Clinical trials: Lower Extremity
Movement, Abnormal, Lower Extremity Problem
Gluteal Activation Plus Movement Retraining
The purpose of this study is to determine if an isometric gluteal activation home exercise program (HEP) combined with a movement retraining program utilizing feedback cues produces significant changes in scores on the Forward…
- Trial name
- NCT07293039
- Testing
- Control HEP focusing on isometric gluteal activation, Experimental HEP focusing on isometric gluteal activation plus a movement retaining program
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Pre-frail Senior Adults
What Are the Effects of a Bilateral Hip Exoskeleton During Daily Use by 65+ Adults?
Despite the huge popularity exoskeletons have gained in the past years and the benefits that they have shown to provide to users, there are still many aspects of wearing an exoskeleton that have yet to be determined.
- Trial name
- NCT06041100
- Testing
- Exoskeleton
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures
Introduction: Approximately 35% patients can not return to sports after anterior cruciate ligament reconstruction(ACLR). Persistent quadriceps weakness is a factor that prevents patients return to sports.
- Trial name
- NCT04988828
- Testing
- Whole body vibration
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pes Planus
Plantar Fascia and Achilles Tendon Thickness and Flexibility in Pes Planus
The aim of this study is to examine the plantar fascia and Achilles tendon thickness and flexibility in individuals with pes planus.
- Trial name
- NCT06987422
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Running, Leg Injuries
Exercise Interventions, Running Biomechanics and Injury in Novice Runners
The purpose of this study is to understand the effects of muscle strengthening and balance exercise interventions on muscle strength, running mechanics and postural control in novice recreational runners.
- Trial name
- NCT01900262
- Testing
- Strengthening, Balance Training, Stretching
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Calgary
ACL - Anterior Cruciate Ligament Rupture
Bio ACL Reconstruction Amnion Collagen Matrix Wrap and Stem Cells
Collagen based -membrane derived from amniotic tissue can be used to help reestablish the natural synovial lining of the reconstructed ACL, in effect acting as both a barrier from the synovial fluid and as a scaffold to contain…
- Trial name
- BioACLRCT (NCT03294759)
- Testing
- Bio ACL, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Hamstring Contractures, Muscle Tightness
Immediate and 24-hour Effects of HyperVolt, Body Tempering, and Cupping Compared to Stretching on Hamstring Flexibility
The purpose of this study is to compare the effects of the HyperVolt percussive massage device, body tempering, and dry cupping to static stretching of the hamstrings of healthy adults aged 18-39 years on the active knee…
- Trial name
- NCT05793242
- Testing
- Hypervolt, Body Tempering, Dry cupping
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Prefrontal Hemodynamics, Muscle Strength
Lower Limb Strength and Power as Predictors of Brain Blood Flow During Exercise
This study aims to investigate the predictive value of lower limb muscle strength and explosive power on exercise-induced prefrontal hemodynamic responses.
- Conditions
- Prefrontal Hemodynamics, Muscle Strength, Physical Performance
- Trial name
- LLSPP (NCT07575802)
- Testing
- Standardized Lower-Limb Physical Performance Assessment and Aerobic Exercise Task
- Where
- Russia
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Trained Athletes, Untrained
Trained vs. Untrained: Lower Extremity Pressure Changes
Research shows that how well oxygen moves from the lungs into the blood (called lung diffusing capacity) is linked to a person's aerobic fitness and endurance training.
- Trial name
- TULiP (NCT07897357)
- Testing
- Lower body positive and negative pressure
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Total Knee Arthroplasty
Comparison Between Brainlab Knee 3 Computer-assisted Navigation Systems and Conventional Instruments in TKA: a Prospective Cohort Study.
This is a a prospective cohort study. According to the inclusion criteria, volunteers were recruited from patients undergoing total knee arthroplasty.
- Trial name
- NCT04960345
- Testing
- Brainlab Knee 3
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Healthy
Young Age Soccer Player's Lower Limb Muscle Imbalance and Functional Status
A randomized controlled trial is designed to examine the effects of low-load and high-velocity eccentric exercises on lower limb muscular properties, imbalances and functional status of 13-15 years old female football players.
- Trial name
- NCT06053632
- Testing
- Low-load and high-velocity - lying prone - eccentric hamstring exercise
- Where
- Lithuania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healty Volunteers, Sedantary
The Role of Lower Limb Neural Mobilization in Improving Balance and Performance
Neural mobilization (NM) is a technique used to enhance the mobility of peripheral nerves relative to surrounding tissues, aiming to reduce physiological tension and improve movement quality.
- Conditions
- Healty Volunteers, Sedantary, Young, Female
- Trial name
- NCT06951048
- Testing
- Group I (Neural Mobilization), Group II (Neural Mobilization + Dynamic Stretching), Group III (Dynamic Stretching Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University
Restless Leg Syndrome
Effects of Static Stretching and Strength Training on Antenatal Restless Leg Syndrome
Restless Legs Syndrome (RLS) is a prevalent sensorimotor disorder affecting pregnant women, particularly in the third trimester, and is associated with sleep disturbances, fatigue and reduced quality of life.
- Trial name
- NCT07642089
- Testing
- Static Stretching, Static Stretching + Strength Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Young People
The Effect of Use of Medical Masks on Exercise Capacity and Leg Endurance in Youth
The use of masks has become an important part of life in outbreak conditions. In order to prevent the spread of the outbreak, many people in society may have to wear masks for hours during the day.
- Trial name
- NCT04785378
- Testing
- Medical mask, Field tests
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Diabetic Foot, Ulcer Foot
Bioactive Split Thickness Skin Allograft Versus Standard of Care in the Treatment of Diabetic Foot Ulcers
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data as well as assess performance and safety of a commercially available human split thickness skin allograft with SOC…
- Trial name
- NCT04040426
- Testing
- Human split thickness skin allograft, Additional Outer Dressing Applicaiton, Offloading
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Professional Education and Research Institute
Flat Foot [Pes Planus] (Acquired), Left Foot, Flat Foot [Pes Planus] (Acquired), Right Foot
Flat Foot and Coronal Spinopelvic Alignment
This study aimed to present the influence of unilateral and bilateral flat foot on coronal spinopelvic alignment in asymptomatic young healthy males.
- Conditions
- Flat Foot [Pes Planus] (Acquired), Left Foot, Flat Foot [Pes Planus] (Acquired), Right Foot, Flat Foot Acquired Bilateral (Pes Planus), Pelvic Obliquity
- Trial name
- NCT04746508
- Where
- Turkey (Türkiye)
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ligament; Laxity, Recurrent Patellar Dislocation
Clinical Significance and Coexistence of Polymorphisms of Individual Collagen-coding Genes
The purpose of this study is to assess correlation between recurrent patella dislocation and genetic polymorphism rs1800012 of the COL1A1 Gene and rs12722 of the COL5A1 Gene.
- Trial name
- NCT05763108
- Testing
- genetic test, Beighton joint laxity test
- Where
- 2 sites in Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Rest Cramps
Exploring the Role of Magnesium in Rest Cramps
This study sets out to show whether infusions of magnesium can lessen the frequency of rest cramps and to determine whether rest cramp sufferers have a deficiency in magnesium.
- Trial name
- NCT00423540
- Testing
- Intravenous Infusion of Magnesium Sulfate
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Subjects, Restless Legs Syndrome
Infra-slow Oscillations During Sleep
In this study the investigators plan to systematically characterise infra-slow EEG oscillations during sleep, explore their relationship to the microstructure of sleep, and investigate its role in the physiology and…
- Conditions
- Healthy Subjects, Restless Legs Syndrome, Periodic Limb Movements During Sleep
- Trial name
- SleepD-ISO (NCT02532608)
- Testing
- Acute sleep deprivation
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Stephany Fulda
Stroke, Hemiparesis
Sideways Treadmill Training to Improve Paretic Leg Stepping in Persons Post-Stroke
People who are living in the community following a stroke fall frequently. The ability to take a step in response to a balance disturbance helps to prevent falls but stroke survivors tend not to step with their paretic leg in…
- Trial name
- NCT02516176
- Testing
- treadmill training
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
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