Clinical trials: Locomotion
Hip Osteoarthritis, Indication for Total Hip Replacement
Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis.
The investigators believe that the application of non-linear methods of analysis using the ganglion and neural network technique will make it possible to analyse all of the complex data obtained in patients with hip…
- Trial name
- NCT02042586
- Testing
- Analysis of movement before total hip replacement, Analysis of movement after total hip replacement
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Spinal Cord Injuries
Transcutaneous Spinal Stimulation and Exercise for Locomotion
Growing evidence indicates that electrical spinal cord stimulation improves motor functions both immediately and over the long term via modulating the excitability of spinal circuitry in patients with spinal cord injury.
- Trial name
- NCT03509558
- Testing
- Transcutaneous spinal stimulation, Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Alzheimers Disease, Mild Cognitive Impairment
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor…
- Trial name
- NCT06484244
- Testing
- 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Stroke, Chronic Stroke
Quantifying the Role of Sensory Systems Processing in Post-Stroke Walking Recovery
Despite current walking rehabilitation strategies, the majority of stroke survivors are unable to walking independently in the community and remain at increased risk of falls.
- Conditions
- Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic
- Trial name
- BLT2 (NCT04553198)
- Testing
- Backward Locomotion Treadmill Training (BLTT)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Cincinnati
Craniocerebral Trauma
The Acute Effect of Boxing on Balance, Neuropsychological, and Visual Functions
Prior research has investigated the effect of repetitive head trauma as it relates to physiological and psychological function. Boxing is one particular sport which predisposes athletes to a large amount of head impacts.
- Trial name
- NCT02442882
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Alzheimer Disease
Influence of Physical Exercise as Adjuvant Treatment in Patients With Alzheimer's Disease
The goal of this non-randomized clinical trial is to assess the effects of strength training in the physical function of Alzheimer's disease (AD) patients. The main question it aims to answer are: 1.
- Trial name
- NCT05862935
- Testing
- Supervised Physical Activity (AMRAP -As Many Repetitions As Possible): Phase 2, Supervised Physical Activity: Phase 1
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- European University Miguel de Cervantes
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Stroke
Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke
The objective of this study is to determine the optimal training intensity and the minimum training duration needed to maximize immediate improvements in walking capacity in chronic stroke.
- Trial name
- NCT03760016
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Cincinnati
Ankylosing Spondylitis
Function, Locomotion, Measurement and Inflammation
FoLoMI is a pilot study in which the investigators will seek to determine if gait spatio-temporal and kinematic parameters can explain the evolution of a functional score, the Bath Ankylosing Spondylitis Functional Index (BASFI)…
- Trial name
- FoLoMI (NCT03761212)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Grenoble
Exoskeleton Device, Locomotion
Investigation of the Effects of Robot Assisted Gait Training With Virtual Reality on Cognitive Functions in Stroke Patients
It was planned to examine the effects of robot-assisted walking training supported by virtual reality on cognitive functions, quality of life and activities of daily living in individuals with subacute stroke.
- Conditions
- Exoskeleton Device, Locomotion, Stroke
- Trial name
- NCT05614141
- Testing
- Lokomat Augmented Performance Feedback, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara Yildirim Beyazıt University
Multiple Sclerosis
Biomechanical Characterization of the Locomotion in Multiple Sclerosis Patients
Multiple sclerosis (MS) is an inflammatory chronic disease of the central nervous system. Patients are suffering from balance and gait impairments at the early stage of the disease.
- Trial name
- WALKING-SEP (NCT03756142)
- Testing
- Motion Analysis
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Stroke
Robotic Exosuit Augmented Locomotion (REAL)
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL (NCT04818424)
- Testing
- Soft exosuit, Gait training without exosuits
- Where
- 3 sites in United States
- Sponsor
- Lou Awad, PT, DPT, PhD
Stroke
HIT-Stroke Trial 2
People who had a stroke at least 6 months prior and who still have difficulty with walking will each be randomly assigned to receive either moderate or vigorous intensity walking exercise.
- Trial name
- HST2 (NCT06268041)
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 156 people
- Sponsor
- University of Cincinnati
SMA
A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SMA (Spinal Muscular Atrophy) Patients
A head-to-head study comparing the functional value of two models of robotically assisted rehabilitation in patients with SMA. A single-center, randomized, single-blinded, comparative study of Robotically Assisted Verticalization…
- Trial name
- SMArt (NCT06322654)
- Testing
- Robotically Assisted Locomotion, Robotically Assisted Verticalization
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Wiktor Dega University Orthopedic and Rehabilitation Hospital
Cerebral Palsy, Spastic
Associated Disorders of Locomotion and Postural Control of Axial Segments in Cerebral Palsy
Gait abnormalities, which occur in Cerebral Palsy (CP), are characterized usually by a toe-to-floor or a plantar-to-floor initial contact (equinus gait), followed by an early braking of the tibia's forward progression (during…
- Trial name
- NCT04287673
- Testing
- Rehabilitation involving strongly the trunk
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Chronic Low-back Pain, Walking
Locomotion Strategies of Low Back Pain Patients in a Dynamic Environment
The biomechanical parameters studied in non-specific chronic low back pain patients in a locomotion task have so far focused on straight line walking.
- Trial name
- NCT05851118
- Testing
- Quantified analysis of walking during a crossing task between two walkers
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Locomotion Disorder, Neurologic
Non Motoric Reactions in Vojta Reflex Locomotion
Monitoring of non-motor manifestations of reflex locomotion according to Professor Vojta in laboratory conditions on healthy woman probands.
- Trial name
- VojtaRL (NCT06224491)
- Testing
- Reflex locomotion according to Vojta
- Where
- Czechia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Spinal Cord Injury
Xo-Motion R Exoskeleton in SCI-Adoption Study
After spinal cord injury (SCI), many people lose their ability to walk and do not have access to equipment and assistance that could help them regain functional abilities.
- Trial name
- NCT07380516
- Testing
- XoMotionR- assisted locomotor training
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Stroke, Cerebral Vascular Disorders
Discrete Versus Rhythmic Gait Training
The objective of this study is to compare the effects of novel versus standard locomotor training using a robotic gait orthosis (LT-RGO) after stroke.
- Trial name
- NCT02650440
- Testing
- Novel Protocol, Standard Protocol
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Thais Amanda Rodrigues