Clinical trials: Low Back Pain, pill or tablet or capsule or oral, open to volunteers
- Condition Low Back Pain
- Drug or intervention pill OR tablet OR capsule OR oral
- Status Open to volunteers
Chronic Low-back Pain, Back Disorder
Movement Performance in Persons With Chronic Back Pain
The goal of this laboratory-based cross-over randomized controlled study is to study the immediate effects Spinal manipulative therapy (SMT) and exercise therapy (ET) compared to open-label placebo (OLP) on movement performance…
- Trial name
- NCT06891625
- Testing
- SMT, ET, OLP
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Non-specific Chronic Low Back Pain
Effects of Dead Bug Exercises With and Without Diaphragmatic Breathing in Patients With Chronic Non-specific Low Back Pain.
This study outlines a Randomized Clinical Trial (RCT) evaluating whether combining diaphragmatic breathing with Dead Bug exercises provides superior benefits compared to Dead Bug exercises alone for individuals suffering from…
- Trial name
- NCT07905222
- Testing
- Dead Bug Exercises with Diaphragmatic Breathing, Dead Bug Exercises Only
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Management and Technology Lahore
Radiculopathy, Lumbosacral Region, Back Pain With Radiation
Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.
This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back pain (LBP) and followed by…
- Conditions
- Radiculopathy, Lumbosacral Region, Back Pain With Radiation, Low Back Pain
- Trial name
- NCT05721027
- Testing
- Ibuprofen 400 mg, Dexamethasone Oral, Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Chronic Lower Back Pain (CLBP)
Mechanistic Evaluation of Polypharmacy Effects for Pain
This is a single-group, within-subject, double-blind, double-dummy, placebo-controlled study evaluating whether gabapentin (Neurontin) changes the analgesic, safety, and subjective effects of the opioid hydromorphone (Dilaudid)…
- Trial name
- PAT (NCT07846020)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Maryland, Baltimore
Chronic Low-back Pain
Palmitoylethanolamide Modulates Central Sensitisation and Neuroinflammation in Chronic Low Back Pain
Low back pain (LBP) is a public and occupational health problem that is a major professional, economic and social burden. Up to 84% of the general population will experience an episode of LBP during its life time, and recurrence…
- Trial name
- NCT07772141
- Testing
- Palmitoylethanolamide
- Where
- Egypt
- Volunteers
- 106 people
- Sponsor
- Beni-Suef University
Chronic Low Back Pain (Non-specific, Uncomplicated)
Auricular Acupressure for Chronic Low Back Pain in Postmenopausal Women
Participants were recruited from two areas in southern Taiwan: the traditional Chinese medicine outpatient clinics at Kaohsiung Medical University Chung-Ho Memorial Hospital and Kaohsiung Municipal Siaogang Hospital, as well as…
- Trial name
- AA for CLBP (NCT07829289)
- Testing
- auricular acupressure
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Chia Fen Wu
Low Back Pain, Kinesiophobia (Fear of Movement)
Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain
Brief Summary The goal of this clinical trial is to learn if MUSIC CARE©, a music-based therapy tool, can improve the physical abilities of people with chronic low back pain (back pain that lasts more than 3 months).
- Conditions
- Low Back Pain, Kinesiophobia (Fear of Movement), Chronic Low-back Pain (cLBP)
- Trial name
- LOMBALZIC' (NCT07731204)
- Testing
- Receptive Music Therapy
- Where
- France
- Volunteers
- 34 people
- Sponsor
- LNA SANTE
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Chronic Low Back Pain (CLBP), Insomnia
Resilience Enhancement Following Sleep Treatment
The primary objective of this study is to evaluate the efficacy of an adaptive intervention targeting both insomnia and positive affect in improving pain outcomes for adults with chronic low back pain (cLBP) and comorbid…
- Trial name
- REST (NCT07298941)
- Testing
- Cognitive-behavioral therapy for insomnia (CBTi), CBTi + Savoring Meditation, CBTi + Pain Education
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Virginia
Chronic Lower Back Pain
Assessment of Usability and Satisfaction With a Take-home Device Presenting Sound and Body Stimulation for Back Pain
Pain symptoms can have a variety of ways to be treated, from medications to physical therapy, with several options being available to patients.
- Trial name
- NCT06619418
- Testing
- TENS device, Integrative health modalities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Non-specific Low Back Pain
Toludesvenlafaxine for Non-specific Low Back Pain
Chronic non-specific low back pain is the leading cause of productivity loss and disability worldwide, constituting a major public health challenge.
- Trial name
- NCT07709416
- Testing
- Active Comparator #1, Toludesvenlafaxine
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Beijing Tiantan Hospital
Osteoarthritis, Knee, Diabetic Neuropathic Pain
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs).
- Conditions
- Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
- Trial name
- CPMP (NCT05986292)
- Testing
- LY3016859 ISA, LY3556050 ISA, LY3526318 ISA
- Where
- 64 sites in United States, Puerto Rico
- Volunteers
- 10,000 people
- Sponsor
- Eli Lilly and Company
Back Pain, Low
Duloxetine for LBP
This research study will help determine whether a medication called duloxetine can improve back pain. It is well documented that many participants who come to the ER with acute low back pain still have low back pain 3 months…
- Trial name
- NCT05851976
- Testing
- Naproxen, Duloxetine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Montefiore Medical Center
Low Back Pain, Chronic Pain
Dronabinol as an Adjunct for Reducing Pain
This exploratory, proof-of-concept study is a double-blind (participants and investigators will be blinded), placebo-controlled, randomized, two-arm clinical trial of Marinol [dronabinol, synthetic Δ9-tetrahydrocannabinol (THC)]…
- Conditions
- Low Back Pain, Chronic Pain, Back Injuries
- Trial name
- DARP (NCT06454669)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Christopher D. Verrico
Non-specific Low Back Pain, Pain Management
Venlafaxine for Non-specific Low Back Pain
Chronic non-specific low back pain is the leading cause of productivity loss and disability worldwide, constituting a major public health challenge.
- Trial name
- NCT07737158
- Testing
- Control Group, Venlafaxine group
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Beijing Tiantan Hospital
Low Back Pain, Myofascial Pain Syndrome Lower Back
Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial
Rationale: Low back pain (LBP), or myofascial pain syndrome (MPS) of the low back, accounts for approximately 2.63 million visits in the United States, or 2.3 percent of annual Emergency Department (ED) visits.
- Trial name
- T-PIMPS (NCT04704297)
- Testing
- Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below., Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below., Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Low Back Pain
Evaluation of a Program to Prevent Recurrences of Episodes of Acute Low Back Pain, Assisted by the Axomove Application
The purpose of this study is to demonstrate that the prescription of specific exercises, supervised by a numerical application, reduces the rate of recurrence of episodes of acute low back pain
- Trial name
- NA-PLU-MALODOS (NCT07915128)
- Testing
- 2 exercises program supervised by a physical therapist via a digital application, Care as usual
- Volunteers
- 194 people
- Sponsor
- University Hospital, Bordeaux
Lumbosacral Radiculopathy
Safety and Efficacy Study on AFA-281 for the Treatment of Low Back Pain
The goal of this clinical trial is to evaluate if the drug candidate AFA-281 works to treat chronic low back and leg pain caused by painful lumbosacral radiculopathy (PLSR) in adults.
- Trial name
- NCT06649747
- Testing
- AFA-281
- Volunteers
- 408 people
- Sponsor
- Afasci Inc
Low Back Pain (LBP)
Pilot Study: Clinical Trial of Ultrasound Guiding Pharmacopuncture Therapy for Acute Low Back Pain
This pilot randomized controlled clinical trial aims to evaluate the effectiveness and safety of ultrasound-guided deep pharmacopuncture therapy for acute low back pain (LBP) that occurs within seven days following a traffic…
- Trial name
- NCT07126951
- Testing
- Ultrasound-guided Deep Pharmacopuncture Treatment, Korean medical treatment
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Chronic Pain, Low Back Pain
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain
The main purpose of this study is to test the safety and efficacy of study drug for the treatment of chronic low back pain (CLBP).
- Trial name
- BP07 (NCT07641504)
- Testing
- LY4065967
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company