Clinical trials: Labor
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Pulse Pressure and Post-epidural Fetal Heart Rate Changes
Epidural anesthesia, the most common method of pain control in labor, can contribute to alterations in maternal blood pressure and/or fetal heart rate changes.
- Trial name
- NCT02565485
- Testing
- Lactated Ringer's
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- MetroHealth Medical Center
Labor Pain
Best Beginnings for Babies Birth Sister Program Evaluation
Peer support during labor, birth and the perinatal period (also known as "doula" support) has been shown in some studies to reduce cesarean rates, postpartum depression and increase breastfeeding rates.
- Trial name
- BBB (NCT02550730)
- Testing
- Birth Sisters Best Beginnings for Babies, Usual maternity care
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- Boston Medical Center
Preterm Labor
Intramuscular Hydroxyprogesterone Caproate and Placenta Previa
Antepartum hemorrhage is defined as bleeding from or within the female genital tract, occurring from 24+0 weeks of pregnancy and till delivery of the fetus.
- Trial name
- NCT03130504
- Testing
- 17α hydroxy progesterone caproate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Preterm Labor
Ultrasonographic Evaluation of Fetal Adrenal Gland in Cases of Threatened Preterm Labor
Preterm birth continues to be a major public health problem with lasting family and societal repercussions. Despite tremendous research effort, prevention strategies have failed, and the prevalence of preterm birth in the United…
- Trial name
- NCT03251794
- Testing
- three dimensional ultrasound, color Doppler
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Preterm Labor
Oral Versus Parental Progesterone in the Management of Preterm Labor
Preterm birth, defined as delivery at less than 37 weeks gestation, complicates approximately 12% of pregnancies in the United States Preterm delivery has been, and remains, the most important challenge to modern obstetrics.
- Trial name
- NCT03343795
- Testing
- oral progesterone, intramuscular progesterone
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
LABOR PAIN
Optimal Regimen of Patient-controlled Epidural Analgesia in Laboring Patients
To test the efficacy of different recipes of epidural infusions used for providing pain relief during labor in parturients.
- Trial name
- PCEA (NCT03566342)
- Volunteers
- 145 people
- Sponsor
- Maimonides Medical Center
Abnormal Labor, Failed Induction of Labor
Enhanced vs. Routine Clear Liquid Intake in Labor
The goal of the study is to see if the addition of a carbohydrate- and protein-enhanced gel during labor speeds labor and reduces the rate of cesarean delivery.
- Conditions
- Abnormal Labor, Failed Induction of Labor, Ketosis
- Trial name
- NCT02524002
- Testing
- Accel Gel, Usual clear diet
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Temple University
Preterm Labor
Different Types of Progesterone in the Prevention of Preterm Labor
Preterm birth is a common problem in obstetric care,with estimates ranging from 5% in several European countries to 18% in some African countries, Preterm labor defined as delivery before 37 completed weeks is the leading cause…
- Trial name
- NCT03537287
- Testing
- 17 alpha hydroxyprogestrone caproate, Vaginal progesterone, Oral dydrogesterone
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Acupuncture, Ear, Episiotomy; Complications
Auricular Acupuncture as Effective Pain Relief After Episiotomy
Background: Episiotomy is performed in up to 30% of vaginal deliveries. Previously, pain treatment following episiotomy has relied on non-steroid anti-inflammatory drugs (NSAID) as analgesics, whose use during breastfeeding…
- Conditions
- Acupuncture, Ear, Episiotomy; Complications, Pain, Labor
- Trial name
- NCT03534869
- Testing
- Ear acupuncture, Analgesics
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Prolonged Labor
Electronic Partograph: A Way of Improving Partograph Use During Labour Monitoring Process in Selected District Hospitals in Bangladesh
Background (brief): 1. Burden: Abnormal prolonged labour and its effects are important contributors to maternal and perinatal mortality and morbidity worldwide.
- Trial name
- NCT03509103
- Testing
- Electronic Partograph
- Volunteers
- 1,012 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Labor Pain
Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Epidural analgesia has proven to be an effective method for severe pain relief associated with labor and delivery. During labor, a low dose continuous infusion of local anesthetic and narcotic will be administered through an…
- Trial name
- NCT01846221
- Testing
- Clonidine, Fentanyl
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Columbia University
Fourth Degree Perineal Laceration Involving Anal Mucosa, Obstetric; Injury
Use of the Modified Beef Tongue Model for Teaching Repair of Obstetrical Fourth-Degree Laceration to Residents
This is a study evaluating the use of the modified beef tongue model for teaching repair of obstetrical fourth-degree laceration to residents.
- Conditions
- Fourth Degree Perineal Laceration Involving Anal Mucosa, Obstetric; Injury, Obstetric Labor Complications
- Trial name
- NCT03341351
- Testing
- Instructional video, Instructional workshop
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Labor
Oral Feeding During Established Labor at Our Institution
Current French guidelines allow oral intake of clear fluid in women in established labor under epidural analgesia. To date, no study assessed how these guidelines are followed in clinical practice.
- Trial name
- NCT03242356
- Testing
- Questionnaire to assess of the application of the current French guidelines as to fasting during labor.
- Where
- France
- Volunteers
- 195 people
- Sponsor
- Hospices Civils de Lyon
Labor Pain
Effect of LED Photobiomodulation on Analgesia During Labor
The aim of this study is to valuate the effects of LED photobiomodulation on analgesia during labor.ight-emitting diode (LED) photobiomodulation is an effective and noninvasive alternative to pharmacological methods.n total, 60…
- Trial name
- EPAL (NCT03496857)
- Testing
- Light emitting diode, Bath Therapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Obstetric Pain
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
During labor there is an increased production of inflammatory mediators called cytokines. Higher concentration of certain cytokines has been linked to adverse neonatal and maternal outcomes.
- Trial name
- NCT00361712
- Testing
- Preemptive epidural analgesia, Standard of care
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Labor Pain
Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
The study aims to determine whether the use of automated intermittent devices for labor analgesia could prevent the increase of instrumental deliveries, with same analgesia.
- Trial name
- PA-RER (NCT02710877)
- Testing
- Programmed Intermittent bolus, Manual epidural bolus, Levobupivacaine
- Where
- 3 sites in Italy
- Volunteers
- 671 people
- Sponsor
- University of Modena and Reggio Emilia
Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2
Cerclage for Twins With Short Cervix
A prospective randomized control trial that will compare cervical cerclage plus vaginal progesterone to vaginal progesterone along in twin pregnancies complicate by a short cervix (</= 15.0mm) between 16w0d to 25w6d.
- Conditions
- Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2, Cervical Incompetence, Cervical Shortening
- Trial name
- NCT03077633
- Testing
- Cervical Cerclage placement, Vaginal Progesterone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Aim is to Investigate Association Between Lactate Concentration in Vaginal Fluid and Time of Spontaneous Onset of Labor in PPROM
Best Cutoff Value of Lactate Concentration in Vaginal Fluid to Predict Time of Spontaneous Onset of Labor in PPROM
The present study is aimed to assess whether lactate determination in vaginal fluid is associated with and can predict onset of labor for women with suspected preterm prelabor rupture of membranes (PPROMs).
- Trial name
- NCT03463811
- Testing
- Lactate concentration in vaginal fluid
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mennatallah Mohamed Elnemr
Fetal Membranes, Premature Rupture
Myometrial Thickness as a Predictor for the Latency Interval in PPROM
100 women divided into 3 groups: Group I: included 50 women with preterm premature rupture of membranes (PPROM, n=50) with gestational age from 24 to 34 weeks.
- Trial name
- NCT02380560
- Testing
- Ultrasonographic examination
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor Induction, Third Trimester
Uterocervical Angle in Induction of Labor
To evaluate the performance of uterocervical angle (UCA) in the prediction of labor induction.
- Trial name
- NCT03308656
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital