Clinical trials: Locomotor Activity
Cerebral Palsy
Activities-based Locomotor Training Program Versus Traditional Physical Therapy in Children With Cerebral Palsy
The purpose of this study is to investigate the impact of an intensive activities-based locomotor training program as compared to traditional physical therapy on activity, participation, and central and peripheral…
- Trial name
- NCT06352814
- Testing
- Activities-based locomotor training (physical therapy)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Baylor University
Alzheimers Disease, Mild Cognitive Impairment
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor…
- Trial name
- NCT06484244
- Testing
- 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
COVID-19
LOng COvid Multidisciplinary Consortium: Optimising Treatments and servIces Across the NHS (LOCOMOTION)
Background: Long Covid (LC) affects over one million people in the UK, it has various symptoms and impacts daily life. Although there are 83 LC clinics in England, most people have not had access to them, and waiting times to be…
- Trial name
- LOCOMOTION (NCT05057260)
- Testing
- No drug invervention
- Where
- United Kingdom
- Volunteers
- 7,000 people
- Sponsor
- University of Leeds
Peripheral Arterial Disease
Locomotion and Global Positioning System in Arterial Disease
The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although…
- Trial name
- Starter-GPS (NCT00485147)
- Testing
- Recording of GPS during a free walking in a public park
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Movement Disorders, Parkinson Disease
A Smartphone Based, Titrated Exercise Solution for Patients With Parkinson's Disease in Daily Life: Pilot Study
The aim of this pilot randomized controlled trial is to test whether it's feasible to increase participants' step counts within four weeks with a developed motivational smartphone application.
- Trial name
- STEPWISE (NCT06692387)
- Testing
- Step count increase with the use of a motivational application
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Spinal Cord Injuries
Overground Walking Program With Robotic Exoskeleton in Long-term Manual Wheelchair Users With Spinal Cord Injury
Many individuals with a spinal cord injury (SCI) use a wheelchair as their primary mode of locomotion. The prolonged non-active sitting time associated to this mode of locomotion contributes to development or worsening of…
- Trial name
- NCT03989752
- Testing
- Wearable Robotic Exoskeleton for Ambulation
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Cerebral Palsy
Intensive Activities-based Locomotor Training Program in Children With Cerebral Palsy
The goal of the proposed work is to investigate the impact of an intensive 3-week activities-based locomotor training (AB-LT) program on activity capacity, activity performance, and participation in children with cerebral palsy…
- Trial name
- NCT05867628
- Testing
- Activities-based locomotor training (physical therapy)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Baylor University
Simulation of Weightlessness by Anti-Orthostatic Long Term Bed Rest
Toulouse Male Long Term Bed Rest 2001-2002
Microgravity during space flight induces physiological changes that affect astronauts' health and performance. Space flight simulations such as prolonged bed rest can mimic some of these changes and provide study conditions that…
- Trial name
- NCT00311571
- Testing
- Ethidronate, Physical training
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre National d'Etudes Spatiales
Cerebral Vascular Accident
Analysis of the Psychometric Properties of Kinematic Parameters of Locomotion Measured by Inertial Units. Validation in Healthy Volunteers and Stroke Patients
Stroke is the leading cause of acquired disability in adults in France, and more than 500,000 French people are currently living with the after-effects.
- Trial name
- KAPP-IMU (NCT05104645)
- Testing
- Analysis of the walk, Analysis of the race, Unipodal and bipodal jumps on flat ground
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Gait, Locomotion
Effects of Heel Height on Gait Parameters
This observational study aims to investigate the effects of different shoe heel heights on gait parameters and pelvic kinematics in healthy adults aged 18-35 years.
- Trial name
- NCT07167472
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Type 2 Diabetes Mellitus
Impact of Muscle and Tendon Dysfunction in People With Type 2 Diabetes Mellitus
Diabetes is a chronic-degenerative metabolic disorder that has reached pandemic proportions mainly because of the increasing incidence and prevalence of type 2 diabetes mellitus (T2D).
- Trial name
- T2D_MTU (NCT05585502)
- Testing
- Training (minute oscillation stretching)
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Lower Limb Amputation
Identification of Limiting Factors in the Locomotor Activity of Individuals With Lower Limb Amputation:
The experience of amputation leads to a deterioration in quality of life, with undeniable somatic and functional repercussions. The result is a reduction in general mobility, increased metabolic energy requirements and a feeling…
- Trial name
- AMPUTEEFACT (NCT06415955)
- Testing
- None, pure observationnal study
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Parkinson Disease, COPD
The ADAPT-study: Measuring Physical Performance Using Wearable Sensors in Parkinson's Disease and COPD (ADAPT)
The aim of this study is to investigate whether a smartwatch can measure the physical capacity of patients with Parkinson's Disease and COPD in the physiotherapy practice and at home.
- Trial name
- ADAPT (NCT05756075)
- Testing
- Aerobic exercise training
- Where
- 28 sites in Netherlands
- Volunteers
- 154 people
- Sponsor
- Radboud University Medical Center
Spinal Cord Injuries
Transformation of Paralysis to Stepping
The main goal of the project is to develop multiple noninvasive neuromodulatory strategies to facilitate full weight bearing stepping overground in people with paralysis.
- Trial name
- NCT04105114
- Testing
- Buspirone, Non-invasive Spinal Cord Stimulation, Overground stepping
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Louisville
Stroke
Effects of a Provision of a Cane After Stroke
Previous studies failed to determine the real effects of the provision of a walking cane after a stroke, mainly due to biases related to their methodological designs.
- Trial name
- NCT03150979
- Testing
- Provision of a cane, Control
- Where
- 2 sites in Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of Minas Gerais
Rectal Cancer, Defect of Floor of Lesser Pelvis
Collagen Implant (Biological Mesh) Versus GM Flap for Reconstruction of Pelvic Floor After ELAPE in Rectal Cancer
The trial compares two different techniques for reconstruction of the lesser pelvic floor after an extended abdominoperineal excision for locally advanced rectal cancer.
- Trial name
- NEAPE (NCT01347697)
- Testing
- Reconstruction with an acellular porcine dermal collagen implant (biological mesh), Reconstruction with a gluteus maximus myocutaneous flap
- Where
- 8 sites in Finland, Sweden
- Volunteers
- 91 people
- Sponsor
- Umeå University
Stroke, Ischemic, Subacute Stroke
The Effect of BWSTT on Neuroendocrine Profile and Functional Recovery in Stroke Patients
The purpose of this study is to evaluate the impact of intensive Body Weight Support Treadmill Training (BWSTT) on the neuroendocrine system and functional recovery in patients during the subacute phase of ischemic stroke.
- Trial name
- NCT07443150
- Testing
- Body Weight Support Treadmill Training (BWSTT), Overground Training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Alzheimer Disease
Influence of Physical Exercise as Adjuvant Treatment in Patients With Alzheimer's Disease
The goal of this non-randomized clinical trial is to assess the effects of strength training in the physical function of Alzheimer's disease (AD) patients. The main question it aims to answer are: 1.
- Trial name
- NCT05862935
- Testing
- Supervised Physical Activity (AMRAP -As Many Repetitions As Possible): Phase 2, Supervised Physical Activity: Phase 1
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- European University Miguel de Cervantes
Spastic Hemiplegic Cerebral Palsy
Effect of Lower Extremity Modified Constraint-induced Movement Therapy on Locomotion in Children With Hemiplegia
To determine the effect of modified constraint-induced movement therapy on spatial and temporal gait parameters in children with hemiplegia.
- Trial name
- NCT07686809
- Testing
- Modified constraint-induced movement therapy, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University