Clinical trials: Local Anaesthetic Complication
Fractured Neck of Femur, Postoperative Pain
Postoperative Analgesia for Fractured Neck of Femur With Periarticular Infiltration of Local Anaesthetic
The purpose of this study is to determine that periarticular levobupivacaine infiltration after surgical fixation of fractured neck of femur will improve the early postoperative pain sensation.
- Trial name
- NCT02057601
- Testing
- Levobupivacaine infiltration group
- Where
- Ireland
- Volunteers
- 37 people
- Sponsor
- Cork University Hospital
Postoperative Pain, Weakness, Muscle
Periarticular Infiltration of Local Anesthetics Versus Pericapsular Nerve Group Block for Total Hip Replacement
This randomized trial is set out to compare the postoperative strength preservation capacity of local infiltration anesthesia (LIA) and pericapsular nerve group (PENG) block after performing a primary total hip arthroplasty…
- Conditions
- Postoperative Pain, Weakness, Muscle, Analgesia, Motor Activity
- Trial name
- NCT05087862
- Testing
- Ultrasound-guided pericapsular nerves group of the hip block, Pericapsular local anesthetic infiltration of the hip
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Postoperative Pain
Different Volumes of Local Anesthetics in Thoracolumbar Interfascial Plane Block
Ultrasound-guided thoracolumbar interfascial plane block (TLIP)was first described in 2015 by Hand et al which also target the dorsal rami of the thoracolumbar nerves as they pass through the paraspinal musculature(between the…
- Trial name
- NCT05276908
- Testing
- Thoracolumbar interfascial plane block (TLIP)Technique, Anesthetic Management, Bupivacaine Injection 10ml
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Regional Anesthesia Morbidity, Pain, Postoperative
Randomized Trial of Erector Spinae Plane Block Using Liposomal Bupivacaine Versus Bupivacaine Hydrochloride on Quality of Recovery for Video-assisted Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) has emerged as the standard surgical modality for pulmonary tumor. Compared with open thoracotomy, VATS is associated with reduced surgical trauma, attenuated postoperative pain, and a…
- Trial name
- LB-ESPB (NCT07141667)
- Testing
- Erector spinae plane block with liposomal bupivacaine, Erector spinae plane block with bupivacaine HCL
- Volunteers
- 80 people
- Sponsor
- RenJi Hospital
Pain, Postoperative
Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
Effective post surgical pain control in patients undergoing unilateral deep inferior epigastric perforator (DIEP) free flap reconstruction.
- Trial name
- NCT04284930
- Testing
- Depobupivacaine, OnQ pump, 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Post-operative Pain, Colon Cancer
The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery
The purpose of the study is to evaluate the effect of Exparel on pain control and patient outcome after colon resection. The investigators will evaluate the clinical course of the patients who receive exparel as compared to the…
- Conditions
- Post-operative Pain, Colon Cancer, Diverticulitis
- Trial name
- NCT02052557
- Testing
- Bupivacaine, Bupivacaine liposome suspension
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Des Moines University
Pain, Postoperative
Erector Spinae Plane Block With Ropivacaine for Major Upper Abdominal Surgery
Prospective, single-centre, randomized, controlled, open-label, evaluator-blinded, superiority trial.
- Trial name
- NCT04702685
- Testing
- Ropivacaine
- Where
- Kazakhstan
- Volunteers
- 50 people
- Sponsor
- Nazarbayev University Medical Center
Local Anesthetic Complication
Evaluation of the Anti-anaesthetic Effects of Low-Level Laser Therapy on Children's Soft Tissue
Evaluate the effect of the photobiomodulation mode of the diode laser on the anaesthetic area and find the best parameter that would accelerate the withdrawal of anaesthesia.
- Trial name
- laser (NCT06193460)
- Testing
- low-level laser therapy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hand Injury, Wrist Injury
Comparing Two Injection Sites of Local Anesthetic for Hand Surgery
The purpose of this study is to compare two different injection sites for local anesthesia in patients having hand surgery. The hypothesis is that subjects receiving injections around the three nerves of the forearm will provide…
- Conditions
- Hand Injury, Wrist Injury, Finger Injury
- Trial name
- NCT02112006
- Testing
- 0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Herpes Zoster, Neuralgia
Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain
This study is a randomized, open-label multi-center evaluation of the tolerability of treatment with NGX-4010 in conjunction with pre-patch topical application of one of three 4% lidocaine-based local anesthetic products.
- Conditions
- Herpes Zoster, Neuralgia, Pain, HIV Infections
- Trial name
- NCT00082316
- Testing
- Capsaicin Dermal Patch
- Where
- 17 sites in United States
- Sponsor
- NeurogesX
Head and Neck Cancer, Free Tissue Transfer
Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps
Head and neck oncologic surgery often requires the use of free tissue transfer, or microvascular reconstruction, to reconstruct defects created by tumor resections.
- Trial name
- NCT03349034
- Testing
- Ropivicaine, Local Saline Infusion
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Disorders, Regional Anesthesia Morbidity
Transversus Abdominis Plane Blocks With and Without Dexamethasone
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
- Conditions
- Colorectal Disorders, Regional Anesthesia Morbidity, Analgesia, Local Anesthetic Complication
- Trial name
- TAP-DEX (NCT05432934)
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Magnesium Sulfate, Local Anesthetic
Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy
We aim to study the effect of adding magnesium sulfate as an adjuvant to the local anesthetic used in the combined Pectoralis Nerve Block II (PECS II) and stellate ganglion block for postoperative pain control in patients…
- Conditions
- Magnesium Sulfate, Local Anesthetic, Pectoral Nerve, Stellate Ganglion Block
- Trial name
- NCT06815887
- Testing
- Bupivacaine, Bupivacaine + Magnesium sulfate
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Postoperative Pain
COMPARISON OF INTRAOPERATIVE LOCAL ANESTHETIC APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN LAPAROSCOPIC CHOLECYSTECTOMY PATIENTS
Since 1987, laparoscopic cholecystectomy has become the standard procedure for gallbladder stones and lesions. Complications due to improvements in laparoscopy and increased surgical experience have decreased day by day, but…
- Trial name
- NCT03790007
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Postoperative
Cesarean Delivery and Post-operative Pain Management With Local Anesthesia
The use of .5% Bupivacaine with epinephrine at the time of skin closure in cesarean deliveries will decrease post-op pain.
- Trial name
- NCT00298571
- Testing
- .5% bupivacaine with epinephrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT04637386
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Complication of Anesthesia
Incidence and Etiology of Complications Associated With Peripheral Nerves Blocks
Procedures performed under regional anesthesia, especially peripheral nerve blocks (PNB) have increased markedly in recent decades. However, like any technical procedure, these techniques carry an implicit risk of complications.
- Trial name
- CARE (NCT05682300)
- Testing
- peripheral nerve block
- Where
- Spain
- Volunteers
- 1,390 people
- Sponsor
- Hospital del Rio Hortega
Postoperative Pain
Analgesic Effectiveness of PENG Block in Programmed Hip Arthroplasty Surgery
The intra- and peri-articular infiltration of local anaesthetics realized at the end of total hip arthroplasty surgeries is an effective analgesic technique, but it can be insufficient to manage the possibly intense postoperative…
- Trial name
- THAPeng (NCT04650100)
- Testing
- ultrasound-guided PENG bloc realized before surgery
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Toulouse
Postoperative Complications
Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with…
- Trial name
- NCT02962024
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma Adel El sherif,MD