objective of the study is to investigate the effect of adding manual lymphatic drainage massage to classical therapeutic exercises on resolving physiological lower limbs edema in late pregnancy women.
- Trial name
- NCT07761741
- Testing
- manual lymphatic drainage massage technique with specific therapeutic exercise
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Ankle Injuries, Fracture
Lymphomyosot for Ankle Edema Following Fracture
Ankle fractures are invariably complicated by severe soft-tissue swelling which can significantly prevent surgical repair (open reduction and internal fixation - ORIF) of the fractured bone for up to two weeks.
- Trial name
- NCT00884988
- Testing
- Lymphomyosot
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Shaare Zedek Medical Center