Clinical trials: Low Level Laser
Lymphedema
Low Level Laser Treatment and Breast Cancer Related Lymphedema
Manual Lymphatic Drainage (massage therapy) with compression (wearing a tight sleeve on the arm) is the current standard of treatment for breast cancer related lymphedema (arm swelling).
- Trial name
- NCT00852930
- Testing
- laser and MLD combined, laser alone, manual lymphatic drainage
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vanderbilt University
Palatal Wound
Comparison of Two Different Low-level Laser Intensity Protocols on the Healing of Palatal Wounds
The aim of this study was to compare two intensities of LLLT on wound healing process of the donor palatine area after CTG removal.
- Trial name
- NCT02580357
- Testing
- Low Level Laser Therapy, GaAlAs laser
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Obstructive Sleep Apnea
Dextrose Prolotherapy Versus LLLT in Treatment of Obstructive Sleep Apnea
This study was conducted on 26 patients with obstructive sleep apnea. The patients were divided randomly and equally into two equal groups.
- Trial name
- NCT06427161
- Testing
- LLLT application, dextrose injection
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Mansoura University
Sleep Bruxism
Evaluation of Muscle Activity, Bite Force and Salivary Cortisol in Children With Bruxism
Bruxism is a repetitive activity of the masticatory muscles characterized by grinding and/or clenching one's teeth or parafunctional movements of the mandible.
- Trial name
- Bruxism (NCT02757261)
- Testing
- Laser, Occlusal splint
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pain, Low Back Pain
Low Level Laser Therapy in the Dorsal Root Ganglion in the Treatment of Chronic Low Back Pain
Chronic axial low back pain is a public health problem and has a high socioeconomic impact. The dorsal ganglion of the second spinal nerve (GDL2) is a cluster of neuronal bodies responsible for sensory afferent inputs from more…
- Conditions
- Pain, Low Back Pain, Nociceptive Pain, Neuropathic Pain
- Trial name
- NCT02529670
- Testing
- Laser, Drug: Lidocaine, Radiofrequency
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Nove de Julho
Diabetic Foot Ulcer
Low Level Laser Therapy and Expression of VEGF, NO, VEGFR-2, HIF-1α in Diabetic Foot Ulcers
The purpose of this study is to examine the changes of factors including Vascular Endothelial Growth Factor(VEGF), VEGFReceptor-2, Nitric Oxide and hypoxia-inducible factor-1α (HIF-1α), measurements of oxygen saturation in…
- Trial name
- NCT02452086
- Testing
- Low Level Laser(Ga-As)
- Where
- Iran
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Tarbiat Modarres University
Burns
Response of Aerobic Capacity to Low Level Laser Therapy in Burned Patients
Severe burns can decrease pulmonary function and impair aerobic capacity persisting for long times post injury. Low level laser therapy is a new modality used to improve aerobic capacity, enhance exercise performance, increase…
- Trial name
- NCT04755296
- Testing
- Low level laser therapy, Aerobic exercises, Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Osgood-Schlatter Disease, Sever's Disease
Low-Level Laser Therapy for Osgood-Schlatter or Sever Pain in Youth Athletes
The goal of this clinical trial is to learn if low-level laser therapy (also called photobiomodulation) works to treat knee or heel pain in physically active children and adolescents with Osgood-Schlatter disease or Sever…
- Trial name
- NCT07446517
- Testing
- Photobiomodulation (Low-Level Laser Therapy)
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- Medical University of Gdansk
Hearing Loss
The Effect of Low-Level Laser Stimulation on Hearing Thresholds
The purpose of this study is to determine whether low-level laser therapy can improve hearing thresholds in individuals with hearing loss. Subjects will be randomly assigned to a treatment, placebo, or control group.
- Trial name
- NCT01820416
- Testing
- Low-level Laser Therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Iowa
Dental Malocclusion
Evaluation of the Effect of Corticotomy and Low Level Laser Therapy on Orthodontic Tooth Movement
The aim of the present study was to compare, a standard efficient technique in accelerating OTM as surgical corticotomy as a gold standard versus surgical corticotomy combined with LLLT in an attempt for further acceleration of…
- Trial name
- NCT03906084
- Testing
- Corticotomy and low laser therapy, Corticotomy facilitated Orthodontics
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lateral Ankle Sprain, Ankle Sprain 1St Degree
Therapeutic Low Laser Therapy and Kinesio Taping for Lateral Ankle Sprain
HYPOTHESIS Null Hypothesis (H0): There is no significant effect of therapeutic low laser therapy and kinesio taping in patients with grade 1 \& 2 lateral ankle sprain.
- Conditions
- Lateral Ankle Sprain, Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
- Trial name
- NCT07235943
- Testing
- Using Low-Level Laser Therapy, Combined: Low Laser Therapy with Kinesio Taping
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- University of Lahore
Gastric Cancer, Gastric High-grade Intraepithelial Neoplasia
Establishment and Effectiveness Evaluation of a Training System for Confocal Laser Endomicroscopy
Gastrointestinal endoscopy is a vital method for screening and diagnosing gastric cancer. It aids in identifying the tumor's location within the stomach and its macroscopic type, and allows biopsy for histological confirmation.
- Conditions
- Gastric Cancer, Gastric High-grade Intraepithelial Neoplasia, Gastric Low-grade Intraepithelial Neoplasia, Gastritis
- Trial name
- NCT06981819
- Testing
- Probe-based Confocal Laser Endomicroscopy by Experts, magnifying endoscopy with blue laser imaging, Probe-based Confocal Laser Endomicroscopy by trainees
- Where
- China
- Volunteers
- 147 people
- Sponsor
- Changhai Hospital
Myofacial Pain Syndrome
The Effect of Low Level Laser Therapy (LLLT) in Myofacial Pain Syndrome
Temporomandibular disorders (TMDs) are the major cause of non-dental pain in orofacial area. Laser therapy can be considered as one of the most recent treatment approaches in the field of physiotherapy.
- Trial name
- NCT01417637
- Testing
- Low level laser therapy
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Dentin Hypersensitivity
Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity
Dentin hypersensitivity (DH) is a common clinical problem frequently seen in dental patients. According to Splieth et al., the prevalence of dentin hypersensitivity is 3-98% in adult population.DH is described as a short, sharp…
- Trial name
- NCT05927831
- Testing
- Grape Seed Extract, Low-level laser therapy
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Manipal University College Malaysia
Psoriasis Vulgaris
Low-Salt Diet Effect on Th17-Mediated Inflammation and Vascular Reactivity in Psoriasis
Psoriasis presents an independent cardiovascular risk factor characterized by chronic low-grade systemic inflammation and oxidative stress which altogether might lead to endothelial dysfunction.
- Trial name
- NCT05892640
- Testing
- Low-Salt Diet
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Plantar Fascitis, Achilles Tendon Pain
Effect of HILT vs LLLT in Treatment of Patients With Achilles Tendinitis or Plantar Fasciitis
The aim of this study is to evaluate and compare the changes of heel pain, functional health and well-being after high-intensity and low-level laser therapy for plantar fasciitis or Achilles tendinopathy
- Trial name
- NCT03873961
- Testing
- High-intensity laser therapy, Low-level Laser therapy
- Where
- Lithuania
- Volunteers
- 155 people
- Sponsor
- Lithuanian University of Health Sciences
Primary Dysmenorrhea
Low Versus High Intensity Laser Therapy on Primary Dysmenorrhea
Primary dysmenorrhea constitutes a significant health, social and economic problems. It involves a broad spectrum of both physical and emotional manifestations with a prevalence that can reach 50 up to 91 % in young women .
- Trial name
- NCT05448027
- Testing
- Low intensity laser therapy, High intensity laser therapy
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Cord Injuries
Evaluation of Sensory-motor Response to Low-level Laser Therapy for the Treatment of Spinal Injuries
Spinal cord injuries have become increasingly frequent due mainly to the increase in urban violence. The growing number of automobile collisions and violence-related events merits particular attention, as such occurrences can…
- Trial name
- NCT03031223
- Testing
- low-level laser therapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Temporomandibular Disorders (TMD), Temporomandibular Joint Disorder
A Retrospective Randomized Controlled Study Comparing the Effectiveness of Low-level Laser Therapy and Ultrasound Therapy in Reducing Pain and Increasing Maximum Mouth Opening in Forty-six Patients With Temporomandibular Disorders
Temporomandibular disorders (TMDs) are the most common cause of non-dental orofacial pain, involving the temporomandibular joint (TMJ), masticatory muscles, or associated structures.
- Trial name
- NCT07378462
- Testing
- Low-Level Laser Therapy, Ultrasound therapy
- Where
- Nepal
- Volunteers
- 46 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Breast Cancer
Laser Therapy for the Prevention of Radiodermatitis in Breast Cancer Patients
Up to 90% of the radiotherapy patients will develop a certain degree of skin reaction at the treated area, also known as radiodermatitis (RD).
- Trial name
- TRANSDERMIS (NCT02443493)
- Testing
- Low-level laser, radiotherapy
- Where
- Belgium
- Volunteers
- 139 people
- Sponsor
- Hasselt University