Clinical trials: Long Covid 19
SARS-CoV2 Infection
Cellular Senescence and COVID-19 Long-Hauler Syndrome
The purpose of this study is to test if senescent cells and their secretome contribute to Long-Hauler Syndrome and if a clinical trial of senolytic drugs, which selectively eliminate senescent cells, should be initiated.
- Trial name
- NCT04903132
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Long COVID
Pre-probiotic Supplementation for Post-covid Fatigue Syndrome
The goal of this randomized controlled double-blind parallel-group interventional trial is to evaluate the effects of of dietary supplementation with a pre-probiotic on patient- and clinician-reported outcomes, and brain tissue…
- Trial name
- STOPPFATIQUE (NCT06013072)
- Testing
- Dietary Supplement: Experimental
- Where
- Serbia
- Volunteers
- 32 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Post-Acute COVID-19 Syndrome, COVID-19
Long COVID-19 Rehabilitation & Recovery Research Program
The purpose of the study is to assess the physiologic, immunologic, and mental health effects of an exercise and pulmonary rehabilitation program on patients with Long COVID-19 (LC).
- Trial name
- LC Rehab (NCT05398692)
- Testing
- On Site Exercise Rehabilitation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
COVID-19
Transcranial Direct Stimulation for Persistent Fatigue Treatment Post-COVID-19
Fatigue is common and disabling in patients with post-COVID syndrome. There is no treatment available at this moment, and fatigue has important consequences.
- Trial name
- STIMULATECOVID (NCT05252481)
- Testing
- Active tDCS
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Hospital San Carlos, Madrid
Long COVID
Prospective, Open-label Study of Seraph 100 in Patients With Prolonged COVID (PC)
This study will use a prospective, open, single-arm design, in which a group of 100 patients with a diagnosis of prolonged COVID, previously selected according to inclusion and exclusion criteria, and who have undergone informed…
- Trial name
- NCT06637800
- Testing
- Seraph® 100 Microbind® Affinity Blood Filter (Seraph 100)
- Where
- Mexico
- Sponsor
- ExThera Medical Corporation
SARS CoV-2 Post-Acute Sequelae
Antiviral Strategies in the Prevention of Long-term Cardiovascular Outcomes Following COVID-19: The paxloviD/Remdesivir Effectiveness For the prEvention of loNg coviD Clinical Trial
The DEFEND trial will be the world's first clinical trial to study the effectiveness of Paxlovid or Veklury in the prevention of cardiovascular post-acute sequelae of SARS-CoV-2 among hospitalized adults.
- Trial name
- DEFEND (NCT06792214)
- Testing
- Nirmatrelvir/ritonavir, Remdesivir
- Where
- 4 sites in Canada
- Volunteers
- 118 people
- Sponsor
- Mount Sinai Hospital, Canada
Long COVID, Long COVID Syndrome
Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation
The goal of this clinical trial is to test whether a type of rapid outpatient brain stimulation that uses magnetic fields, called accelerated intermittent theta burst stimulation (iTBS), can treat symptoms such as brain fog…
- Conditions
- Long COVID, Long COVID Syndrome, Long COVID-19 Syndrome, PASC
- Trial name
- MANIFEST (NCT06940609)
- Testing
- accelerated intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Long COVID Syndrome
A Fasting Pilot Study for Long COVID
Background Long COVID (LC) is a chronic multisystemic condition which substantially impact the quality of life. Despite the staggering burden of LC, there is still no effective treatment.
- Trial name
- NCT07418567
- Testing
- prolonged fasting
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Université de Sherbrooke
Long COVID
Exercise for Health in Patients With Post-acute Sequelae of COVID-19
Background: Many patients with COVID-19 present the so-called post-acute sequelae of COVID-19 such as fatigue, post-stress discomfort, dyspnea, headache, pain mental impairment, incapacity to perform daily physical tasks ant…
- Trial name
- EJerSA-COVID (NCT05848518)
- Testing
- Rehabilitation program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Campus docent Sant Joan de Déu-Universitat de Barcelona
Post-COVID-19 Syndrome, Postural Tachycardia Syndrome
VNS for Long-COVID-19
The goal of this proposed clinical case series is to evaluate the effect of a non-invasive vagus nerve stimulation paradigm on: 1) Symptom reporting via validated patient reported outcomes, and 2) objective clinical biomarkers of…
- Conditions
- Post-COVID-19 Syndrome, Postural Tachycardia Syndrome, Dysautonomia
- Trial name
- NCT05630040
- Testing
- Non-invasive vagus nerve stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
COVID-19
HEART Rate Variability Biofeedback in LOng COVID-19 (HEARTLOC)
Long COVID is a common but highly debilitating illness which develops after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19).
- Trial name
- HEARTLOC (NCT05228665)
- Testing
- Heart Rate Variability Biofeedback (HRV-B)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Leeds
COVID-19
CONFIDENT: Supporting Long-term Care Workers During COVID-19
The CONFIDENT Study is an online three-arm randomized trial that aims to help long-term care workers in the United States feel more confident about the Coronavirus Disease 2019 (COVID-19) vaccines.
- Trial name
- NCT05168800
- Testing
- Dialogue-Based Webinar, Social Media Website, Enhanced Usual Practice
- Where
- United States
- Volunteers
- 2,634 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
COVID-19
Health After Covid-19 in Tyrol
The aim of the regional online questionnaire is to better understand the pattern of acute infection and the time of recovery of various symptoms.
- Trial name
- NCT04661462
- Testing
- online survey
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Covid19
Rehabilitation for Patients With Persistent Symptoms Post COVID-19
A large proportion of persons who have had COVID-19 have reported persisted symptoms as fatigue and dyspnea months post infection which affect activities of daily living.
- Trial name
- NCT04836351
- Testing
- Concentrated rehabilitation for patients with persistent symptoms post COVID-19
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Western Norway University of Applied Sciences
Long COVID
A Web-based Platform to Improve Physical Function, Nutrition, and Mindfulness in Patients With Long COVID
Patients with COVID-19 may experience prolonged physical and psychological symptoms after weeks or months of the infection. This may be caused by a combination of factors including poor nutrition, low physical activity, and lack…
- Trial name
- BLEND (NCT05422924)
- Testing
- Web-based platform. (My Viva Plan)
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University of Alberta
Post-acute Sequelae of SARS-CoV-2 Infection
Cognitive-Sensorimotor Function in Long-COVID
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance.
- Trial name
- NCT06850350
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cognitive Decline, Cognitive Dysfunction
Open-label, Post-marketing, Prospective Study to Assess Impact of COVID-19 on Cognitive Function in Patients
The objective of this study is to compare the impact of the coronavirus disease (SARS-CoV-2, or COVID-19) on cognitive function in the population of patients who have been diagnosed, treated and recovered from the COVID-19…
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Brain Health, Post CoV-2 Syndrome
- Trial name
- COVID19 (NCT04950673)
- Testing
- Cognivue
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cognivue, Inc.