Clinical trials: Labor Stage, First
HIV -1 Infection
Study of GS-0415 and How It Works in People With HIV
The goals of this clinical study are to learn more about the study drug GS-0415, safety, tolerability, and pharmacokinetics (PK) of single ascending doses (SAD) and multiple ascending doses (MAD) of subcutaneous (SC) and…
- Trial name
- NCT07719491
- Testing
- GS-0415
- Where
- 16 sites in United States
- Volunteers
- 112 people
- Sponsor
- Gilead Sciences
Labor, First Stage
Role of Hyoscine Bromide in Latent and Active Labor
The purpose of this study is to determine whether hyoscine bromide decreases the duration of the active phase of labor.
- Trial name
- NCT02103166
- Testing
- Hyoscine bromide, Physiological serum
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Labor Pain, Satisfaction
Focusing on Maryam's Flower at Labor
Objective: To determine the effect that focusing attention on the plant, Maryam's Flower, has on pregnant women's perception of pain, level of comfort and labor satisfaction during the first phase of labor.
- Trial name
- NCT04393870
- Testing
- Foccusing on Maryam's Flower
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2
Brief Summary: Until recently, at Mount Sinai Hospital, epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication…
- Trial name
- NCT02758405
- Testing
- Bupivacaine, Fentanyl, Infusion pump
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Bronchopulmonary Dysplasia
Follow-up Safety and Efficacy Evaluation on Subjects Who Completed PNEUMOSTEM® Phase-II Clinical Trial
This is a follow-up study to investigate the long-term safety and efficacy of PNEUMOSTEM® versus placebo, for the treatment of BPD in premature infants.
- Trial name
- NCT01897987
- Testing
- Pneumostem®, normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 62 people
- Sponsor
- Medipost Co Ltd.
Prolonged First Stage Labor - Prevention
Best Partograph Action Line to Prevent Prolonged Labour
Objective: To compare active labour outcomes in nulliparous women at term supervised with a partograph with the action line placed at either 2 hours or 4 hours and to determine whether the 2-hour action line placement is better…
- Trial name
- Partograph (NCT02911272)
- Testing
- 2-hour action line on WHO modified partograph, Oxytocin, Forewater amniotomy
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Benin
Cancers With HER2 Expression
A First in Human Study of BAY2701439 to Look at Safety, How the Body Absorbs, Distributes and Excretes the Drug, and How Well the Drug Works in Participants With Advanced Cancer Expressing the HER2 Protein
In this study, researchers want to learn about the safety of drug BAY2701439 and how well the drug works in patients with advanced cancer that has the protein HER2 (Human Epidermal growth factor Receptor 2) and cannot be cured by…
- Trial name
- NCT04147819
- Testing
- BAY2701439
- Where
- 6 sites in United States, United Kingdom
- Volunteers
- 14 people
- Sponsor
- Bayer
Transcutaneous Electric Nerve Stimulation, Labor Pain
Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) Versus Placebo During the First Stage of Labor
This study seeks to verify the analgesic efficacy of TENS during the first stage of labor applying TENS parameters that, according to with the evidence, can be effective for this application and discarding the placebo effect…
- Trial name
- NCT03990441
- Testing
- TENS
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Vaginal Delivery
Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women
A case control trial Patients who meet the inclusion criteria were asked to participate in the study and a written consent was obtained from each patient after explaining thoroughly the nature and the scope of the study.
- Trial name
- NCT03055390
- Testing
- hyoscine butylbromide
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor, First Stage, Labor, Second Stage
Effect of Dianatal Obstetric Gel (Cross-linked Polyacrylic Acid) on Outcomes in Vaginal Delivery
Perineal massage at the end of labor stage 2 has been investigated in 2 randomized controlled trials using a water soluble lubricant.
- Trial name
- NCT01546129
- Testing
- Dianatal Obstetric Gel (Cross-linked polyacrylic acid)
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Labor Pain
Effects of Ambulation During First Stage of Labour on Maternal and Neonatal Outcomes
This study investigates the effect of ambulation (walking) during first stage of labour on maternal and neonatal outcomes. In the intervention group women will be encouraged to ambulate and women in the control group will receive…
- Trial name
- NCT03447015
- Testing
- ambulation
- Where
- Jordan
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Mutah University
Hepatocellular Carcinoma
A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer
In this study, researchers want to learn about the safety of a new drug, BAY 3547926, and how well the drug works in people with a type of liver cancer called advanced hepatocellular carcinoma (HCC), which has a special protein…
- Trial name
- BANTAM-01 (NCT06764316)
- Testing
- BAY 3547926, BAY 3547922, BAY 3713391
- Where
- 36 sites in United States, Belgium and 7 more
- Volunteers
- 148 people
- Sponsor
- Bayer
Geographic Atrophy Secondary to Age-related Macular Degeneration
An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)
This is a clinical study to evaluate the safety, tolerability and efficacy of CTx001, administered via a single subretinal injection, for GA (secondary to AMD).
- Trial name
- Opti-GAIN (NCT07392255)
- Testing
- CTx001
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 75 people
- Sponsor
- Complement Therapeutics
Vaginal Delivery
Audit of Management of First Stage of Labour in Assiut University Hospitals : a Quality Improvement Project
auditing the current management of first stage of normal vaginal deliveries at Assiut university hospitals emergency obstetric care
- Trial name
- NCT05143944
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Parturition, Humanizing Deliver
Birth Ball Versus Meperidine and Haloperidol Injection for Pain Relief During First Stage of Labour
The study was performed at Gregorio Marañón Hospital birth centre. A Randomised Clinical Trial comparing the two methods of pain relief in the first time of labour was carried out.
- Conditions
- Parturition, Humanizing Deliver, Labor Pain, Natural Childbirth
- Trial name
- NCT02493192
- Testing
- pethidine and haloperidol injection, birth ball
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Diffuse Large B-Cell Lymphoma, B-Cell Malignancies
A Study Investigating the Safety and How the Trispecific T-Cell Engaging Antibody BG-T0050 Works in Adults With Diffuse Large B-cell Lymphoma (DLBCL) and Other Aggressive B-Cell Malignancies
The purpose of this study is to test the safety and tolerability of BG-T0050 and to identify the recommended dose and dosing schedule (including dose levels and timing) that can be taken without having serious side effects in…
- Trial name
- NCT07881211
- Testing
- BG-T0050
- Volunteers
- 70 people
- Sponsor
- BeOne Medicines
Pain, Labor, Satisfaction, Patient
The Effect of Birth Ball and Birth Dance Applied in the First Stage of Labor on Some Parameters
Aim: The study was conducted to investigate the effect of birth ball and birth dance practices applied in the first stage of labour on pain, mode of delivery, maternal satisfaction and duration of labour.
- Trial name
- NCT06085820
- Testing
- Experimental (birth ball), Experimental (birth dance)
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Amasya University
Labor Pain
The Effect of the Multifunctional Birthing Ball on Labor Pain
Objective: By using the newly designed multifunctional birthing ball, it is aimed to reduce the intense perineal and sacral pain in the first and second stages of labor, to prevent perineal tears, pain and episiotomy opening with…
- Trial name
- NCT06229808
- Testing
- Multifunctional Birthing ball
- Where
- Cyprus
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Childbirth, Aromatherapy
Comparison Of The Effects Of Swedish Massage With Natural Oils
Aim: This study aimed to evaluate the effects of Swedish massage combined with lavender and chamomile oils on childbirth outcomes during the first and second stages of labor.
- Conditions
- Childbirth, Aromatherapy, Pain Management, Fear
- Trial name
- Comparison (NCT07652957)
- Testing
- Aromatherapy and Massage Care for labor pain management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Labor Pain, Labor; Prolonged, Second Stage
Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous
Remifentanil may be an ideal drug for labor analgesia due to its pharmacodynamic and pharmacokinetic profile. As compared to epidural analgesia, it demonstrated satisfactory for pain relief at the beginning of labour with a…
- Conditions
- Labor Pain, Labor; Prolonged, Second Stage, Labor; Prolonged, First Stage
- Trial name
- NCT02963337
- Testing
- remifentanil, combined spinal-epidural analgesia
- Where
- Slovenia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana