Clinical trials: Limb Edema
Lower Limb Lymphedema, Unilateral Leg Edema
Effects of Hydrotherapy on Unilateral Lower Extremity Lymphedema
Lymphedema is a chronic condition that negatively affects patients' quality of life and lower extremity functions, causing swelling and a feeling of heaviness in the extremity, as well as posing an economic burden.
- Trial name
- NCT06839885
- Testing
- Interventional group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Lower Limb Chronic Oedema
Oedema Study : Chroedem
The chroedem study is aiming to assess tissue and biomolecular components of chronic lower limb oedema (CO). The investigators working hypothesis is that according to the aetiology of CO, the proportion of oedema \& composition…
- Trial name
- CHROEDEM (NCT02914808)
- Testing
- Patients will undergo a lower limb MRI and blood tests
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer Female, Breast Cancer Lymphedema
The Effect of Arm Exercises on Arm Oedema After Breast Cancer Surgery
In order to prevent lymphedema after breast surgery, patients are advised to know the risk factors for lymphedema and to avoid situations that may cause lymphedema, to perform active and passive arm exercises, to evaluate the…
- Trial name
- NCT05303675
- Testing
- exercise and training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gulseren MARAS
Upper Limb Edema
Scapular PNF and Activity Oriented Antiedema Proprioceptive Therapy on Shoulder Dysfunction Post Mastectomy Lymphedema
Eighty -four female patients suffering from shoulder dysfunction after breast cancer-related arm lymphedema, will Cairo University hospitals be randomly distributed into three groups equal in number.
- Trial name
- NCT06602180
- Testing
- Scapular PNF technique, (TAPA) technique for the affected shoulder region plus conventional physiotherapy program in a form of (Complex decongestive therapy (CDT)., Activity-Oriented Antiedema Proprioceptive Therapy (TAPA) technique for the affected shoulder region plus conventional physiotherapy program in a form of (Complex decongestive therapy (CDT), Scapular proprioceptive neuromuscular facilitation PNF technique for the affected shoulder region plus conventional physiotherapy program in a form of (Complex decongestive therapy (CDT)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Leg Injuries, Fracture
Soft Part Management for Surgical Fractures of the Lower Limb
The assessment consists in comparing corticoids injection versus placebo in surgery of lower limb fractures The aim of study is to assess (state cutaneous, efficacy, safety) corticoids injection on a prospective, randomized…
- Conditions
- Leg Injuries, Fracture, Edema
- Trial name
- ICOMI (NCT03915223)
- Testing
- leg fracture
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Clermont-Ferrand
Edema Leg
Pneumatic Compression Versus Anti-thromboembolic Exercises for Patients Undergoing Total Hip Arthroplasty
This study is a randomized controlled trial, with two parallel arms. The open-label study will be conducted in accordance with the helsinky statement and good clinical practice standards.
- Trial name
- NCT05312060
- Testing
- PC Pneumatic compression, AE Antithromboembolic exercises
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Luca Marin
Pregnancy Complication
Title of the Research: Effect of Manual Lymphatic Drainage Massage Combined With Therapeutic Exercises On Lower Limbs Edema During Late Pregnancy
Objective of the study is to investigate the effect of adding manual lymphatic drainage massage to classical therapeutic exercises on resolving physiological lower limbs edema in late pregnancy women.
- Trial name
- NCT07761741
- Testing
- manual lymphatic drainage massage technique with specific therapeutic exercise
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Limb Volume, Measuring Edema
Measuring Volume Using a 3D Scanner and iPad to Grade the Swelling of Legs
We used a new and easy-to-measure iPad 3D scanner to measure swelling in lower limbs because current technology is not easily available or affordable.
- Trial name
- NCT06944041
- Testing
- STO3 sensor (Structure Inc., Boulder, CO)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The RANE Center for Venous and Lymphatic Diseases at St. Dominic's Hospital
Parkinson's Disease, Peripheral Edema
Domperidone as a Treatment for Dopamine Agonist-induced Peripheral Edema in Patients With Parkinson's Disease
The dopamine agonists, pramipexole (Mirapex) and ropinirole (Requip), are drugs that are used to treat symptoms of Parkinson's disease.
- Trial name
- NCT00305331
- Testing
- Domperidone (drug)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University Health Network, Toronto
Anesthesia, ERAS
Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries
Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.
- Conditions
- Anesthesia, ERAS, Fluid Overload, Hypovolemia; Surgical Shock
- Trial name
- NCT06133257
- Testing
- Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index, standard fluid management
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Edema, Sepsis
Relation Between the Increase of Peripheral Edema by Fluid Therapy and the Decrease in Microcirculatory Vesseldensity
Can videomicroscopy of the sublingual microcirculation detect the increase in edema before peripheral edema will appear? By measuring the decrease in vesseldensity after strong positive fluid balances within septic patients…
- Trial name
- NCT02661269
- Testing
- Videomicroscopy of the sublingual microcirculation, Bio-impedance measurements.
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Frisius Medisch Centrum
Varicose Veins of Lower Limb, Varix
Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins
The study is aimed at assessing the dynamics of changes in biochemical markers of venous wall remodeling (type 1 plasminogen activation inhibitor (PAI-1), fibronectin (fibronectin, FN), vimentin (vimentin, VM), von Willebrand…
- Conditions
- Varicose Veins of Lower Limb, Varix, Vascular Diseases, Leg Edema
- Trial name
- NCT06367166
- Testing
- "Venarus®" (diosmin and hesperidin), Endovenous laser ablation (EVLA) with miniphlebectomy, Elastic compression
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ryazan State Medical University
Hypertension
Manidipine Versus Amlodipine in Patients With Hypertension
The purpose of this study is to evaluate the effect of a third-generation Calcium Channel Blocker (CCB), manidipine, compared with second-generation Calcium Channel Blocker (CCB), amlodipine, on the development of peripheral…
- Trial name
- NCT03106597
- Testing
- Manidipine 20mg, Amlodipine 10mg
- Where
- 3 sites in South Korea
- Volunteers
- 46 people
- Sponsor
- Korea University Guro Hospital
Lower Extremity Edema, Lower Extremity Edema Chronic
Pedal Pump Clinical Trial on Edema V2
Previous research on the osteopathic manual technique entitled "Pedal Pump" has shown health benefits, specifically increasing lymphatic flow, decreasing lower extremity edema, and decreasing serum lactic acid after maximal…
- Conditions
- Lower Extremity Edema, Lower Extremity Edema Chronic, CHF - Congestive Heart Failure, CHF Exacerbation
- Trial name
- NCT07809516
- Testing
- Pedal Pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hillcrest
Upper Limb Edema, Critical Illness
Near-Infrared Light Devices Versus Landmark Approach for Peripheral Venous Access in Intensive Care Unit
The central venous catheter (CVC) is commonly used in intensive care unit (ICU). The primary complications associated with CVCs especially with prolonged use include thrombosis and infections.
- Trial name
- NCT06234293
- Testing
- near-infrared light device
- Where
- 4 sites in France
- Volunteers
- 380 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Chronic Edema, Lymphedema
Boosted Compression for Lower Limb Chronic Edema
Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care…
- Trial name
- BECOME (NCT07708662)
- Testing
- Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy
- Where
- 4 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Universiteit Antwerpen
Fluid Overload
Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs
Impact of intraoperative use of pneumatic peristaltic compression device on hemodynamics vis a vis on fluid requirement during general anaesthesia and surgery.
- Trial name
- NCT03789474
- Testing
- HUNTLEIGH FLOWTRON ACS900
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Rishikesh