Clinical trials: Lower Extremity Injuries
Lower Extremity Injury
Improving Recovery After Orthopaedic Trauma: Cognitive-Behavioral Based Physical Therapy (CBPT)
The goal of the CBPT study is to determine the efficacy of the CBPT program for improving outcomes in service members and civilians at-risk for poor outcomes following traumatic lower-extremity injury.
- Trial name
- CBPT (NCT03335657)
- Testing
- CBPT, Education Treatment
- Where
- 8 sites in United States
- Volunteers
- 633 people
- Sponsor
- Major Extremity Trauma Research Consortium
Deep Vein Thrombosis of the Lower Extremities
AI-Based Prediction Model for Iliofemoral DVT Thrombolysis
This prospective single-arm cohort study aims to develop an AI-powered prediction model for treatment outcomes in patients with acute extensive iliofemoral deep vein thrombosis (IF-DVT) undergoing stent-free pharmacomechanical…
- Trial name
- NCT07181083
- Testing
- Rheolytic thrombectomy
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Chronic Ulcer of Lower Extremity, Wound
Effect of Blood Flow by Botulinum Toxin Injection for Severe Peripheral Artery Occlusive Disease
The purpose of this study is to investigate the effect of subcutaneous injection of botulinum toxin A on wound healing caused by lower extremity ischemia.
- Conditions
- Chronic Ulcer of Lower Extremity, Wound, Botulinum Toxins, Type A, Blood Circulation
- Trial name
- NCT06878482
- Testing
- Botulinum toxin A
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Yonsei University
Anterior Cruciate Ligament Injuries, Lower Extremity Problem
Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer
Anterior cruciate ligament (ACL) injuries of the knee are common in youth soccer players, and show an even higher prevalence in female soccer players.
- Trial name
- NCT05442879
- Testing
- Knowledge Translation Intervention, Educational handout
- Where
- United States
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Balance Disorders, Foot Injury
The Effect of Subtalar Joint Pronation Amount on Lower Extremity Alignment and Performance
The lower extremity consists of segments that can be affected by the relative position of each other. Deviation of one segment from its normal alignment in the lower extremity also affects the alignment of other segments.
- Conditions
- Balance Disorders, Foot Injury, Lower Extremity Problem
- Trial name
- NCT06300671
- Testing
- Foot Posture Index-6
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Lower Extremity Problem, Rehabilitation
Patient-Reported Outcome Measures in Lower Extremity Rehabilitation Program PROM_R: Impact on Health Care
Different musculoskeletal conditions affect people all over the world and were considered by the WHO to be the leading cause of disability in 4 out of 6 regions in 2017, with an increase in the associated burden and impact on…
- Conditions
- Lower Extremity Problem, Rehabilitation, Knee Injuries
- Trial name
- PROM_R (NCT06206018)
- Testing
- PROM_R knee rehabilitation program
- Where
- Portugal
- Volunteers
- 65 people
- Sponsor
- University of Évora
Musculoskeletal Injury, Musculoskeletal Strain
Multi-axis Assessment of Injured Workers
The percentage of loss time claims receiving Loss of Earnings benefits at 3 months has continued to rise amongst injured workers in Ontario despite the Workplace Safety and Insurance Board (WSIB) approach of "Better at Work".
- Conditions
- Musculoskeletal Injury, Musculoskeletal Strain, Low Back Pain, Neck Pain
- Trial name
- NCT06016647
- Testing
- Musculoskeletal-specific WSIB programs of care
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- Dave Walton
Chronic Ulcer of Lower Extremity
Healing Rate of Leg Wounds Treated With Contact and Noncontact Ultrasound: The VIP Ultrasound Protocol
Wound healing rate is higher when contact ultrasound therapy is followed by noncontact ultrasound therapy on sub-acute and chronic lower extremity ulcers of various etiologies requiring selective debridement, as compared to…
- Trial name
- NCT02045303
- Testing
- Contact Ultrasound Therapy, Noncontact Ultrasound Therapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Texas Health Resources
Tranexamic Acid, Trauma
Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery
This study was done to evaluate the efficacy of Tranexamic Acid (TXA) in reducing blood transfusion requirement in patients of lower limb trauma undergoing surgery.
- Conditions
- Tranexamic Acid, Trauma, Lower Extremity Fracture
- Trial name
- NCT04986813
- Testing
- Tranexamic acid injection, Normal Saline
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Jaspreet Singh
Overuse Injury, Lower Extremity Problem
Step Rate Retraining to Reduce Injury and Disability (STRIDe)
This study will be the first project to evaluate the effectiveness of wearable technology (Garmin Forerunner35) while performing gait retraining in field on military members.
- Conditions
- Overuse Injury, Lower Extremity Problem, Stress Injury, Repetitive, Patellofemoral Pain Syndrome
- Trial name
- STRIDe (NCT04747223)
- Testing
- Run Gait Retraining
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Army-Baylor University Doctoral Program in Physical Therapy
Lower Extremity Injury
Preventing Injury in Elite Orienteerers
The aim of this study is to investigate the effect a specific exercise program on the incidence of injuries in the lower extremity. 72 elite orienteerers, aged 18-40 years, are allocated to an intervention or control group.
- Trial name
- NCT03408925
- Testing
- Exercise program
- Where
- Sweden
- Volunteers
- 66 people
- Sponsor
- Karolinska Institutet
Spinal Cord Injuries, Paraplegia
Evaluation of Safety and Performance of the Atalante System With Patients With Lower Limb Paralysis
The study is a prospective, open, bicentric and observational study. It is conducted to assess the safety and performance of the Atalante exoskeleton system with patients with lower limb paralysis.
- Conditions
- Spinal Cord Injuries, Paraplegia, Paralysis, Lower Limbs, Lower Extremity
- Trial name
- NCT04110561
- Testing
- Use of the Atalante exoskeleton
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Wandercraft
Amputation, Traumatic, Traumatic Amputation of Lower Extremity
What is the Optimal Stiffness and Height of a Running-specific Prosthesis?
The proposed study aims to characterize the effects of running-specific leg prosthetic stiffness and height during on performance during running and sprinting to optimize running-specific prosthesis prescription.
- Conditions
- Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
- Trial name
- NCT02318979
- Testing
- Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Spinal Cord Injuries, Cerebral Palsy
LEAP a New Overground Body Weight Support Robot: Usability Trial
People with central nervous system disorders such as spinal cord injury, stroke, cerebral palsy, Parkinson's disease, multiple sclerosis, etc… often have impaired lower extremity function that limits activities of daily life and…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Parkinson Disease, Multiple Sclerosis
- Trial name
- LEAP (NCT03458169)
- Testing
- Therapist LEAP session feedback, Participant LEAP session feedback, LEAP risk control validation
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Clinique Romande de Readaptation
Lower Extremity Motor Dysfunction, Spinal Cord Injury
Evaluation of the Effectiveness and Safety of AI-Robotics
Evaluation of the effectiveness and safety of the lower extremity exoskeleton rehabilitation training robot
- Trial name
- ART (NCT03452059)
- Testing
- AiLegs, AiWalker and HKAFO
- Where
- China
- Volunteers
- 40 people
- Sponsor
- AI-Robotics Technology Co., Ltd
Knee Injuries, Anterior Cruciate Ligament Injuries
Effect of Neuromuscular Warm-up on Injuries in Female Athletes
The goal of the study is to determine effect of coach-led neuromuscular warm-up on non-contact, lower extremity (LE) injury rates among female athletes in a predominantly non-white public high school system.
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries, Ankle Injuries, Lower Extremity Injuries
- Trial name
- NCT01092286
- Testing
- neuromuscular warm-up
- Where
- United States
- Volunteers
- 1,653 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Lower Extremity Weakness Distal, Distorted; Balance
Assessment and Referral Versus Exercise in Primary Prevention of Falls: PA Healthy Steps Program
Older adults at high risk of falls will complete the PA Healthy Steps program. This program will be implemented by research staff who will follow the training manual and implement the program as it was designed to assess the…
- Trial name
- NCT01552551
- Testing
- Assessment and education, Healthy Steps with Falls Case Management, Healthy Steps in Motion
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- University of Pittsburgh
Overuse Injuries, Musculoskeletal Make-up in the Lower Extremities
Knowledge of Predicting Increased Risk for an Overuse Injury in Runners
The purpose of this study is to examine the skeleton of the legs and the running style in order to predict a possible overuse injury.
- Trial name
- NCT01979562
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Lower Extremity Musculoskeletal Injury
Do Common Physical Tests Predict Injury or Performance
Field tests are convenient, simple tests that serve as estimates of components of athletic performance like power speed, and agility.
- Trial name
- TEAM (NCT01804894)
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- High Point University