Clinical trials: Low Blood Pressure
Fluid Overload and Hypertension in Hemodialysis Patients
Effect of Sodium Concentration of Priming and Rinsing Fluids on Weight Gain
Sodium loading during hemodialysis treatment is common and may contribute to increased interdialytic weight gain and hypertension.
- Trial name
- NCT01168947
- Testing
- 5% dextrose solution
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Renal Research Institute
Kidney Transplant, Delayed Graft Function
Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation
Prospective double blind randomized controlled trial. By randomizing patients undergoing kidney transplantation into a conventional catecholamine drug (dobutamine) blood pressure maintenance group and a terlipressin-complexed…
- Conditions
- Kidney Transplant, Delayed Graft Function, Intraoperative Hypotension
- Trial name
- NCT06855758
- Testing
- terlipressin
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Friendship Hospital
Cesarean Section Complications, Hypotension
Noninvasive Continuous Blood Pressure Monitoring for Cesarean Delivery
Noninvasive continuous blood pressure monitoring for preventing post-spinal hypotension during cesarean delivery: A randomized controlled trial
- Trial name
- NCT04752904
- Testing
- ClearSight System
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital
Chronic Kidney Disease, Hypertension
Aerobic Training and Arterial Stiffness in Chronic Kidney Disease (CKD) Patients
The current study is designed to examine the impact of 16 weeks of moderate intensity aerobic training on arterial stiffness and blood pressure in stage 3 chronic kidney disease (CKD) patients.
- Conditions
- Chronic Kidney Disease, Hypertension, Diabetes
- Trial name
- NCT01399489
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Springfield College
Hypotension, Hip Fractures
Heart and Renal Failure in Hip Fracture Surgery
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension.
- Conditions
- Hypotension, Hip Fractures, Renal Insufficiency, Heart Injuries
- Trial name
- NCT03532919
- Testing
- Serum Tropinin
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Sahlgrenska University Hospital
Hypotension
Haemodynamic Response to General Anaesthesia in Healthy Orthopaedic Patients
Continuous cardiovascular monitoring as part of management of high-risk surgical patients is widely practiced, however its role in low-risk surgical patients is unclear.
- Trial name
- HRespToAS (NCT02834000)
- Testing
- LiDCO rapid™ CNAP monitoring
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Intraoperative Hypotension
Intraoperative Implementation of the Hypotension Probability Indicator
Reducing intraoperative hypotension using FlotracIQ with HPI software.
- Trial name
- HYPE (NCT03376347)
- Testing
- FlotracIQ with HPI algorithm
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obese Individuals, Central Adiposity
Post-exercise Blood Pressure With Inorganic Nitrate
This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise…
- Trial name
- BEET-DOWN (NCT07869472)
- Testing
- Beetroot Juice - Active + Exercise, Beetroot Juice - Active + No exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia
High Myopia, Low Intraocular Pressure
Improved Operation of Low Intraocular Pressure in Phacoemulsification for Patients With High Myopia Complicated With Cataract
Approximately 60 participants at Eye Hospital of Wenzhou Medical University during October,2021 to January 2022 will be enroll in the investigators' study.
- Trial name
- NCT05201677
- Testing
- Supplement of perfusion fluid through the subiris suspensory ligament space from the lateral incision
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yune Zhao
Hypotension During Surgery
The Hypotension Prediction Index in Major Abdominal Surgery
The goal of this randomized clinical trial is to compare different types of advanced hemodynamic monitoring in patients undergoing major abdominal surgery.
- Trial name
- NCT06247384
- Testing
- Hypotension Prediction Index Hemodynamic Monitoring
- Where
- Poland
- Volunteers
- 226 people
- Sponsor
- Jakub Szrama
Intraoperative Hypotension, Acute Kidney Injury
Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension
In order to reduce the incidence of IOH, various goal-directed therapy (GDT) protocols have already been introduced with success regarding the reduction of postoperative AKI and MINS.
- Conditions
- Intraoperative Hypotension, Acute Kidney Injury, Myocardial Injury After Non-cardiac Surgery
- Trial name
- Clearsight (NCT06291714)
- Testing
- GDT-based hemodynamic management based on Clearsight device
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University of Giessen
Intraoperative Hypotension, Spinal Aneshtesia
Dural Sac Area-Guided Spinal Anesthesia Dosing for TURP
This randomized controlled study will evaluate whether individualizing the dose of spinal anesthesia according to the ultrasound-derived dural sac cross-sectional area (DSCSA) can improve hemodynamic stability in patients…
- Conditions
- Intraoperative Hypotension, Spinal Aneshtesia, TURP(Transurethral Resection of Prostate)
- Trial name
- NCT07794852
- Testing
- DSCSA-Guided Individualized Spinal Anesthesia Dosing, Bupivacaine, Fentanyl (FEN)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Symptomatic Neurogenic Orthostatic Hypotension (NOH), Parkinson's Disease
Fipamezole in Neurogenic Orthostatic Hypotension
The purpose of this study is to determine whether Fipamezole is effective in the treatment of orthostatic hypotension and related symptoms in multiple system atrophy and Parkinson's disease.
- Conditions
- Symptomatic Neurogenic Orthostatic Hypotension (NOH), Parkinson's Disease, Multiple System Atrophy
- Trial name
- Foehn (NCT00758849)
- Testing
- Fipamezole
- Where
- 4 sites in France, Portugal
- Volunteers
- 24 people
- Sponsor
- Juvantia Pharma Ltd
Symptomatic Orthostatic Hypotension
Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension
To study the effect of midodrine against the symptoms of orthostatic hypotension
- Trial name
- NCT01515865
- Testing
- Midodrine HCl
- Where
- 32 sites in United States, Czechia and 2 more
- Volunteers
- 98 people
- Sponsor
- Shire
Heart Failure, Vasoplegia
Prevention of Low Blood Pressure After Cardiac Surgery in Heart Failure Patients With a Filter Called CytoSorb.
Vasoplegia is a common complication after heart surgery for heart failure. With vasoplegia, the blood vessels can no longer squeeze properly, causing low blood pressure that is sometimes difficult to treat with medication.
- Trial name
- CytoSorb-HF (NCT04812717)
- Testing
- CytoSorb device
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Leiden University Medical Center
Anesthesia Induced Hypotension, Hypotension Drug-Induced
Comparison of Pleth Variability Index vs. Diastolic Shock Index for Predicting Hypotension During Anesthesia Induction
This study aims to explore the frequent occurrence of hypotension during anesthesia induction due to anesthetic drugs or fasting. Predicting this condition is important for patient safety and anesthesia management.
- Trial name
- NCT06589674
- Testing
- Pulse variability index measurement, Diastolic shock index
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Kocaeli City Hospital
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia.
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556370
- Testing
- Normal saline, Norepinephrine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- General Hospital of Ningxia Medical University
Disorder of Shoulder, Anesthesia
Effect of Phenylephrine During Shoulder Arthroscopic Surgery
The purpose of this study is to determine whether phenylephrine infusion are effective in the prevention of hypotension after changing position to beach chair position during general anesthesia for shoulder arthroscopic surgery.
- Trial name
- NCT02585570
- Testing
- Phenylephrine
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Inje University
Radiography, Interventional
Cerebral Perfusion During Induction of General Anesthesia
Arterial hypotension during general anesthesia remains a factor of poor outcomes, increases the risk of myocardial infarction, acute kidney injury and 1-year mortality.
- Trial name
- NCT03769142
- Testing
- All monitoring
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia
Tachycardia as an Indication for Prophylactic Phenylephrine Injection in Caesarean Section Under Spinal Anesthesia; an Observational Study
The value of phenylephrine administration in response to tachycardia in preventing hypotension after spinal anesthesia in elective cesarean section.
- Trial name
- NCT06220942
- Testing
- Phenylephrine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
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