Clinical trials: Lifestyle
NASH - Nonalcoholic Steatohepatitis
Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis
Participants meeting study entry criteria are randomized with equal probability to one of two study groups: (1) Lifestyle modification or (2) Vertical Sleeve Gastrectomy (VSG) with Iifestyle modification, followed for 12 months.
- Trial name
- NCT03587831
- Testing
- Vertical Sleeve Gastrectomy, Lifestyle Modification Counseling
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Overweight and Obese Adults, Obese Patients (BMI ≥ 30 kg/m²)
Eatit's Obesity Intervention: Effects on Weight, Eating Habits and Health
Obesity is a growing public health problem in Sweden, but access to care varies depending on geographical location. Eatit´s multimodal digitally dietitian-supported lifestyle intervention offers an accessible treatment…
- Trial name
- NCT07183228
- Testing
- Lifestyle Intervention for Obesity
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Eatit AB
Type 2 Diabetes, Obesity
Long-term Effects of Lifestyle Intervention During Pregnancy in High Risk Women and in Their Offspring - Role of Environmental, Genetic and Epigenetic Factors
SUBJECTS: All participants in the RADIEL-study (2008-2011) who delivered (n=535), will be invited to this follow-up study, with their children (age 3-5 years) and the father.
- Conditions
- Type 2 Diabetes, Obesity, Metabolic Syndrome
- Trial name
- NCT02048839
- Where
- Finland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Obesity Prevention, Obesity
Molecular Landscape of Complex Lifestyle Modification
The goal of this clinical trial is to detect the impact of the 3-month complex lifestyle intervention, consisting of dietary counselling, supervised exercise training and cognitive-behavioural intervention in middle-aged…
- Conditions
- Obesity Prevention, Obesity, Metabolic Disease
- Trial name
- COPMose (NCT06954298)
- Testing
- supervised lifestyle modification
- Where
- Slovakia
- Volunteers
- 50 people
- Sponsor
- Slovak Academy of Sciences
Obesity
Lifestyle Intervention Trial in Obese Elderly
Obesity causes frailty in obese older adults by exacerbating the age-related decline in physical function. However, appropriate management of obesity in older adults is controversial.
- Trial name
- LITOE (NCT01065636)
- Testing
- Diet + Resistance Training, Diet + Aerobic Training, Diet + Resistance/Aerobic Exercise
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Biomedical Research Institute of New Mexico
Sedentary Lifestyle, Hyperinsulinemia
Developing a Physiological Understanding of High Duration Activity
When muscles are not contracting, the local energy demand by muscle and use of specific fuels used to produce energy by oxidative metabolism are minimal.
- Conditions
- Sedentary Lifestyle, Hyperinsulinemia, Glucose Tolerance Impaired, Low-density-lipoprotein-type
- Trial name
- NCT05135234
- Testing
- Muscular Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
Non-Alcoholic Fatty Liver Disease, Obese
Fatty Liver in Obesity: Long-lifestyle Follow-up (FLiO)
Non-alcoholic fatty liver disease (NAFLD) is a condition of excessive hepatic lipid accumulation in subjects that consume less than 20g ethanol per day, without other known causes as drugs consumption or toxins exposure.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obese, Overweight
- Trial name
- FLiO (NCT03183193)
- Testing
- Control diet, FLiO diet
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Depression
Stepped Care Model of Lifestyle-based Mental Health Care for Depression
This study is a two-arm parallel randomised controlled trial comprising both outcome and cost-effectiveness analyses. A total of 244 eligible participants experiencing depressive symptoms will be randomly assigned to either the…
- Trial name
- NCT06825507
- Testing
- Lifestyle-based mental health care, Care-as-usual
- Volunteers
- 244 people
- Sponsor
- Chinese University of Hong Kong
Heart Failure, Metabolic Disease
Metabolic Abnormalities, Lifestyle and Diet Pattern in Heart Failure
Metabolic abnormalities (e.g., hypertension, diabetes mellitus, dyslipidemia, and obesity) and unhealthy lifestyle behaviors (e.g., smoking and drinking habits, sedentary behavior, sleep disorder and physical inactivity) and…
- Trial name
- MALD-HF (NCT03951311)
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Ruijin Hospital
Well-Being, Lifestyle, Healthy
An Exploratory Feasibility Study
This study explores the feasibility of ContextWell, a well-being education programme that combines an online webinar with an AI-powered behavioural nudging system.
- Conditions
- Well-Being, Lifestyle, Healthy, Young Adult, Behavior and Behavior Mechanisms
- Trial name
- Contextwell (NCT07009964)
- Testing
- ContextWell Educational Programme
- Where
- Ireland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Diabetes Mellitus, Type 2, Myocardial Infarction
Effect of Patient Education on Healthy Lifestyle Behaviors and Diabetes Self-management in Diabetics
The purpose of this study is to determine the effect of planned education given to individuals with diabetes mellitus who had myocardial infarction on healthy lifestyle behaviors and diabetes self-management.
- Trial name
- NCT05954819
- Testing
- Planned patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Istanbul University - Cerrahpasa
Obesity, Overweight
Examining the Feasibility of Collaborative Care Treatment for Overweight Adolescents
This project will examine the effectiveness of a primary care based intervention to help overweight teen girls adopt healthy lifestyle practices.
- Trial name
- SHINE-Garfield (NCT00462267)
- Testing
- Enriched lifestyle intervention
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Child, Overweight
Active Games: Increasing the Attractiveness of Active Video Game Play for Youth
The purpose of this study is to look at the effects of active video game play on youth physical activity.
- Conditions
- Child, Overweight, Sedentary Lifestyle
- Trial name
- NCT02940431
- Testing
- High Autonomy, Low Autonomy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Osteoporosis
Improving Bone Health in Adolescent Girls: The Youth Osteoporosis and Understanding Total Health (YOUTH) Study
Osteoporosis affects nearly half of all American women over age 50. During the teenage years, girls can increase bone growth to decrease their risk of osteoporosis later in life.
- Trial name
- NCT00067600
- Testing
- Diet with increased fruits, vegetables, and calcium, Increased high impact activity and resistance training
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cardiovascular Diseases (CVD)
Data Donation Model for Inclusive Cardiovascular Prevention Using the TRAIN Health Platform
Cardiovascular disease (CVD) is the leading cause of death in the Netherlands and worldwide. While prevention strategies have improved, many population groups, including women, individuals with a migration background, and people…
- Trial name
- DDM-TRAIN (NCT07238036)
- Testing
- Digital Lifestyle Feedback Module (optional)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Overweight and Obesity
An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents
The goal of this clinical trial is to learn about cardiovascular disease risk among adolescent girls with overweight/obesity. The main questions this trial aims to answer are: 1.
- Trial name
- NCT06147973
- Testing
- Acceptance-based Treatment (ABT), Health Education (HE) Comparison
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Obesity
Weight Loss and Reversing T2D Through eHealth Coaching
Background: Systematic reviews conclude that Internet and mobile interventions can significantly change lifestyle in a short time span.
- Trial name
- LIVA (NCT03788915)
- Testing
- Online dietetic lifestyle counseling, Usual care
- Where
- 2 sites in Denmark
- Volunteers
- 340 people
- Sponsor
- University of Southern Denmark
Healthy Lifestyle
¡Vivir Mi Vida! Pilot Study
Rationale: By the year 2050, the number of older adults in the US will more than double. Because older adults are more likely to develop chronic conditions such as cardiovascular disease and arthritis, society is facing a…
- Trial name
- NCT04623489
- Testing
- ¡Vivir Mi Vida! Lifestyle Intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Mb Crohn, Ulcerative Colitis (UC)
Uneven Nutrition and Life Style as IBD Triggers in Adolescents and Adults
The aims of the study are 1. to determine the effect on dysbiosis, permeability and inflammatory activity after administration of a Mediterranean like diet (a Nordic equivalent, "Nordiet"), 2.
- Trial name
- UNITA (NCT07389161)
- Testing
- Nordiet
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Region Skane
Morbid Obesity
Lifestyle vs.Surgery for Morbid Obesity Treatment
The purpose of the current study is to determine whether an intensive lifestyle intervention was as effective as surgery to treat morbid obesity nine years post-intervention.
- Trial name
- NCT02122029
- Testing
- Lifestyle counselling, Bariatric Surgery
- Where
- Greece
- Volunteers
- 29 people
- Sponsor
- Harokopio University
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