Clinical trials: Labor Stage, First
Analgesia, Obstetrical
Hyoscine ButylBromide for Intrapartum Analgesia
The aim of this study is to assess whether hyoscine butylbromide is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02557087
- Testing
- Hyoscine, Pethidine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Labor Position and Maternal Birth Experience
Standing vs. Squatting Positions During Labor
Background: Maternal position during labor is a key non-pharmacological strategy that supports physiological birth and women's active participation in the childbirth process.
- Trial name
- NCT07383181
- Testing
- Standing Position During Labor, Squatting Position During Labor
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Biruni University
Heat Exposure, Labor Pain
Heat Application to the Sacral Region and Pain Level During the First Stage of Labor
The aim of this study was to determine the effect of hot application applied to the sacral region during first stage of labor on women's pain level and labor process.
- Conditions
- Heat Exposure, Labor Pain, Apgar Score, Duration of Labor
- Trial name
- NCT06297031
- Testing
- heat application
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Labor Onset and Length Abnormalities, 37 or More Completed Weeks of Gestation
Comparative Study Between Using WHO Labour Care Guide & Modified WHO Partograph
This randomized clinical trial is based on comparing the efficiency of modified WHO partographs vs. the new WHO labour care guide in monitoring and assessing the outcome of labour.
- Conditions
- Labor Onset and Length Abnormalities, 37 or More Completed Weeks of Gestation, First Birth
- Trial name
- NCT06537089
- Testing
- Supportive care measures, LCG guided labour interference
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hend Mahmoud Abdelghany
Obstetric Pain, Labor Pain
Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia
The purpose of this prospective randomized controlled study is to compare the number of physician top-up interventions during the first stage of labour between two different neuraxial analgesia techniques : the dural puncture…
- Conditions
- Obstetric Pain, Labor Pain, Anesthesia
- Trial name
- DPE (NCT04728048)
- Testing
- Dural puncture epidural, Standard epidural
- Where
- Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Analgesia, Obstetrical
Tenoxicam for Intrapartum Analgesia
The aim of this study is to assess whether tenoxicam is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02549118
- Testing
- Tenoxicam, Pethidine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Labor Stage, First
The Effect of Hyoscine Butyl Bromide on the First Stage of Labor in Term Pregnancies
To determine whether hyoscine butyl bromide is effective in shortening the first stage of labor, with no increase in maternal or neonatal complications.
- Trial name
- NCT00409890
- Testing
- Hyoscine Butyl Bromide
- Where
- Jamaica
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital of the West Indies
Labor Pain
The Effect of Su-jok Therapy Applied in the First Stage of Labor on Pain Level in Primiparas
The aim of this study is to examine the effect of sujok therapy applied in the first stage of labor on the pain level in primiparas.
- Trial name
- NCT06760013
- Testing
- Su Jok Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hitit University
Labor Pain, Anxiety
The Effect of Virtual Reality Glasses on Labor Pain
There are different medicinal and non medicinal methods to control labor pain. Today, much attention has been on non medicinal methods because of limitations and complications of medical procedures.
- Trial name
- NCT01687933
- Testing
- three-dimensional glasses(manufactor Vuzix,wrap 920), usual care
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Labor
Effect of Hyoscine- Bromide on Duration of the First Stage of Labor
Spasmolytic drugs are frequently used in delivery rooms to overcome cervical spasms and thus reduce the duration of labor. The aim of this randomized double blind placebo controlled trial is to study the efficacy of hyoscine…
- Trial name
- NCT06056869
- Testing
- hyoscine butylbromide, normal saline
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Neonatal Morbidity
Reducing Neonatal Morbidity by Discontinuing Oxytocin During the Active Phase of 1st Stage of Labor
The purpose of this study is to measure the impact of a discontinuous administration of oxytocin during the active phase of the 1st stage of labor on the neonatal morbidity rate.
- Trial name
- STOPOXY (NCT03991091)
- Testing
- discontinuation of oxytocin administration, continuation of oxytocin administration
- Where
- France
- Volunteers
- 2,459 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Labor
The Effect of Hyoscine Butylbromide on Shortening of First and Second Stages of Labor
The management of normal labor is both an art and a science. For decades, health providers have worked to manage labor actively and safely, with the goal of shortening the duration of painful labor.
- Trial name
- NCT02839213
- Testing
- Hyoscine Butyl bromide, Saline
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Woman's Health University Hospital, Egypt
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor: Comparing 125 mL/h Versus 250 mL/h Bolus Delivery Flow
At Mount Sinai Hospital, epidural analgesia for labor pain is delivered by programmed intermittent epidural bolus (PIEB), in combination with pushes of medication activated by the patient, a technique called patient controlled…
- Trial name
- NCT03236298
- Testing
- CADD-Solis Ambulatory Infusion System
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain
Bupivacaine, Levobupivacaine and Ropivacaine After Intrathecal and Extradural Injection in Labour
A need exists to define the best local anesthetic and technique for pain relief in early labour. We suggest that calculating the molar Median Effective Dose for bupivacaine, levobupivacaine and ropivacaine given both by the…
- Trial name
- NCT01201213
- Testing
- local anaesthetic injection
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- NHS Tayside
Melanoma, Clear-Cell Renal-Cell Carcinoma (ccRCC)
A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body
This study is researching an experimental drug called REGN10597 alone or in combination with another drug called cemiplimab (called "study drug(s)").
- Conditions
- Melanoma, Clear-Cell Renal-Cell Carcinoma (ccRCC), Advanced Solid Tumors
- Trial name
- BrILliance (NCT06413680)
- Testing
- REGN10597, Cemiplimab
- Where
- 11 sites in United States
- Volunteers
- 240 people
- Sponsor
- Regeneron Pharmaceuticals
Labor Pain, Nutrient Intake
The Effect of Nutrition and Fluid Intake in the First Stage of Labor
Birth is a process that requires large amounts of energy. As a result of skeletal and smooth muscle contractions at birth, the body's basal metabolic rate, energy requirement, hydration requirement, and insensible fluid loss are…
- Conditions
- Labor Pain, Nutrient Intake, Fluid Therapy
- Trial name
- NCT06547177
- Testing
- fruit juice
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hilal Yuvacı
Analgesia, Obstetrical
Paracetamol for Intrapartum Analgesia
The aim of this study is to assess whether paracetamol is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02578251
- Testing
- Paracetamol, Pethidine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Labor Pain
Labor Analgesia in the Latent Phrase
Painless labor is an essential part in woman's health care. Labor analgesia in the active phrase is in popular use currently. However, parturients are still haunted by the labor delivery pain in the latent phrase up to 7-8 hours…
- Trial name
- LALP (NCT00647725)
- Testing
- Active phrase epidural analgesia, Latent phrase epidural analgesia
- Where
- China
- Volunteers
- 15,000 people
- Sponsor
- Nanjing Medical University
Vaginal Delivery
Measurement of the Fetal Occiput-spine Angle During the First Stage of Labor as Predictor of the Outcome of Labor
2D trans abdominal ultrasound was done during the first stage of labor. If fetal position is occiput anterior and fetal presentation is vertex, two dimensional sagittal picture of the fetal head and upper spine was acquired and…
- Trial name
- NCT03264599
- Testing
- transabdominal ultrasound
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Cairo University
Preterm Birth
Labor Characteristics and Maternal-Infant Outcomes in Preterm Primiparous Women
This retrospective observational study evaluates labor characteristics in primiparous women with spontaneous preterm birth at different gestational ages and examines their associations with maternal and neonatal outcomes.
- Trial name
- NCT07844499
- Testing
- Gestational Age at Delivery
- Where
- China
- Volunteers
- 436 people
- Sponsor
- Maternal and Child Health Hospital, Jiading District