Clinical trials: Language
Head and Neck Cancer
Towards A Better Paradigm for Head and Neck Cancer Treatment Applying Artificial Intelligence. HNC-TACTIC.
This will be an international, multicenter, retrospective, observational, and data-driven study using secondary data captured in EHRs.
- Trial name
- HNC-TACTIC (NCT05117775)
- Testing
- No intervention - Just description and predictive models
- Where
- Spain
- Volunteers
- 10,000 people
- Sponsor
- Savana Research
Stroke, Aphasia
Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment.
- Conditions
- Stroke, Aphasia, Reading Disorder
- Trial name
- NCT06213272
- Testing
- Phono-Motor Therapy, Aerobic Exercise Training (AET), Stretching
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Kessler Foundation
Stuttering
Genetic Factors Related to Stuttering
Stuttering is an abnormality in speech that affects the rhythm of speech. People who stutter know what they wish to say, but at the time are unable to say it because of involuntary repetition, unnecessary lengthening…
- Trial name
- NCT00001602
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Primary Progressive Aphasia, Frontotemporal Dementia
Long-term Effect of TMS in Primary Progressive Aphasia
There are very few treatments for neurodegenerative disorders, and the efficacy of these treatments is generally modest. Recent studies have shown a short-term positive effect of non-invasive neuromodulation techniques such as…
- Conditions
- Primary Progressive Aphasia, Frontotemporal Dementia, Alzheimer Disease
- Trial name
- RECONNECT (NCT05842473)
- Testing
- Transcranial Magnetic Stimulation (active), Language therapy
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Hospital San Carlos, Madrid
Autism Spectrum Disorder
Intervention for Toddlers at Risk for Autism Spectrum Disorders (ASD)
This research is being done to test the effectiveness of an early intervention model for very young children at high risk for autism spectrum disorders (ASD) and their families.
- Trial name
- NCT01179841
- Testing
- Playgroup, Parent Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cancer, Shared Decision Making
Use of and Attitudes Towards Large Language Models for Health Information Among People With Cancer, the Public, and Health-care Professionals
This cross-sectional survey examined how people with cancer, the general public and health-care professionals use large language models (LLMs) such as ChatGPT for health information, what they expect from them, how comfortable…
- Conditions
- Cancer, Shared Decision Making, Artificial Intelligence
- Trial name
- NCT07526441
- Where
- Germany
- Volunteers
- 6,632 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Reading Disability
Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults
The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and…
- Trial name
- NCT05523505
- Testing
- RLN real non-invasive brain stimulation intervention, RLN and CCN real non-invasive brain stimulation intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Speech Sound Disorder
BiOfeedback, Online for Sibilant Treatment
The goal of this clinical trial is to evaluate the efficacy of sibilant biofeedback treatment delivered via telepractice in six children ages 8:0-17;11 who present with distortions of /s/.
- Trial name
- BOOST (NCT07041723)
- Testing
- Visual-acoustic biofeedback for Sibilants
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Montclair State University
Smoking Cessation, Tobacco Dependence
Smoking-cessation: A Spanish-Language Clinical Trial
The purpose of this study is to develop and test a series of culturally relevant and appropriate booklets in Spanish, designed to assist Hispanic smokers in quitting smoking and remaining smoke-free.
- Trial name
- NCT02611076
- Testing
- Stop Smoking for Good Intervention in Spanish (SS-SP), Usual care (UC)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
AVM - Cerebral Arteriovenous Malformation, Language
Mechanism of Aphasia and Recovery of Language After the Injury of Geschwind's Territory: a Study Based on the Brain Network Analysis
At present, functional imaging studies have suggested that the Geschwind's territory (the inferior parietal lobe) is an important language area. It is the hub for semantics and phonetic language processing.
- Trial name
- NCT04295980
- Testing
- Surgical removal of the BAVMs
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Medical History Taking, Artificial Intelligence in Clinical Workflow
Augmenting Clinical Workflow With a Structured Chatbot for Patient History Collection and Diagnostic Support
Doctors spend much of each visit collecting the patient's medical history, and incomplete histories can delay diagnosis. This study tests an AI chatbot that interviews patients before their appointment and produces a structured…
- Conditions
- Medical History Taking, Artificial Intelligence in Clinical Workflow, Outpatient Clinical Encounter
- Trial name
- CHAT-HX (NCT07860762)
- Testing
- AI-Based Structured History-Taking Chatbot
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Aphasia, Stroke
Telerehabilitation for Aphasia (TERRA)
Speech-language therapy is generally found to be helpful in the rehabilitation of aphasia. However, not all patients with aphasia have access to adequate treatment to maximize their recovery.
- Conditions
- Aphasia, Stroke, Stroke Rehabilitation
- Trial name
- TERRA (NCT04682223)
- Testing
- Semantically-focused therapy tasks, Phonologically-focused therapy tasks
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of South Carolina
Healthy, Speech Disorders
Development of Normative Ultrasound Databases of Tongue Surface Configuration
Our past ultrasound research has indicated a need for baseline normative tongue data against which to compare our disordered speech populations.
- Trial name
- NCT00001218
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Aphasia
Determining Learning Ability in People With Aphasia
Aphasia is an impairment in the expression or comprehension of language that results from stroke, traumatic brain injury or progressive neurological disease.
- Trial name
- NCT05119023
- Testing
- SRT Observational Learning, AGL Observational Learning, AGL Rule-based Learning
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- MGH Institute of Health Professions
Cerebral Palsy
Translation of the Cerebral Palsy Quality of Life Questionnaire in Local Languages of Pakistan.
Descriptive analytical study to translate the CP-QOL into local languages of Pakistan that are, Pashto, Urdu, Punjabi, Sindhi and Balochi languages.
- Trial name
- NCT04852159
- Where
- Pakistan
- Volunteers
- 525 people
- Sponsor
- Riphah International University
Major Depressive Disorder (MDD)
Evaluating Conversational Artificial Intelligence for Depression Management
The goal of this clinical trial is to evaluate how a conversational method of collecting medical history affects patients' perceptions and experiences compared to clinical care as usual.
- Trial name
- NCT07105397
- Testing
- Conversational AI system vs Usual Care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- George Mason University
Aphasia, Global, Stroke
tDCS and Speech Therapy to Improve Aphasia
To study the effect of combined tDCS plus speech therapy compared to sham-tDCS plus speech therapy in subacute stroke patients suffering from moderate or severe aphasia.
- Conditions
- Aphasia, Global, Stroke, Transcranial Direct Current Stimulation, Speech Therapy
- Trial name
- MP-LOGA (NCT02395874)
- Testing
- tDCS + speech therapy
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Medical Park AG
Child Development, Child Behavior
Achieving Sustained Early Child Development Impacts at Scale: A Test in Kenya
An estimated 43% of children under age 5 in low- and middle-income countries (LMICs) experience compromised development due to poverty, poor nutrition, and inadequate psychosocial stimulation.
- Conditions
- Child Development, Child Behavior, Language, Child
- Trial name
- NCT06140017
- Testing
- Msingi Bora responsive parenting and family wellbeing program
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Parkinson Disease, Dysarthria
Dysarthria Management for Minor Groups
This study develops and conduct a small-scale clinical trial study in which the linguistic and cultural diversity of the participants is considered.
- Trial name
- NCT06593860
- Testing
- Remote speech rehabilitation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Florida State University
Dysarthria, Huntington Disease
Characterization of the Profile of Dysarthria in Huntington's Disease, Using the Clinical Evaluation Battery of Dysarthria
Huntington's disease is a hereditary disease of rare autosomal dominant transmission, both neurodegenerative and neuro-psychiatric.
- Trial name
- Huntington (NCT03142217)
- Testing
- Study of dysarthria in patients with Huntington's disease
- Sponsor
- Centre Hospitalier Universitaire, Amiens