Clinical trials: Laryngoscopy, open to volunteers
Respiratory Distress Syndrome (Neonatal), Respiratory Distress Syndrome (RDS)
A Prospective Observational Study of Video Laryngoscopy Versus Direct Laryngoscopy for Insertion of a Thin Endotracheal Catheter for Surfactant Administration in Newborn Infants
Many premature babies have breathing difficulty after birth and receive help with a breathing machine (nasal continuous positive airway pressure, NCPAP).
- Conditions
- Respiratory Distress Syndrome (Neonatal), Respiratory Distress Syndrome (RDS), Video Laryngoscopy, Surfactant
- Trial name
- NEU-VODEtec (NCT06758492)
- Testing
- Video laryngoscopy used to insert thin endotracheal catheter, Direct laryngoscopy used to insert thin endotracheal catheter
- Where
- 16 sites in Croatia, Czechia and 7 more
- Volunteers
- 600 people
- Sponsor
- University College Dublin
Vocal Cord Disease, Vocal Cord Polyp
Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery
Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery.
- Conditions
- Vocal Cord Disease, Vocal Cord Polyp, Vocal Cord Cyst
- Trial name
- NCT06734975
- Testing
- Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Rutgers, The State University of New Jersey
Time, Dexmedetomidine
Do Increasing Preoperative Timing of Single Dexmedetomidine Dose Have an Effect on Stress Response of Laryngoscopy and Intubation?
This study aims to evaluate the effect of increasing preoperative timing of single dexmedetomidine on the stress response of laryngoscopy and intubation.
- Conditions
- Time, Dexmedetomidine, Stress Response, Laryngoscopy
- Trial name
- NCT07165483
- Testing
- Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Tanta University
Intubation, Intubation Complications
A Stepped Wedge Cluster Randomised Trial Of Video Versus Direct Laryngoscopy For Intubation Of Newborn Infants
Many newborn babies have difficulty breathing. When babies need a lot of help, a doctor will intubate them - i.e. put a tube into their windpipe (trachea) - so that they can be given support with a breathing machine.
- Conditions
- Intubation, Intubation Complications, Infant, Newborn, Infant Respiratory Distress Syndrome
- Trial name
- NEU-VODE (NCT06757543)
- Testing
- Video laryngoscopy, Direct laryngoscopy with standard laryngoscope
- Where
- 17 sites in Croatia, Czechia and 8 more
- Volunteers
- 840 people
- Sponsor
- University College Dublin
Evaluate Effect of Nebulized Dexmedetomedine Upon Blunting Autonomic Response of Laryngoscopy and Intubation in Patients Undergoing Elective Intubation
To Evaluate Effect of Nebulized Dexmedetomedine Upon Blunting Autonomic Response of Laeyngoscopy and Intubation in Patients Undergoing Elective Intubation
Laryngoscopy and intubation are painful stimuli ,that results in adverse physiological outcomes,like tachycrdia ,hypertension,arrythmiaa,pulmonary edema.
- Trial name
- NCT07480304
- Testing
- Nebulization of dexmedetomedine in group D, Nebulizition with normal saline in group C,after taking informed consent patients in group cwill be nebulized with 5 ml of normal saline 30 min prior to elective intubation ,HR,SBP,DBP,MAP monitored.
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Laryngoscopy, Hemodynamic Changes
Effect of Nalbuphine Versus Fentanyl on Hemdoynamic Effects of Laryngoscopy
Participants will undergo routine pre-operative evaluation. An intravenous line will be placed in the recovery area. On arrival in the operating room, standard monitoring (blood pressure, heart rate, oxygen saturation, ECG…
- Trial name
- NCT07435337
- Testing
- Nalbuphine, Fentanyl
- Where
- Pakistan
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Institute of Cardiology
Laryngoscopic Stress Response, Dexmedetomidine
Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial
After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication.
- Conditions
- Laryngoscopic Stress Response, Dexmedetomidine, Lignocaine
- Trial name
- NCT07611890
- Testing
- IV dexmedetomidine, IV Lignocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Rawalpindi Institute of Cardiology
Correlation of Difficult Airway Markers With Ultrasonographic Measurements in Obese Patients
Comparison of Airway Ultrasonography and Laryngoscopy Methods in Obese Patients
The main objective of this study was to examine the relationship between classical markers used in assessing difficult airway management in obese patients (Mallampati score, thyromental distance, sternomental distance, neck…
- Trial name
- NCT07482436
- Testing
- Airway ultrasonography, Macintosh Laryngoscope Intubation, Tuoren Videolaryngoscope Intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Difficult Airway, Obesity Difficult Airway Airway Management
Effect Of Left Head Rotation On Glottic View During Video Laryngoscopy In Obese Adults
This study aims to evaluate whether the Left Head Rotation (LeHeR) maneuver improves visualization of the vocal cords during video laryngoscopy in obese adult patients undergoing general anesthesia.
- Trial name
- LeHeR (NCT07590739)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Hospital, Oman
Airway Assessment, Laryngoscopy
Correlation of Neck Dimensions of Airway Evaluation
The goal of this observational study is to evaluate thyromental distance (TMD) and mandibular triangle perpendicular length (MTPL); to know which correlates better with the incisor vallecula distance (IVD).
- Trial name
- NCT07668297
- Where
- India
- Volunteers
- 240 people
- Sponsor
- Sir Ganga Ram Hospital
One Lung Ventilation, Intubation Complication
Videolaryngoscopy vs Direct Laryngoscopy for Double Lumen Tube Lumen Tube Placement - A Multicentre Randomized-controlled Trial (VOLCANO Study)
The general aim of the study is to observe whether the use of the Mc Grath™ videolaryngoscope instead of direct laryngoscopy can represent, as in the case of the single-lumen tube, an added value in the placement of the…
- Trial name
- VOLCANO (NCT06466759)
- Testing
- Mc Grath Videolaryngoscope
- Volunteers
- 750 people
- Sponsor
- Luca Brazzi
Airway Management
Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)
This study aims to investigate the optimal oxygen flow rate needed during tracheal intubation with the C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany) using Miller-blade or Macintosh-blade size No. 0 or No.
- Trial name
- OPTIMISE-2 (NCT05967507)
- Testing
- Low-flow nasal supplemental oxygen with a conventional nasal cannula during tracheal intubation with the C-MAC video laryngoscope, High-flow nasal supplemental oxygen (Fisher & Paykel, Auckland, New Zealand) during tracheal intubation with the C-MAC video laryngoscope
- Where
- 11 sites in United States, Australia and 5 more
- Volunteers
- 1,192 people
- Sponsor
- Thomas Riva
Post-Induction Hypotension
Prediction of Post-Induction Hypotension Using Plethysmographic Variability Index During Diagnostic Laryngoscopy
This prospective observational study aims to evaluate whether non-invasive hemodynamic parameters, including the plethysmographic variability index (PVI) and perfusion index (PI), can predict post-induction hypotension in…
- Trial name
- NCT07458893
- Testing
- Plethysmographic Variability Index (PVI) and Perfusion Index (PI) Monitoring
- Volunteers
- 110 people
- Sponsor
- University of Gaziantep
Laryngoscopy, Child
Correlation Between Sedation Depth Monitoring and Reflexes During Intravenous Anesthesia With Dexmedetomidine and Remifentanil in Children Undergoing Direct Laryngoscopy for Surgical Procedures
This study evaluates the correlation between sedation depth monitoring obtained by NeuroSENSE ® NS 701 Monitor and reflexes during intravenous anesthesia in children undergoing direct laryngoscopy for surgical procedures.
- Conditions
- Laryngoscopy, Child, Monitoring
- Trial name
- NCT03426579
- Testing
- NeuroSENSE ®in children
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Antwerp
Ultrasonographic, Mallampati Score
Combined Ultrasonographic Skin-to-Epiglottis Distance With Modified Mallampati Versus Modified Mallampati Score Alone in Predicting Difficult Laryngoscopy During Tracheal Intubation Under General Anesthesia
This study will evaluate how well an ultrasound measurement of the distance from the skin to the epiglottis, when combined with the modified Mallampati score, can predict difficult laryngoscopy in adult patients undergoing…
- Conditions
- Ultrasonographic, Mallampati Score, Mallampati Score, Difficult Intubation, Videolaryngoscope, Tracheal Intubation
- Trial name
- NCT07315256
- Testing
- Ultrasound-Guided Skin-to-Epiglottis Distance Measurement, Clinical Airway Assessment With Modified Mallampati Score
- Volunteers
- 160 people
- Sponsor
- Assiut University
Airway Complication of Anesthesia
Airway US in Predicting Difficult Pediatric Laryngoscopy
The hypothesis of this study is that ultrasound measurements may improve the preoperative detection of difficult laryngoscopy (DL) in pediatrics.
- Trial name
- AirwayUS (NCT06892405)
- Testing
- SonoSite™ S Series ultrasound
- Where
- Egypt
- Volunteers
- 49 people
- Sponsor
- Assiut University
Pediatric Anesthesia, Difficult Laryngoscopy
Preoperative Prediction of Difficult Airway in Children
This prospective observational study aims to evaluate the predictive value of preoperative clinical airway assessment parameters for difficult airway management in pediatric patients undergoing elective surgery under general…
- Trial name
- NCT07384611
- Testing
- Preoperative Clinical Airway Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Respiratory Distress Syndrome (Neonatal), Surfactant Deficiency Syndrome Neonatal
Video vs. Direct Laryngoscopy for Less Invasive Surfactant Administration
Many preterm babies born between 22-28+6 weeks' estimated gestational age (EGA) need surfactant, a medicine that helps the lungs.
- Trial name
- VID LISA (NCT07426016)
- Testing
- Video Laryngoscopy, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas Southwestern Medical Center
Airway Ultrasound Indices, Clinical Airway Assessment
Airway Ultrasound Indices for Prediction of Difficult Laryngoscopy in Pediatric Patients
The goal of this observational study is to compare the airway ultrasound indices and the preoperative clinical airway assessment concerning the difficult laryngoscopic view in paediatric patients undergoing elective surgery under…
- Trial name
- NCT07185516
- Testing
- Airway ultrasound indices, Clinical airway assessment
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgery
Diagnosis and Treatment of Foreign Bodies Outside Pharynx and Esophagus Lumen
Objective: To improve the success rate of the treatment of migrating foreign bodies in the upper aerodigestive tract. Methods: The medical records of inpatients conforming to the diagnosis of migrating foreign bodies between 2020…
- Trial name
- NCT04917367
- Testing
- exploratory surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine