Clinical trials: Local Anesthesia Infiltration
Dental Caries, Reversible Pulpitis
Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syringe in Pediatric Patients
This randomized controlled trial is conducted on pediatric dental patients to compare the effectiveness of local anesthesia administered using a dental anesthesia injector device versus the traditional syringe method.
- Trial name
- NCT07101068
- Testing
- Dental Anesthesia Injector, conventional syringe
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Volunteers
Local Anesthetic Properties of Neosaxitoxin
The purpose of this study is to evaluate the local anesthetic properties of neosaxitoxin in humans
- Trial name
- NCT00273065
- Testing
- Neosaxitoxin
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chile
Local Anesthesia
Anesthetic Efficacy of %4Alexadricaine Versus %2 Mepicaine-L in Children
The aim of the present study is to evaluate and compare the anesthetic efficacy of Alexadricaine versus Mepecaine-L infiltration anesthesia in children during extraction of badly decayed or unrestorable maxillary first primary…
- Trial name
- NCT04477317
- Testing
- 4% Articaine Hydrochloride with 1:100,000 Adrenaline, 2% Mepivacaine Hydrochloride with 1:20,000 Levonordefrin
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Femoroacetabular Impingement
PRCT of FICB vs LAI for Hip Arthroscopy
A prospective randomised controlled trial involving patients undergoing hip arthroscopy. Participants were randomised to receiving either Fascia Iliaca Compartment Block (FICB) or Local Anaesthetic Infiltration (LAI) of the…
- Trial name
- NCT02702661
- Testing
- Fascia Iliaca Compartment Block (FICB), Local Anaesthetic Infiltration (LAI), Levobupivacaine
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Pain, Postoperative
Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study
The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound…
- Trial name
- NCT00508092
- Testing
- local anesthetic administration
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Royal Berkshire NHS Foundation Trust
Local Anesthetic Infiltration, Topical Anesthesia
Topical Cryoanesthesia Versus Benzocaine in Pediatric Dentistry
This clinical study tested and compared two ways (cold-base technique or "cryoanesthesia" and conventional benzocaine gel) to reduce pain from dental injections in children.
- Conditions
- Local Anesthetic Infiltration, Topical Anesthesia, Pain Perception
- Trial name
- No acronym (NCT07351383)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Injection Pain, Local Anesthesia Infiltration
Clinical Trial Comparing Pain Perception in Children Using Two Different Local Anesthesia Tools
The goal of this clinical study is to learn whether the Super Pen (SP) device can reduce pain during local anesthesia (LA) infiltration for primary teeth compared to the conventional syringe (CS) in children aged 6-12 years.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pediatric Patient
- Trial name
- NCT07292194
- Testing
- super pen
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Lamis D. Rajab
Local Anaesthesia
Buzzy System Compared to Topical Anaesthesia During Infiltration Injection in Children.
Aim of the study is to test the effect of Buzzy System (vibrating device) compared to topical anaesthesia on pain reduction during injection of infiltration anaesthesia in children.
- Trial name
- NCT05083975
- Testing
- Buzzy System, Topical anesthetic, 1.8 ml of 4% articaine hydrochloride with epinephrine 1:100,000
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anxiety, Pain
Comparison of Five Anesthetic Delivery Systems for Palatal Infiltration
This study is a randomized clinical trial evaluating five different anesthetic delivery systems for palatal infiltration in adults undergoing maxillary molar extraction.
- Conditions
- Dental Anxiety, Pain, Dental, Palatal Anesthesia
- Trial name
- PAL-INJECT (NCT07184879)
- Testing
- Conventional Dental Syringe, Spring-Activated Syringe (PCJ, PAROJECT™), Needle-Free Jet Injector (NFI, Comfort-in™)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sercan Küçükkurt
Cold Atmospheric Plasma, Dental Anesthesia
Effect of Cold Atmospheric Plasma on Patient Comfort During Dental Anesthesia
This study aims to investigate the effectiveness of cold atmospheric plasma, a laser-like biophysical method, in reducing injection pain experienced during local infiltration anesthesia in dental treatments.
- Trial name
- NCT07288125
- Testing
- Cold Atmospheric Plasma, No pretreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Pain, Postoperative, Pain, Acute
External Oblique Intercostal Block in Laparoscopic Cholecystectomy
Adequate postoperative pain management is essential for improving patient comfort and recovery after laparoscopic cholecystectomy.
- Conditions
- Pain, Postoperative, Pain, Acute, Opioid Use
- Trial name
- NCT07164664
- Testing
- External Oblique Intercostal Block, Port-Site Infiltration, ıv morphine PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain, Subcostal Transversus Abdominis Plane Block
Effects of Subcostal TAP Block and Local Anesthetic Infiltration After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy surgery is an intra-abdominal surgery that is frequently used in the treatment of gallbladder-related pathologies.
- Conditions
- Postoperative Pain, Subcostal Transversus Abdominis Plane Block, Gall Bladder Disease
- Trial name
- NCT05769881
- Testing
- Ultrasound guided subcostal transversus abdominis plane block, Wound site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Pain, Postoperative, Anesthesia, Local
Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration
This study evaluates differences in how administering liposomal bupivacaine via two different methods affects postoperative pain control in laparoscopic abdominal surgery patients.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Anesthesia; Functional, Anesthesia
- Trial name
- NCT03927326
- Testing
- Exparel 266 MG Per 20 ML Injection
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain Perception, Local Anesthesia
Pain Perception Comparison of Computerized vs Conventional Injection Methods
This study was conducted to a Comparison of Pain Perception for Nerve Block and Infiltration Injection Using the Conventional Method and Two Computerized Control Systems.
- Trial name
- NCT06129162
- Testing
- Conventional Syringe, STA Single Tooth Anesthesia® System., Star Pen anesthesia device.
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Healthy Participants, Tooth Extraction
Application Of Dentapen In Dental Local Infiltration Anesthesia
The goal of this clinical study is to compare patients' self-reported pain and mental stress during infiltration anesthesia between conventional syringe and Dentapen.
- Conditions
- Healthy Participants, Tooth Extraction, Orthodontic Patients
- Trial name
- NCT07431801
- Testing
- computer controlled local anesthesia delivery device (Dentapen), Control
- Where
- Vietnam
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Son Hoang Le
Local Anesthesia Infiltration
Efficacy of Facial Massager in Reducing Intra Oral Injection Pain in Pediatric Patients
Abstract Background: Local anesthesia is a primary source of anxiety in pediatric dentistry. Objective: To evaluate if mechanical vibration from a low-cost facial massager reduces pain and anxiety during injections using the Gate…
- Trial name
- NCT07682181
- Testing
- Facial T massager, Topical Benzocaine 20%
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Hospital, India
Efficiency and Safey of Radial Artery Cannulation
Novel Local Infiltration Anesthesia for Radial Artery Cannulation.
This clinical trial aims to compare the pain scores and cannulation success rates of conventional, bar-shaped, and V-shaped local infiltration anesthesia in participants' radial artery cannulation.
- Trial name
- NCT05735132
- Testing
- Conventional Line-blocking, Bar-blocking, V-blocking
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Postoperative Pain
Comparative Study of the Analgesic Effect of Spinal Anesthesia or Infiltration Anesthesia for Hemorrhoidectomy
Background and Objectives: Postoperative analgesia and early recovery are relevant for hospital discharge after hemorrhoidectomy.
- Trial name
- NCT02839538
- Testing
- Local Infiltration, Subarachnoidal block
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Anesthesia, Local, Needle Phobia
Needle-free Dental Anesthesia
Many patients experience pain and anxiety from traditional needle anesthesia and may avoid necessary dental treatments. The needle-free liquid jet injection(NFLJI) could solve these problems.
- Trial name
- NCT04493528
- Testing
- Meso-Jet, 2% lidocaine(xylocaine), Needle,2% lidocaine(xylocaine)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre