Clinical trials: Long Term
Long Term Care Homes, Malnutrition Elderly
CHOICE+ Quality Improvement for Long Term Care Homes
CHOICE+ is an eLearning program that empowers staff to improve the mealtime experience of long-term care (LTC) residents. This program is based on principles that align with relationship-centered care and promote resident quality…
- Conditions
- Long Term Care Homes, Malnutrition Elderly, Malnutrition Risk in Elder
- Trial name
- CHOICE+ (NCT07505407)
- Testing
- CHOICE+ virtual training program
- Where
- 4 sites in Canada
- Volunteers
- 800 people
- Sponsor
- University of Waterloo
Adolescence Idiopathic Scoliosis
Functional Limitations, Body Structure and Function Impairments, and Quality of Life in Adults After Surgical Treatment of Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity, and a subset of patients undergo surgical correction during adolescence, most commonly posterior spinal fusion (PSF).
- Trial name
- AIS (NCT07559539)
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Józef Piłsudski University of Physical Education
Delayed Tracheostoma Healing Following Decannulation in Long-term Tracheostomy Patients
Predictive Model for Stoma Healing After Tracheostomy Decannulation in Patients With Prolonged Tracheostomy
Prolonged tracheostomy is prone to induce chronic airway mucosal injury and tracheal cartilage degeneration, which not only elevates the risks of post-decannulation complications such as persistent fistula non-healing, airway…
- Trial name
- STOMA-PRED (NCT07747844)
- Testing
- No intervention
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Capital Medical University
Psychological Well Being, Healthy Volunteers
REVI Pilot Feasibility Trial in Long-Term Care
This pilot study evaluates the feasibility, safety, and acceptability of an immersive virtual reality (VR) intervention designed to promote psychological well-being in older adults living in a long-term care facility.
- Conditions
- Psychological Well Being, Healthy Volunteers, Aging, Long-Term Care
- Trial name
- REVI (NCT07742137)
- Testing
- Active IVR, Passive IVR
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Liver Transplantation, Liver Transplantation in Long-term
Immunosuppressant Withdrawal Based on Parenchymal Chimerism in the Liver Transplantation
The goal of this clinical trial is to learn whether liver parenchyma chimerism can represent a chievement of operational tolerance in liver transplantation recipients.
- Trial name
- NCT07735650
- Testing
- liver biopsy, Immunosuppression withdrawal, Immunosuppression minimization
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Elderly, Surgery
Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery
A majority of the elderly patients undergo surgery for malignant tumors. For these patients, postoperative tumor recurrence and metastasis are main factors that worsen long-term outcomes.
- Conditions
- Elderly, Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03012971
- Testing
- Dexmedetomidine supplemented morphine analgesia, Morphine analgesia
- Where
- 12 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Peking University First Hospital
Long Term Follow-Up, Transvaginal Cystocele Repair
Long Term Follow Up Of Transvaginal Cystocele Repair Using Four Armed Collagen Coated Polyester Mesh
This study aims to assess safety and efficacy of transvaginal repair of cystocele using four armed collagen coated polyester mesh beyond 5 years postoperatively.
- Conditions
- Long Term Follow-Up, Transvaginal Cystocele Repair, Four Armed Collagen, Polyester Mesh
- Trial name
- NCT07730749
- Testing
- transvaginal cystocele repair
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Long-term Tracheostomy Ventilated Patients
Effects of Vibrating Mesh Nebulisation in Patients on Long-term Tracheostomy Ventilation: a Pilot Randomised Crossover Trial
Assessment of the effects of vibrating mesh nebulisation versus jet nebulisation on respiratory function in patients with long-term tracheostomy ventilation: evaluating neural respiratory drive, breathing mechanics, cardiac…
- Trial name
- EVOLVE (NCT06834581)
- Testing
- Vibrating mesh nebuliser, Jet nebuliser
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment
China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）
Background: Although emergency surgery may reduce mortality in patients with severe spontaneous intracerebral hemorrhage (SSICH), the effectiveness and safety of surgical treatment among SSICH patients receiving long-term oral…
- Conditions
- Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, Complications
- Trial name
- NCT05975398
- Testing
- Emergency neurosurgery, Conservative treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Long Term Safety Following GM T Cell Therapy
A Safety and Efficacy Long-Term Follow-up Study of Adult Participants Treated With Gene Modified T Cells
This is a prospective study for the Long-Term Follow-Up (LTFU) of safety and efficacy of all participants exposed to gene modified (GM) T cell therapy in accordance with Health Authorities' guidance for participants treated with…
- Trial name
- NCT06798298
- Testing
- Non-interventional
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Regeneron Pharmaceuticals
Patient Reported Outcomes, Patient Satisfaction
Patient-reported Outcome and Patient-reported Experience After Status Epilepticus
Status epilepticus (SE) is a common life-threatening neurological emergency in which prolonged or multiple closely spaced seizures can result in long-term impairments.
- Conditions
- Patient Reported Outcomes, Patient Satisfaction, Long Term Outcomes, Status Epilepticus
- Trial name
- POSEIDON2 (NCT06100978)
- Where
- 19 sites in France
- Volunteers
- 145 people
- Sponsor
- Versailles Hospital
Long-Term Care Professionals, Dementia Knowledge and Attitudes
Digital Learning Technology for Dementia Care Training in Long-term Care Professionals
Dementia, including cognitive decline and behavioral and psychiatric symptoms of dementia (BPSD), presents a significant challenge to long-term care systems and family caregivers.
- Conditions
- Long-Term Care Professionals, Dementia Knowledge and Attitudes, Interprofessional Collaboration, Dementia Education Program
- Trial name
- NCT07679230
- Testing
- Dementia care education program, Routine education
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tunghai University
Long Term Efficacy and Safety
A Long-term Follow-up Trial of Patients Previously Treated With Imlifidase Prior to Kidney Transplantation and a Non-comparative Transplanted Patient Group
A prospective, post-authorisation long-term follow-up trial of patients previously treated with imlifidase prior to kidney transplantation, including a non-comparative concurrent reference cohort.
- Trial name
- PAES-LTFU (NCT05937750)
- Testing
- Imlifidase administered in the 20-HMedIdeS-19 (PAES) study, Best available treatment administered in the 20-HMedIdeS-19 (PAES) study
- Where
- 14 sites in Austria, Czechia and 5 more
- Volunteers
- 150 people
- Sponsor
- Hansa Biopharma AB
Cancer Surgery, Intraoperative Hypothermia
Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival
Intraoperative hypothermia is common in patients having major surgery and the compliance with intraoperative temperature monitoring and management remains poor.
- Conditions
- Cancer Surgery, Intraoperative Hypothermia, Targeted Temperature Management, Postoperative Delirium
- Trial name
- NCT06256354
- Testing
- Routine thermal management, Target temperature management
- Where
- 36 sites in China
- Volunteers
- 3,992 people
- Sponsor
- Peking University First Hospital
Safety and Potential Symptom Improvement Effects of Long Term Consumption of Plasma Activated Water in Fibromyalgia Patients
The Potential Application of Plasma-Activated Water in Fibromyalgia Patients
Fibromyalgia is a chronic syndrome characterized by widespread pain that is commonly observed in pain, rheumatology, or rehabilitation clinics. Previous studies have suggested a fibromyalgia prevalence rate of approximately 2%.
- Trial name
- NCT07659236
- Testing
- Plasma-Activated Water
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Long-term Health Conditions
An Acceptance and Commitment Therapy Psychoeducation Single Session Intervention on Childhood Anxiety for Carers of Children With a Long-Term Health Condition
The goal of this feasibility study was to assess the acceptability and feasibility of the ACT-based training package for carers of children with a long-term health condition (LTHC) who also experience anxiety.
- Trial name
- NCT07656220
- Testing
- Psychoeducation for anxiety
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of East Anglia
Risk Factors, Complication of Surgical Procedure
ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.
- Conditions
- Risk Factors, Complication of Surgical Procedure, Complication of Treatment, Complication of Anesthesia
- Trial name
- ACUTE (NCT05195697)
- Testing
- Observational study of different treatments and time to treatment
- Where
- Sweden
- Volunteers
- 3,000 people
- Sponsor
- Region Skane
Long-Term Care, Long-term Care Facility
Effect of Empathy-Based Program on Nursing Assistants in Long-term Care Facilities
This randomized controlled trial aims to explore the impact of an Empathy-Based Program on the level of empathy among nursing assistants in a long-term care facility.
- Trial name
- NCT07044492
- Testing
- Virtual Reality (VR) with Debriefing
- Where
- Taiwan
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
The Focus is to Develop a Closed-loop Control System for Anaesthesia in Vitroretinal Surgery, Surgery Due to Expansive Processes in Head, and Long-term Sedation
Modeling and Closed-loop Control of Depth of Anaesthesia
The study evaluates the effect of anaesthetic agents to depth of anaesthesia. An improved PK-PD model wil be developed that will provide the basis for understanding the mechanisms, simulating various scenarios and developing…
- Trial name
- NCT03569839
- Testing
- Propofol
- Where
- Slovenia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Long-Term Memory Decline, Mild Cognitive Impairment
Wayfinding Intervention and Long-Term Memory
Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment.
- Trial name
- Quest-Tablet (NCT05625425)
- Testing
- LabyrinthVR software, Labyrinth Tablet software, Labyrinth VR wireless
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco