Clinical trials: Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation
- Condition Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation
- Accepts healthy volunteers yes
Neurodegenerative Diseases, Leukodystrophy
Home Exercise for Individuals With Neurodegenerative Disease
The primary goal of this study is to address the need for targeted therapeutic interventions for impairments that impact walking in related neurodegenerative diseases.
- Conditions
- Neurodegenerative Diseases, Leukodystrophy, Ataxia, LBSL
- Trial name
- NCT05443906
- Testing
- Home exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
LBSL, Leukoencephalopathies
Quantifying Disease Progression in LBSL
Leukoencephalopathy with brain stem involvement and lactate elevation (LBSL) is a genetic disorder caused by biallelic mutations in the DARS2 gene that encodes mitochondrial aspartyl tRNA synthase.(1, 2) It is characterized by…
- Trial name
- LBSL (NCT05750979)
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- M. Engelen