Clinical trials: Lipedema
Lipedema
Characteristics of Pain in Women With Lipoedema
This observational study will seek to investigate the following questions in women with lipoedema: pain characteristics, intensity and patterns of pain the relationships between the characteristics, intensity and patterns of pain…
- Trial name
- NCT05114317
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Glasgow Caledonian University
Lipedema, Inflamation
Investigation of Systemic Inflammation Markers in Lipedema
The aim of this study is to evaluate systemic inflammation in individuals with lipedema using hematological and biochemical inflammation indices and to examine the relationship between these indices and clinical findings.
- Conditions
- Lipedema, Inflamation, Inflammation Biomarkers, Obesity & Overweight
- Trial name
- NCT07787234
- Testing
- Clinical parameters, Laboratory parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Lipedema
The Relationship Between Central Sensitization, Pain, and Psychosocial Factors in Individuals With Lipedema
This cross-sectional study will include women aged 18-75 with clinically diagnosed lipedema and healthy controls. Sociodemographic and clinical data will be collected, and participants will complete the Central Sensitization…
- Trial name
- NCT07240285
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lipedema, Secondary Lymphedema
Complete Decongestive Therapy With Negative Pressure for Lipedema and Lymphedema Therapy
This study is designed to investigate the therapy outcomes from routine physical therapy in persons with lipedema and secondary limb lymphedema.
- Trial name
- NCT03634462
- Testing
- CDT with graded negative pressure
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Lipedema, Osteoporosis
The Relationship Between Lipedema and Osteoporosis
The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema.
- Trial name
- NCT07779603
- Testing
- DXA
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema
Complex Decongestive Applications in Patients With Lipedema
Lipedema is a rare condition which almost exclusively affects women. The disease is characterized with bilateral, symmetric abnormal accumulation of subcutaneous fat and is often mistaken for simple obesity.
- Trial name
- NCT04492046
- Testing
- Manual Lymph Drainage, Bandaging
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Gazi University
Lipedema, Healthy
Muscle Strength, Muscle Endurance, Lower Extremity Function, Aerobic Capacity, Pressure Pain Threshold and Edema in Women With Lipedema
Lipedema is a chronic progressive disease that causes disproportionate, painful extremities with abnormal fat distribution. Lipedema is known to cause physical and psychosocial disorders in individuals, but there are very limited…
- Trial name
- NCT06866847
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Lipedema, Magnesium
Serum Magnesium Levels in Patients Diagnosed With Lipedema
Female patients diagnosed with lipedema will be divided into two groups based on their Pittsburgh Sleep Quality Index (PSQI) scores: PSQI ≤ 5 and PSQI > 5.
- Trial name
- NCT07779577
- Testing
- Magnesium
- Volunteers
- 128 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema, Metabolism
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema
Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid.
- Trial name
- Lipedema (NCT03271034)
- Testing
- Weight loss
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Lipedema
Extracorporeal Shock Wave Therapy in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder characterized by pain, tenderness, disproportionate fat accumulation, and impaired quality of life.
- Trial name
- LIPO-ESWT (NCT07683559)
- Testing
- Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Lipedema, Pain
Effect of Systemic and Local Ozone Therapy in Lipedema
Lipedema is a disease characterized by enlargement of the subcutaneous tissue and is observed only in the female population. Recently, the inflammatory cascade has been suggested to be the initiator of lipoedema and to play a…
- Conditions
- Lipedema, Pain, Activities of Daily Living, Musculoskeletal Ultrasound
- Trial name
- NCT06954870
- Testing
- Ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara Etlik City Hospital
Lipedema, Obesity, Morbid
Effect of an Low Carbon High Fat Diet on Pain- and Quality of Life in Patients With Lipedema
Lipedema is a chronic disease with unproportional, symmetrical fat accumulation in the lower extremities. Patients experience pain in affected areas, and reduced quality of life.
- Trial name
- LIPODIET (NCT03710798)
- Testing
- Low carbohydrate high fat diet
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Helse Nord-Trøndelag HF
Cardiovascular Diseases, Metabolic Disease
Vascular Lab Resource (VLR) Biorepository
This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases.
- Conditions
- Cardiovascular Diseases, Metabolic Disease, Peripheral Artery Disease, Carotid Disease
- Trial name
- NCT05628948
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- The Cleveland Clinic
Lipedema
Building Lipedema Research Resources
Lipedema is a disease marked by subcutaneous adipose tissue accumulation in the lower extremities of females that is accompanied by somatic pain and edema.
- Trial name
- BRR (NCT06180850)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Lipoedema
A Study to Evaluate the Clinical Benefit and Safety of Medical Compression Garments in the Management of Patients With Lipedema
Lipedema (LI) is a chronic condition, painful disease characterized by a disproportionate increase in adipose tissue and pain in women's legs and sometimes arms.
- Trial name
- LIP'EX (NCT07125092)
- Testing
- compression group
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Thuasne
Lipedema
The Effect of Systematic Endurance Training in Treatment of Women With Lipedema
Lipedema is a chronic adipose tissue disorder that primarily affects women. The etiology remains unclear and involves abnormal buildup of fat mainly in the lower limbs.
- Trial name
- LipidEx (NCT06558851)
- Testing
- High intensity endurance training
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- Norwegian University of Science and Technology
Lipedema
Aquatic Versus Land-Based Exercise in Women With Lipedema
To evaluate optimal workout environments, a 12-week study assigned women with moderate-to-severe lipedema to three distinct protocols: supervised pool workouts, equivalent land-based training, or basic standard monitoring.
- Trial name
- NCT07756463
- Testing
- aquatic therapy, land- based exercise, usual care
- Volunteers
- 60 people
- Sponsor
- Cairo University
Lipedema
Adipose Cellular Kinetics of Lipedema
Lipedema is characterized by an abnormal deposition of adipose tissue, resulting in fluid accumulation, limb enlargement, and pain. Lipedema is often misdiagnosed as simply obesity.
- Trial name
- LIPEDEMA (NCT05394467)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Pennington Biomedical Research Center
Lipedema
ESWT for Primary Lipedema
This randomized controlled clinical trial aims to evaluate the effectiveness of extracorporeal shockwave therapy (ESWT) when added to standard conservative treatment in women with primary lipedema.
- Trial name
- ESWT-LIP (NCT07240415)
- Testing
- Standard Conservative Therapy, radial ESWT
- Volunteers
- 50 people
- Sponsor
- Fatih Bagcier
Lipedema, Dercum Disease
Treatment of Women With Lipedema Involving Substantial Fat Knee of Women and Men With Nodular Dercum's Disease
This is an open label, 2 cohort, clinical trial in women with lipedema with substantial fat above the knee and men with Dercum's disease. Each cohort will have 6 subjects who will receive RZL-012.
- Trial name
- NCT03492840
- Testing
- RZL-012
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Raziel Therapeutics Ltd.