Clinical trials: Labour;Obstructed
Caesarean Sections, Augmentation With Oxytocin
The Labour Progression Study, a Cluster Randomised Trial on Labour Progression for First Time Mothers
The purpose of this study is to evaluate if the rate of emergency caesarean section can be reduced if adhering to a dynamic labour progression curve compared to a static progression curve for first time mothers without…
- Conditions
- Caesarean Sections, Augmentation With Oxytocin, Labour Dystocia
- Trial name
- LAPS (NCT02221427)
- Testing
- Dynamic progression curve, Static labour progression curve (F)
- Where
- Norway
- Volunteers
- 6,582 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Dystocia
Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation
Oxytocin is a medication that is often used to strengthen contractions to overcome delayed labor progress. The primary aim of this study is to determine whether receiving a higher dose of oxytocin lowers the chance of needing a…
- Trial name
- NCT02487797
- Testing
- Oxytocin, Sodium Chloride 0.9%
- Where
- United States
- Volunteers
- 1,003 people
- Sponsor
- Northwestern University
Uterine Atony
Exploration and Determination of Genomic Markers Predictive of Uterine Atony
The primary objective of this study is to determine whether there are markers in the tissue of atonic uteri, and in the patients' plasma that would help identify patients likely to suffer postpartum hemorrhage due to uterine…
- Trial name
- NCT03413917
- Testing
- Analysis of genomic markers in uterine atony
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Postpartum Hemorrhage, Cesarean Section Complications
Placental Removal Method And Uterine Massage On Preventing Postpartum Hemorrhage
Postpartum hemorrhage is the leading cause of maternal deaths in all over the world, especially in developing and underdeveloped countries. Medical and surgical methods exist for management of bleeding.
- Conditions
- Postpartum Hemorrhage, Cesarean Section Complications, Uterine Atony
- Trial name
- NCT06192836
- Testing
- Manual Removal 1, Manual Removal 2, Controlled Cord Traction 1
- Where
- Turkey (Türkiye)
- Volunteers
- 361 people
- Sponsor
- Busra Lekesiz
Labor (Obstetrics)--Complications, Labor; Dyscoordinate
Biomarkers of Uterine Muscle Physiology
This observational study characterizes the relationship between amniotic fluid lactate and uterine electromyography during labor in healthy individuals at term planning a vaginal birth.
- Trial name
- BUMP (NCT04251702)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prolonged Labor, Failed Induction
Oxytocin Rest to Reduce Cesarean Delivery
Prolonged labor is usually managed with continuous oxytocin infusion. "Oxytocin rest" has been proposed as a strategy to resolve protracted labor in patients who have received continuous oxytocin without progress.
- Conditions
- Prolonged Labor, Failed Induction, Labor Dystocia
- Trial name
- ORCA (NCT06268431)
- Testing
- Oxytocin rest
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Christiana Care Health Services
Prolonged Labor, Labor Dystocia
Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour
The goal of this clinical trial is to learn if oral bicarbonate can treat prolonged labour in nulliparous women with prolonged labour.
- Trial name
- ProLabour (NCT07321379)
- Testing
- Sodium bicarbonate
- Where
- 3 sites in Denmark
- Volunteers
- 1,520 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Humerus Fractures
Serum-Protein-Based Indices for the Progression of Fracture Healing and Nonunion
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific…
- Trial name
- UNION (NCT05143476)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Major Extremity Trauma Research Consortium
Labour Dystocia
Implementation of AFL Monitoring in Clinical Use
The overall objective of this randomized controlled trial is to develop a clinical standard procedure for measuring lactate in amniotic fluid (amniotic fluid lactate = = AFL) during childbirth before oxytocin stimulation is…
- Trial name
- NCT03650972
- Testing
- Samarin
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Postpartum Hemorrhage, Uterine Atony
ED90 Determination of Carbetocin for the Prevention of Uterine Atony in Women Undergoing an Elective Cesarean Delivery
The purpose of this trial is to determine the effective dose of carbetocin which would prevent the occurrence of postpartum uterine atony in 90% of women undergoing an elective cesarean delivery.
- Trial name
- NCT01579201
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Cesarean Section, Dystocia
The REDUCED Trial: REDucing the Utilization of CEsarean Sections for Dystocia
This project is a clustered randomized controlled trial of a knowledge translation intervention of new ACOG guidelines for the diagnosis of poor progress in labor.
- Trial name
- REDUCED (NCT02874443)
- Testing
- Knowledge Translation of labor management guidelines
- Where
- Canada
- Volunteers
- 88,918 people
- Sponsor
- University of Calgary
Dystocia; Fetal, Labor Long
Mouth Guard Use in the Second Stage of Labor
Shortening the second stage of labor, the time spent pushing the baby out, is important for positive mother and infant's outcomes.
- Conditions
- Dystocia; Fetal, Labor Long, Cesarean Section, Affecting Fetus or Newborn
- Trial name
- NCT03520530
- Testing
- Mouth Guard
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Dystocia
A Comparative Study of the Effect of Two Partographs on the Cesarean Section Rate in Women in Spontaneous Labour
In the 2010-french perinatal survey, the overall cesarean section (CS) rate during labour was 21 % and 16% to 38% in case of dystocia.
- Trial name
- PARTODYS (NCT02741141)
- Testing
- New partograph based on the studies of Neal and Lowe, Classical partograph
- Where
- France
- Volunteers
- 633 people
- Sponsor
- University Hospital, Strasbourg, France