Clinical trials: Living Donor Nephrectomy
Postoperative Pain, Kidney Transplant; Complications
Thread Embedding Acupuncture vs Sham on Acute Pain and Quality of Life After Laparoscopic Nephrectomy of Living Donor
This randomized, double-blind controlled study aims to evaluate the effectiveness of thread implantation acupuncture at EX-B2 L1 in reducing postoperative pain and improving quality of life in patients undergoing laparoscopic…
- Trial name
- NCT07243301
- Testing
- Thread implantation acupuncture
- Where
- Indonesia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
End Stage Kidney Disease
Evaluation of a Website on Living Kidney Donation for Hispanics
The purpose of this study is to increase understanding about living kidney donation (LKD) among Hispanic/Latino patients and public by increasing knowledge and positive attitudes about LKD.
- Trial name
- NCT01859871
- Testing
- Website Intervention
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Living Kidney Donation, Preoperative Anxiety
Preoperative Psychotherapy and Its Effects on Anxiety, Hemodynamics, and Pain in Living Kidney Donors
Chronic kidney failure is a condition in which the kidneys progressively lose their ability to filter waste, maintain fluid and electrolyte balance, and support essential physiological functions.
- Conditions
- Living Kidney Donation, Preoperative Anxiety, Postoperative Pain
- Trial name
- PREPSY-KD (NCT07261917)
- Testing
- Preoperative Psychiatric Consultation, No Intervention: Standard Preoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Patients Awaiting a Living Kidney Donation
Desensitization With Bortezomib Before a Living Kidney Donation
The investigators plan to study the role of bortezomib for desensitizing patients awaiting a living kidney donation who have a titer of Donor Specific anti human leucocyte antigen (HLA) Antibody (DSA) between 1000 and 3000 MFI…
- Trial name
- VELDON (NCT01842074)
- Testing
- Bortezomib
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Organ Donor
Healthcare Access and Utilization Among Living Kidney Donors
This is a mailed survey to persons who served as living kidney donors at Saint Barnabas Medical Center. The experimental component of this study (the clinical trial) is a randomized trial of two monetary incentives for the living…
- Trial name
- NCT01009125
- Testing
- $2 cash, $5 cash
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- St. Barnabas Medical Center
Kidney Transplantation
Medical Economic Evaluation and of Quality of Life of the Kidney Living Donors.
The main objective of this multicentre study is to conduct the evaluation of cost-efficiency of various techniques of kidney taking with regard the quality of life of the kidney living donors.
- Trial name
- DOVIREIN (NCT02830568)
- Testing
- open donor nephrectomy, standard and hand-assisted laparoscopic donor nephrectomy, laparoscopic robotic-assisted nephrectomy
- Where
- 24 sites in France
- Volunteers
- 268 people
- Sponsor
- Central Hospital, Nancy, France
Kidney Disease, Chronic, Myocardial Dysfunction
Coronary Microvascular Dysfunction in Chronic Kidney Disease
This is an observational study assessing coronary microvascular function in healthy controls with normal kidney function, living kidney donors, pre-dialysis patients with chronic kidney disease stage 5 and patients on peritoneal…
- Trial name
- CRIB-FLOW (NCT04014127)
- Testing
- Coronary flow reserve assessment, Sphygmocor, Electrocardiogram
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Living Renal Donor
Renal Donor Comparison of Outcomes: Hand Assist Versus Laparoscopic Nephrectomy
This study is designed to look at outcomes of patients who have undergone hand assisted laparoscopic donor nephrectomy versus totally laparoscopic donor nephrectomy.
- Trial name
- NCT00460889
- Testing
- donor nephrectomy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Nephrectomy
Recovery of Short-term Renal Function in Post-transplant Patients Living Donor
Objectives: To describe and analyze the perioperative and functional evolution of short-term renal graft in patients with kidney transplantation from a live donor, comparing three surgical techniques for obtaining kidney graft…
- Trial name
- NCT03717259
- Testing
- Open nephrectomy, Hand-assisted laparoscopic nephrectomy, Laparoscopic nephrectomy
- Volunteers
- 508 people
- Sponsor
- Instituto Mexicano del Seguro Social
Living Kidney Donation
Vascular Remodeling After Living Kidney Donation Study
Vascular evaluation of candidates to living kidney donation is important because there is an increased risk of end stage renal disease and cardiovascular disease after donation.
- Trial name
- EUGENIA (NCT05073913)
- Testing
- Vascular remodeling characterization
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infection
Prophylaxis Of Wound Infections- Antibiotics in Renal Donation
The aim of this study is to see whether antibiotics given at the start of laparoscopic kidney donation surgery prevent infection.
- Trial name
- POWAR (NCT02089568)
- Testing
- Co-Amoxiclav, Normal Saline
- Where
- United Kingdom
- Volunteers
- 284 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Living Kidney Donation, Hypertension
Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy
The goal of this observational study is to learn if PRAT thickness is a marker of visceral obesity and its influence on donors' kidney function and blood pressure in living kidney donors.
- Conditions
- Living Kidney Donation, Hypertension, Nephrectomy
- Trial name
- ProActive (NCT06886087)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Living Donor Nephrectomy
Scrotal Surgery After Laparoscopic Donor Nephrectomy
This study will examine whether laparoscopic nephrectomy is associated with a higher long-term risk of receiving scrotal surgery in male living kidney donors compared to male nondonors from the general population who have similar…
- Trial name
- NCT06716723
- Testing
- Nephrectomy
- Where
- Canada
- Volunteers
- 9,878 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Transplant, Kidney Donor
Transforming Curiosity Into Donation
This is a multi-step study that will first create a preliminary living donor drop-out risk index (LD-DROP) by retrospectively identifying factors that contribute to the discontinuation of living donor evaluation.
- Conditions
- Kidney Transplant, Kidney Donor, Drop Out, High Risk
- Trial name
- NCT07793890
- Testing
- Living Kidney Donor Support
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
End Stage Renal Disease
Explore Transplant @Home Within Kaiser Permanente Southern California
Today, there are 25 million Americans with chronic kidney disease (CKD) and 660,000 patients in full kidney failure, the final CKD stage, known as end stage renal disease (ESRD).
- Trial name
- NCT03389932
- Testing
- Patient-Guided
- Where
- United States
- Volunteers
- 977 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Living Donors, Nephrectomy
Conventional Laparoscopic Versus Laparoendoscopic Single Site Donor Nephrectomy in Living Donor Kidney Transplantation
Laparoscopic nephrectomy (removal of the kidney) is the most common procedure for people donating a kidney to be used for living donor kidney transplantation.
- Conditions
- Living Donors, Nephrectomy, Kidney Transplantation, Surgery, Laparoscopic
- Trial name
- NCT01236326
- Testing
- Laparoendoscopic single site donor nephrectomy, Conventional laparoscopic donor nephrectomy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Weill Medical College of Cornell University
Living Kidney Donation, Living Kidney Donor
Long-Term Risk of Gout in Living Kidney Donors
This population-based, matched, retrospective cohort study will evaluate the long-term risk of gout among living kidney donors compared with matched healthy nondonors, using linked administrative health care databases from…
- Conditions
- Living Kidney Donation, Living Kidney Donor, Gout, Gout and Hyperuricemia
- Trial name
- NCT07546643
- Testing
- Living kidney donation
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain, Renal Transplantation
Intravenous Lignocaine Infusion in Laparoscopic Donor Nephrectomy
Background: Administration of morphine as boluses or via a patient controlled analgesic device (PCA) has been the standard practice for donors after nephrectomy.
- Conditions
- Postoperative Pain, Renal Transplantation, Morphine Adverse Reaction
- Trial name
- NCT04052867
- Testing
- Lignocaine, Normal saline
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Postoperative Pain
Single-shot TAP Block vs Continuous TAP Block
The purpose of this study is to determine whether continuous transversus abdominis plane (TAP) block is superior to single shot TAP for postoperative pain after laparoscopic donor nephrectomy
- Trial name
- TAP (NCT02475031)
- Testing
- TAP-C, TAP-S
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Indiana University
Nephrectomy,Kidney Donation
A Comparison of Kidney Function After Nephrectomy in Living Donors Under Sevoflurane and Desflurane Anesthesia
Living-donor kidney transplantation has been considered as the best treatment for patients with end-stage renal disease (ESRD). Kidney donation from living donors has been performed widely under their noble humanity and a belief…
- Trial name
- NCT01549990
- Testing
- Sevoflurane, desflurane
- Where
- South Korea
- Volunteers
- 236 people
- Sponsor
- Yonsei University