Clinical trials: Low Back Disorder
Chronic Low Back Pain, Degenerative Disc Disease
Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain
Intervertebral disc pathology accounts for 40% or more cases of chronic LBP. Available treatment options do not improve the underlying degenerative condition hence This indicates the need for new therapies.
- Trial name
- NCT04849429
- Testing
- Platelet rich plasma (PRP) with exosomes, Normal Saline
- Where
- 2 sites in India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Himanshu Bansal Foundation
Knowledge, Attitudes, Practice, Low Back Pain
Effect of an E-learning Intervention on Knowledge, Attitudes and Beliefs of Healthcare Professionals Managing Low Back Pain.
The purpose of the current research project is to examine if the healthcare professionals (HCPs) knowledge, attitudes, beliefs and behavior about the management of low back pain (LBP) patients changes following an e-learning…
- Conditions
- Knowledge, Attitudes, Practice, Low Back Pain, Physical Therapy, Physicians
- Trial name
- NCT05284669
- Testing
- Experimental e-learning, Traditional e-learning
- Where
- Belgium
- Volunteers
- 2,720 people, healthy volunteers welcome
- Sponsor
- Antoine Fourré
Low Back Pain, Kinesiophobia (Fear of Movement)
Feasibility of an Augmented Reality Novel Approach for the Rehabilitation of Chronic Low Back Pain Patients With Kinesiophobia
The goal of this clinical trial is to evaluate the feasibility, safety, and initial effectiveness of a new augmented reality (AR) system in adults over 18 years old suffering from chronic low back pain and kinesiophobia (fear of…
- Conditions
- Low Back Pain, Kinesiophobia (Fear of Movement), Healty Volunteers
- Trial name
- NCT07527845
- Testing
- Augmented Reality (AR) Rehabilitation System
- Where
- Chile
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Pregnancy Complications, Low Back Pain
An Intervention Program for the Trunk Neuromuscular Pattern and Postural Control in Pregnant With Low Back Pain
The relevance of this study is given by the feasibility to assess the effect of an intervention program based on the functionality and trunk neuromuscular activity and postural control in pregnant women with low back pain.
- Trial name
- NCT02933086
- Testing
- Specific exercises for lumbar stabilization, Conventional therapy
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Low Back Pain
The Effect of Manipulations of the Lumbar Spine on Six Different Outcome Measures
1. Evaluation of the effect of a chiropractic adjustment (Manually Assisted Mechanical Force)on 2. surface Static EMG 3. Paraspinal cutaneous temperature 4. Range of Motion 5. Dynamic EMG 6.
- Trial name
- NCT00739570
- Testing
- AAI signature IV AMCT
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Low Back Pain, Low Back Pain, Mechanical
Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.
This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, Disc Degeneration, Disc Prolapse
- Trial name
- NCT05059249
- Testing
- Hot Pack, Manual Traction, Mechanical Traction
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Lower Back Pain
Effect of Dynamic Sitting on Pain Development
Worksite based prolonged static sitting postures can cause musculoskeletal pain. While the development of pain increases due to the constant growth of digitalization at work, numerous interventions to reduce prolonged sitting…
- Trial name
- DynSit-Pain (NCT05664776)
- Testing
- Dynamic office chair
- Where
- Austria
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences for Health Professions Upper Austria
Chronic Pain, Low Back Pain
Embodiment in Virtual Reality as a Telemedicine Digital Therapeutic for the Treatment of Chronic Shoulder Pain
Chronic shoulder pain is a common musculoskeletal pain condition that can have a profound impact on a sufferer's life and a large socioeconomic healthcare burden to society.
- Conditions
- Chronic Pain, Low Back Pain, Shoulder Pain
- Trial name
- NCT05375500
- Testing
- telemedicine digital therapeutic
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Low Back Pain, Muscle Weakness
NASM OPT for Gluteal Enhancement in Non-Athletic Women: An RCT
This RCT evaluates a 12-week NASM OPT program targeting gluteal muscle strength, hip aesthetics (shape, lift, circumference), and low back pain in 120 non-athletic women.
- Conditions
- Low Back Pain, Muscle Weakness, Body Image Disturbance
- Trial name
- GlutealEnhan (NCT06977958)
- Testing
- NASM OPT Group, General Exercise Group
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Sciatica, Low Back Pain
Effect of Muscle Energy Techniques on Functional Abilities in Patients With Discogenic Unilateral Sciatica
The purpose of the study to investigate the effect of muscle energy techniques on functional abilities of patients with chronic discogenic unilateral sciatica and to explain it from a physiological and functional point of view
- Trial name
- NCT04918238
- Testing
- Conventional program, Muscle energy technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Horus University
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Hallux Limitus, Movement, Abnormal
Foot Posture Index, Hallux Limitus in Patients With Chronic Low Back Pain. Gait With Optogait Sensor
Foot disorders have been recognized as being linked to chronic low back pain
- Conditions
- Hallux Limitus, Movement, Abnormal, Back Pain Lower Back Chronic
- Trial name
- NCT04607863
- Testing
- Case control
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Seville
Back Pain, Back Pain Lower Back
Use of Ultrasound Imaging in Confirming Osteopathic Spinal Diagnosis
In the field of Osteopathic Medicine, diagnosis of potential areas of dysfunction are diagnosed by the physician using their hands and expertise in noticing subtle differences in symmetry, tone, swelling etc..
- Conditions
- Back Pain, Back Pain Lower Back, Back Pain Lower Back Chronic, Back Pain With Radiation
- Trial name
- NCT07858071
- Testing
- Spinal Ultrasound
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Opioid Dependence, Low Back Pain
Return to Work - Will Brief Intervention Reduce Opioid-induced Back Pain?
Background Back pain is among the most common cause for sick leave in the working population and is the main cause of years lived with disability globally.
- Conditions
- Opioid Dependence, Low Back Pain, Opioid Use
- Trial name
- NCT05437861
- Testing
- Brief Intervention
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Low Back Pain, Urinary Incontinence
Investigation of the Effects of Stabilization Exercises and Pelvic Floor Muscle Training on Pain and Urinary Parameters in Individuals With Chronic Low Back Pain With Urinary Incontinence
The research will be done with people with urinary incontinence and low back pain. 3 groups of volunteer participants will be formed. The groups were planned as study group, classical application group and control group.
- Trial name
- NCT05666427
- Testing
- Pelvic floor muscle training combined with stabilization exercises, Pelvic floor muscle training
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Low Back Pain, Physical Inactivity
The Association Between Urinary Incontinence, Physical Performance, Physical Activity Levels in Women With Low Back Pain
The study is searching for the correlation between low back pain(LBP), physical performance, urinary incontinence and physical activity levels in women.
- Conditions
- Low Back Pain, Physical Inactivity, Urinary Incontinence
- Trial name
- NCT05339516
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Pinar Yasar
Low Back Pain, Musculoskeletal Pain
Soft Active Back Exosuit to Reduce Workplace Back Pain
The goal of this clinical trial is to determine if a wearable back exosuit can make it safer and easier for workers who bend, lift, and lower objects in an industrial setting.
- Conditions
- Low Back Pain, Musculoskeletal Pain, Low Back Injury
- Trial name
- NCT05802914
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wyss Institute at Harvard University
Back Pain, Back Pain, Low
Aromatherapy Randomization of Pain Management in Adults
Pain control for acute isolated back pain and sciatica is a nebulous and often illusive task in the emergency department, and a challenge face everyday by emergency medicine physicians.
- Conditions
- Back Pain, Back Pain, Low, Sciatica
- Trial name
- AROMA (NCT03377088)
- Testing
- Rose oil, Almond Oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University