Clinical trials: Lipodystrophy
HIV-Associated Lipodystrophy Syndrome, Cardiovascular Disease
HIV Infection And Metabolic Abnormalities Protocol 1 (HAMA001)
This is a prospective, non-randomised, 48 week study of the effect of protease inhibitor (PI) containing and non-PI containing antiretroviral regimens on the expression of adipocyte specific genes, protein levels and cellular…
- Trial name
- NCT00192660
- Testing
- Lamivudine, Stavudine, Didanosine
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Nasolabial Folds, Lipoatrophy
Phase 1 Study to Assess the Safety and Tolerability of TAT4 Gel in Healthy Volunteers
This Phase 1, randomized, placebo-controlled, double-blind, healthy volunteer study tested the safety, tolerability, and plasma pharmacokinetics of two different concentrations of TAT4 Gel administered once daily to 50 cm2 of…
- Conditions
- Nasolabial Folds, Lipoatrophy, Lipodystrophy
- Trial name
- NCT02647853
- Testing
- TAT4 Gel concentration A, TAT4 Gel concentration B
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Topokine Therapeutics, Inc.
HIV Lipodystrophy
Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome
The purpose of this study is to determine whether patients with HIV lipodystrophy (fat wasting) benefit from taking the combination of two drugs, one insulin sensitizer (either metformin or pioglitazone, both diabetes drugs) and…
- Trial name
- NCT00362440
- Testing
- Leptin, Pioglitazone or metformin
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Lipodystrophy
Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management
This study aims to compare the hemodynamic parameters, postoperative plethysmography variability index, the total amount of postoperative intravenous fluid administration needed, and the urine output of two methods of fluid…
- Trial name
- NCT05930106
- Testing
- Intraoperative fluid ratio, Carotid Artery Doppler Peak Velocity Variation
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TJ Plast Advanced Center for Plastic Surgery
Healthy, Lipodystrophy, Familial Partial
Lipodystrophy and Fat Metabolism During Exercise
Mandibular dysplasia with deafness and progeroid features (MDP) syndrome is a rare genetic metabolic disorder that causes lipodystrophy: the inability of the body to store subcutaneous adipose tissue (fat under the skin).
- Trial name
- FAT (NCT04056000)
- Testing
- Caffeine, High-carbohdyrate breakfast, 60-minutes of steady state exercise
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Exeter
Lipodystrophy, Obesity
Adipocyte, Insulin-resistance and Immunity : Evaluation of Interleukin-7 in Lipodystrophy, Diabetes and Obesity
White adipose tissue-related diseases spread from excess (obesity) to lack (lipoatrophies) through aberrant distribution (lipodystrophies), these 3 different disorders being paradoxically able to induce a metabolic insulin…
- Conditions
- Lipodystrophy, Obesity, Type 2 Diabetes
- Trial name
- IL-7norm (NCT01784289)
- Where
- 5 sites in France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille