Clinical trials: Labor Analgesia
Neuraxial Analgesia, Labor Analgesia
Effect of Increased BMI on Efficacy of Labor Analgesia
This study seeks to identify the most effective neuraxial technique for labor analgesia in Class III parturient
- Trial name
- NCT07367347
- Testing
- Neuraxial analgesia
- Where
- Qatar
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Mariah Arif
Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor, Analgesia
Postoperative Analgesic Effect of Esketamine
The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after caesarean section.
- Trial name
- NCT05582135
- Testing
- 2 mg morphine sulfate, 0.25mg/kg esketamine, 0.25mg/kg of esketamine in combination with 2 mg morphine sulfate
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Xuanhan County People's Hospital
Fetal Bradycardia Complicating Labor and Delivery, Fetal Bradycardia During Labor
Oxytocin and Fetal Heart Rate Changes
The reported risk of nonreassuring fetal heart trace following neuraxial analgesia is 3-23%. This variability may be due to fluid and oxytocin management prior to and during the initiation of neuraxial analgesia.
- Conditions
- Fetal Bradycardia Complicating Labor and Delivery, Fetal Bradycardia During Labor, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus
- Trial name
- NCT03232918
- Testing
- Half dose Oxytocin
- Where
- 2 sites in United States
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Unyime Ituk
Labor Pain
Differential Sensory Block During Labor Epidural Analgesia: a Prospective Observational Study to Investigate the Relationship of Lower and Upper Sensory Block Levels to Cold With Sensory Block to Pinprick and Light Touch
Epidural analgesia remains the gold standard for pain control during labor and delivery. Proper assessment of an epidural's level of blockade is important for providing safe and effective analgesia.
- Trial name
- NCT05187962
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain, Obstetric Pain
Programmed Intermittent Epidural Bolus (PIEB) Techniques for Labour Analgesia
Epidural Analgesia remains the most effective form of pain relief in labour. After initiating epidural analgesia, there are many epidural drug regimens that can be employed to maintain analgesia for the duration of labour using…
- Conditions
- Labor Pain, Obstetric Pain, Analgesia
- Trial name
- PIEB (NCT06266767)
- Testing
- Levobupivacaine and Fentanyl
- Where
- Qatar
- Volunteers
- 136 people
- Sponsor
- Hamad Medical Corporation
Premature Birth
Impact of Complementary Medicine Techniques (Therapeutic Touch and Hypno Analgesia) on the Term of Delivery of Patients Hospitalized for Preterm Labor (Hypnorelax)
The threat of premature birth (MAP) is the leading cause of hospitalization during pregnancy complicated by preterm delivery in 5-10% of cases in developed countries.
- Trial name
- Hypnorelax (NCT02505100)
- Testing
- Touching relaxant, Hypnoses
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy Related
Dexmedetomidine-Ropivacine Versus Sufentanil-Ropivacaine for Epidural Labor Analgesia
Sufentanil-ropivacaine combination is commonly used for epidural labor anesthesia, but is associated with some adverse events. Dexmedetomidine is a high selective alpha2-adrenoceptor agonist.
- Trial name
- NCT05698407
- Testing
- Dexmedetomidine, Sufentanil
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Musculoskeletal Diseases, Work-Related Condition
Work-related MusculoSkeletal Disorders Questionnaire
Development and validation of a multi-factor and self-perceived risk assessment questionnaire, specifically referred to WMSDs-related pain and risk factors
- Trial name
- WMSD (NCT04192604)
- Testing
- WMSDsQ
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Neuroaxial Analgesia Procedures
EPIDURAL- Evaluation of Preexisting Information Regarding Neuroaxial Procedures for Labour Analgesia
The aim of this research project is to anonymously survey pregnant patients before the anaesthesiological consultation about their prior knowledge of planned neuroaxial procedures in the context of childbirth by conducting an…
- Trial name
- EPIDURAL (NCT06201936)
- Testing
- Preliminary information on neuroaxial procedures
- Where
- Germany
- Volunteers
- 1,346 people
- Sponsor
- Goethe University
Labor Pain, Post-cesarean Delivery
Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia
Pharmacogenetics has allowed clinicians to identify associations between an individual's genetic profile and his/her response to drugs.
- Trial name
- NCT00418015
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Analgesia, Obstetrical
Hyoscine ButylBromide for Intrapartum Analgesia
The aim of this study is to assess whether hyoscine butylbromide is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02557087
- Testing
- Hyoscine, Pethidine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Labor
Do Peanut Shaped Birthing Balls Reduce the Length of Labor in Patients With Epidural Analgesia?
Labor patients who meet inclusion and exclusion criteria will be consented to be participate in this study to determine if the use of a peanut shaped birthing ball reduces the length of labor and reduces the incidence of cesarean…
- Trial name
- NCT02539563
- Testing
- peanut shaped birthing ball
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Wake Forest University Health Sciences
Epidural Anesthesia in Labor and Delivery
The Effects of Epidural Analgesia on Maternal-Infant Bonding and Birth-Related Trauma
This prospective, single-center study aims to evaluate the effects of epidural analgesia on maternal-infant bonding and perceived birth-related trauma in women undergoing vaginal delivery.
- Trial name
- NCT07077785
- Testing
- Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University Research Hospital
Pregnancy, Breech Presentation
The Effect of Combined Spinal-Epidural Analgesia on the Success of External Cephalic Version (ECV) for Breech Position
We aim to answer the clinical question: Does combined spinal-epidural analgesia improve the success rate of external cephalic version? We hypothesize that neuraxial analgesia (spinal or epidural analgesia) during version for…
- Trial name
- Version (NCT00565383)
- Testing
- Combined spinal-epidural analgesia, Intravenous fentanyl (50mcg)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Northwestern University
Epidural Anesthesia in Labor and Delivery, Doppler Ultrasound
EPidural's Impact on Contractions and Fetal REsponse
This prospective observational study aims to assess the impact of epidural analgesia (ELA) on uterine contractility, cardiotocography (CTG) patterns, and maternal-fetal hemodynamics in term pregnancies.
- Conditions
- Epidural Anesthesia in Labor and Delivery, Doppler Ultrasound, Uterine Contraction
- Trial name
- EPI-CARE (NCT06860854)
- Testing
- Epidural Analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Pain
Sole Local Anesthetic Versus Opioid Plus Local Anesthesia in Epidural Labor Analgesia
It is common for obstetric anesthesia using opioid supplement to local anesthetics for epidural labor pain control. Given the low doses of these epidural drugs, we never doubt the necessity of the supplement of opioid to lacal…
- Trial name
- OLAA (NCT02036242)
- Testing
- Sole local anesthetic, Sufentanil (Opioid plus local anesthetic), Ropivacaine
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Labour Analgesia
Effect of Epidural Needle Injection on Catheter Placement Success During Painless Labour
Epidural analgesia is the gold standard for painless labour, but successful catheter placement can be technically challenging due to anatomical and physiological changes in pregnancy.
- Trial name
- NCT07327918
- Testing
- Injection Group, Control group
- Where
- Egypt
- Volunteers
- 216 people
- Sponsor
- Al-Azhar University
Labor, Analgesia, Epidural
Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia
Epidural chloroprocaine is often used in obstetrical anesthesia because of its fast onset and short duration. These properties make it an ideal drug to use for epidural anesthesia in patients undergoing postpartum tubal ligation.
- Trial name
- NCT00487084
- Testing
- Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Labor Pain
Does Ultrasound Scanning of the Lumbar Spine Improve Patient Satisfaction and the Ease of Insertion Epidurals?
Ultrasound scanning of the back has been shown to increase success when used to guide epidural catheter insertion. However, this technique is not applied widely in clinical practice.
- Trial name
- NCT00996905
- Testing
- Portable ultrasound machine
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain Relief
Comparison of Loss of Resistance Techniques
The purpose of this study is to determine whether there is a difference in success outcome of the combined spinal epidural labor analgesia between air versus saline when used to identify the epidural space.
- Trial name
- NCT00638274
- Testing
- Air, Saline
- Where
- United States
- Volunteers
- 356 people
- Sponsor
- Wake Forest University Health Sciences