Clinical trials: Laparoscopic Surgery, open to volunteers
Laparoscopic Obstetric Surgery
Total Intravenous Anesthesia (TIVA) Versus Inhalational Anesthesia at The End of Laparoscopic Obstetric Surgery Regarding Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) remain among the most common and distressing complications after general anaesthesia, with important consequences for patient comfort, satisfaction, recovery trajectories, and length of…
- Trial name
- NCT07270289
- Testing
- inhalational anaesthesia, total intravenous anesthesia (TIVA)
- Volunteers
- 98 people
- Sponsor
- Assiut University
Laparoscopic Colorectal Cancer Surgery
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Colorectal Cancer Surgery
Colorectal cancer is the second most common tumor in women and the third most common tumor in men, accounting for approximately 10% of tumors diagnosed and tumor-related deaths worldwide each year.
- Trial name
- NCT06636864
- Testing
- Intrathecal morphine, Intrathecal saline injection, TAPB
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Liver Surgery, Pulmonary Complications
Prevention of Pulmonary Complications After Laparoscopic Liver Surgery
Background: Postoperative pulmonary complications (PPCs) are the most common complications after major upper abdominal surgery. PPCs include respiratory infections, severe atelectasis, pleural effusion, bronchospasm, aspiration…
- Conditions
- Liver Surgery, Pulmonary Complications, Laparoscopic Liver Surgery
- Trial name
- PREPULCION (NCT07192575)
- Testing
- Perioperative Pulmonary Physiotherapy in Laparoscopic Liver Surgery
- Where
- 5 sites in Finland, Sweden
- Volunteers
- 364 people
- Sponsor
- Oulu University Hospital
Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy
Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Prostate cancer ranks second among all malignances in men and has become a significant threat to men's health. Robot-assisted laparoscopic radical prostatectomy (RARP) has become a standard treatment for prostate cancer.
- Conditions
- Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy, Enhanced Recovery After Surgery (ERAS) Protocol, Prehabilitation
- Trial name
- NCT05576766
- Testing
- Routine care, ERAS management pathway
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Peking University First Hospital
Surgery, Laparoscopic
Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain
This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery.
- Conditions
- Surgery, Laparoscopic, Laparoscopy, Penumoperitoneum
- Trial name
- NCT06504277
- Testing
- Low Pressure Penumoperitoneum, Standard Pressure Group (No intervention- active comparator)
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Robotic Surgical Procedures, Right Colon Tumors
Comparison of Short- and Long-term Outcomes Between Robotic and Laparoscopic Hemicolectomy of Right Colon Cancer : A Multicenter Propensity Score Matching Analysis
This is a retrospective, multicenter cohort study to compare short- and long-term outcomes between robotic and laparoscopic hemicolectomy of right colon cancer.
- Conditions
- Robotic Surgical Procedures, Right Colon Tumors, Cancer, Laparoscopic Abdominal Surgery
- Trial name
- NCT07029464
- Volunteers
- 4,000 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Laparoscopic Surgery, Neuromuscular Blocking Agents
Study of the Relationship Between Curarization and Pneumoperitoneum in Laparoscopic Surgery
The number of surgical procedures is increasing worldwide (1). Laparoscopic surgery is one of the surgical techniques that has become indispensable. Laparoscopic surgery is less invasive than laparotomy.
- Conditions
- Laparoscopic Surgery, Neuromuscular Blocking Agents, Pneumoperitoneum
- Trial name
- PneumandTOF (NCT07005518)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Gynecologic Laparoscopic Surgery, Regional Anesthesia Block
Transversus Abdominis Plane Block (TAP) Versus Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) in Laparoscopic Gynecologic Surgeries
Although laparoscopic techniques are considered minimally invasive surgical procedures with lower perioperative pain scores compared to open surgeries, they are still associated with significant levels of pain.
- Trial name
- NCT06995404
- Testing
- TAP Block Group, M-TAPA Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Ovarian Cysts, Laparoscopic Gynecologic Surgery
A Randomized Controlled Trial Study Comparing Adnexal Surgery by vNOTES or Laparoscopy
The aim with the study is to compare postoperative pain after vNOTES adnexal surgery versus laparoscopic adnexal surgery. Women aged 18 and above with an indication for adnexal surgery for benign gynecological pathology or…
- Conditions
- Ovarian Cysts, Laparoscopic Gynecologic Surgery, vNOTES
- Trial name
- ADNOLA (NCT06964594)
- Testing
- vNOTES adnexal surgery
- Volunteers
- 200 people
- Sponsor
- Region Skane
PCIA, Frailty
Impact of Frailty on Nalbuphine Dose for Postoperative Analgesia in Elderly Patients Undergoing Laparoscopic GI Surgery
This study aims to investigate the ED50 and ED95 of nalbuphine combined with dexmedetomidine in patient-controlled intravenous analgesia (PCIA) for elderly patients with different degrees of frailty, as well as their analgesic…
- Conditions
- PCIA, Frailty, Laparoscopic Gastrointestinal Surgery
- Trial name
- NCT06953570
- Volunteers
- 120 people
- Sponsor
- Yongtao Sun
Laparoscopic Surgery, Pneumoperitoneum
Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries
To compare the effects of Individualized positive end-expiratory pressure with recruitment maneuver on respiratory parameters and oxygenation in mechanical ventilation during laparoscopic surgeries with the fixed positive…
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Positive End Expiratory Pressure (PEEP)
- Trial name
- NCT06929078
- Testing
- Protective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Noor-Ul-Ain
Inguinal Hernia, Laparoscopic Surgery
Uterine Round Ligament Preservation Vs Resection in Laparoscopic Inguinal Hernia Repair in Women：A Multicenter,Stratified Randomized Controlled Trial
This study aims to compare the clinical effects of uterine round ligament preservation versus resection in laparoscopic inguinal hernia repair in women.The primary outcomes included Time required for patient surgery.The secondary…
- Conditions
- Inguinal Hernia, Laparoscopic Surgery, Randomized Controlled Trial
- Trial name
- NCT06885788
- Testing
- To remove the uterine uterine ligament
- Where
- China
- Volunteers
- 466 people
- Sponsor
- Nanchong Central Hospital
Artificial Intelligence (AI), Deep Learning
The Construction and Effect Verification of a Deep Learning-based Automated Semantic Segmentation Model for Medical Imaging
Hepatocellular Carcinoma(HCC) is a common disease in China, ranking as the fourth most prevalent malignant tumor and the third leading cause of cancer-related deaths in the country.
- Conditions
- Artificial Intelligence (AI), Deep Learning, Laparoscopic Surgery
- Trial name
- NCT06864702
- Testing
- Whether the patient received diagnosis and treatment at Zhujiang Hospital of Southern Medical University and retained medical images such as abdominal
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Laparoscopic Surgery, Positive End-Expiratory Pressure
Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients
Abdominal laparoscopy is widely utilized due to its benefits, including minimal invasiveness, improved cosmetic outcomes, and shorter hospital stays.
- Conditions
- Laparoscopic Surgery, Positive End-Expiratory Pressure, Electrical Impedance Tomography
- Trial name
- PEEP-EIT (NCT06850844)
- Testing
- electrical impedance tomography, Conventional Ventilation
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Laparoscopic Adnexal Surgery
Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery
We hypothesize that instilling intraperitoneal Marcaine (without epinephrine) at the end of a non-total laparoscopic gynecologic surgery (adnexa only, which includes the ovaries, fallopian tubes, and associated ligaments…
- Trial name
- NCT06842771
- Testing
- Normal Saline (0.9% NaCl), Marcaine hydrochloride without epinephrine 0.5%
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Tennessee
Laparoscopic Cholecystectomy Surgery
Beneficial Effects of Low-Dose Intravenous Dexmedetomidine Premedication in Patient Undergoing Laparoscopic Cholecystectomy Under General Anesthesia
Laparoscopic cholecystectomy (LC) is considered the standard treatment for gallbladder disease.1 Compared to open cholecystectomy, LC is the preferred treatment approach because it is associated with less surgical trauma, shorter…
- Trial name
- NCT06838650
- Testing
- Dexmedetomidine, Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Laparoscopic Surgery, Trendelenburg Position
Trend Correlation Between End-Tidal and Arterial Carbon Dioxide During Laparoscopic Surgery in Trendelenburg Position
In this study, we want to find out whether a person's "end-tidal carbon dioxide" (ETCO₂)-a value measured from the air they breathe out-accurately reflects the amount of carbon dioxide in their blood, called "arterial carbon…
- Trial name
- NCT06838078
- Volunteers
- 79 people
- Sponsor
- Koç University
Uterine Myoma, Surgery, Laparoscopic
Safety and Efficacy of Using a Novel Full Visual Access Platform System in Transvaginal Hysterectomy
The modified vNOTES hysterectomy was accomplished and validated for efficacy and safety using a multi-access vaginal confinement instrument with a fully visualised vaginal access platform.
- Trial name
- NCT06658145
- Testing
- Vnotes surgery using fully visualised surgical instruments, Vnotes surgery using traditional surgical instruments
- Where
- China
- Volunteers
- 94 people
- Sponsor
- China-Japan Friendship Hospital
Laparoscopic Surgery
A Comparative Study of Ventilation Strategies in Different Surgical Positions on Intracranial Pressure and Cerebral Blood Flow During Laparoscopic Surgery
The purpose of this clinical trial is to investigate the effects of laparoscopic surgery in the Trendelenburg and Reverse Trendelenburg positions, and variable tidal volume ventilation (V-VCV), pressure-regulated…
- Trial name
- NCT06805747
- Testing
- Variable tidal volume ventilation (V-VCV), Pressure-regulated volume-controlled ventilation (PRVC), Conventional volume-controlled ventilation (C-VCV)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Inner Mongolia Baogang Hospital
Laparoscopic Abdominal Surgery
Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery
This clinical trial aims to investigate the impact of multimodal analgesia regimens on postoperative pain management and gastrointestinal function recovery following laparoscopic abdominal surgery.
- Trial name
- NCT06772545
- Testing
- Epidural Analgesia, Paravertebral Block, Transversus Abdominis Plane Block
- Volunteers
- 120 people
- Sponsor
- Xiaguang Duan