Clinical trials: LGBTQ
Anxiety, Depression
Improving Mental Health Among the LGBTQ+ Community
The overall aim of this program of research is to improve the mental health of people who identify as LGBTQ+ by increasing their social support through a brief intervention.
- Trial name
- NCT05540067
- Testing
- Acceptance-Based Behavior Therapy (ABBT), Treatment-as-Usual (TAU)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Brown University
Emotion Regulation, Self Harm
Purrble With LGBTQ+ Youth Who Have Self-harmful Thoughts
The primary aim of the proposed Randomised Control study is to investigate the effects of a socially assisted robot (i.e. Purrble) on emotional regulation difficulties (measured by DERS8) with young LGBTQ+ people who have…
- Trial name
- NCT06025942
- Testing
- Purrble intervention
- Where
- United Kingdom
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- King's College London
Cancer Support, Oncology Patients
FOCUS ON US: Adapting the FOCUS Program for Sexual and Gender Minority (SGM) Cancer Patients and Caregivers
Our aim for this study is to assess the feasibility and acceptability and explore potential outcomes of the adapted FOCUS On Us intervention in a two-arm pilot trial.
- Conditions
- Cancer Support, Oncology Patients, Caregivers
- Trial name
- NCT06800053
- Testing
- FOCUS ON US
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles Kamen
Suicide, Self-Injurious Behavior
Youth Empowerment and Safety Intervention
This clinical trial will implement and evaluate the feasibility, acceptability, and initial impact of Peer Support Specialist (PSS) services for public system-involved sexual and gender minority (lesbian, gay, bisexual, queer…
- Trial name
- YES (NCT07214233)
- Testing
- Treatment as Usual, Peer Support Services (PSS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Case Western Reserve University
LGBTQ
Assessing Mental Health Providers' Clinical Knowledge and Skills Via an Online Training on LGBTQ-affirmative Cognitive-behavioral Therapy
The purpose of the proposed study is to train mental health providers (MHPs) at lesbian, gay, bisexual, transgender, and queer (LGBTQ) community centers across the United States in evidence-based, LGBTQ-affirmative…
- Trial name
- NCT04559698
- Testing
- LGBTQ-affirmative CBT training
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections
PrEP2Prevent An Online PrEP Navigation and Activation Intervention
The goal of this clinical trial entitled, PrEP2Prevent: An Online PrEP Navigation and Activation Intervention for YMSM, is to develop and test a method for supporting access to an HIV prevention medication called Pre-Exposure…
- Trial name
- P2P (NCT05281393)
- Testing
- PrEPresent
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Vaping, Adolescent Behavior
Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender Minority Teens
The investigators long-term goal is to reduce tobacco use and tobacco-related health disparities among SGM populations. The objective of Project SMART (Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender…
- Conditions
- Vaping, Adolescent Behavior, Communication Research
- Trial name
- SMART (NCT06308081)
- Testing
- Tailored
- Where
- United States
- Volunteers
- 1,155 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
HIV, Violence, Gender-Based
Supporting Trans Affirmation, Relationships, and Sex, Phase 3
The purpose of this clinical trial is to evaluate and test a newly developed gender-affirming intervention that addresses the dual and interconnected risks of HIV and intimate partner victimization (IPV) among transgender women…
- Conditions
- HIV, Violence, Gender-Based, Violence, Domestic, Risk Reduction Behavior
- Trial name
- STARS (NCT06001307)
- Testing
- Program STARS (Supporting Trans Affirmation, relationships, and Sex), Relaxation and Stress Reduction
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Brown University
CBT, LGBTQ
SGM Evidenced-Based Mental Healthcare Implementation
The purpose of the proposed study is to identify effective strategies for implementing lesbian, gay, bisexual, transgender, and queer (LGBTQ)- affirmative Cognitive-Behavioral Therapy (CBT) at LGBTQ community centers across the…
- Trial name
- NCT05890404
- Testing
- LGBTQ-Affirmative CBT Training: Materials Only, LGBTQ-Affirmative CBT Training: Direct Training, LGBTQ-Affirmative CBT Training: Local Supervision
- Where
- United States
- Volunteers
- 1,379 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
Empowering LGBTQ+ Tobacco Cessation Pilot
Sexual and/or gender minority (SGM) people have disproportionately high rates of tobacco use - the number one cause of preventable death.
- Trial name
- NCT05365633
- Testing
- Empowerment activity-enhanced tobacco cessation assistance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Lung Carcinoma
A Tailored Screening and Smoking Cessation Program for the LGBTQ Community of Seattle
This clinical trial develops a tailored screening and smoking cessation program for the lesbian, gay, bisexual, transgender (trans) and queer (LGBTQ) community of Seattle, Washington.
- Trial name
- NCT05304390
- Testing
- Patient Navigation, Questionnaire Administration, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Self-Harm, Suicidal
Co-Producing LGBTQ-Affirmative DBT Protocols.
Aims: 1. To co-produce new intervention parts that meet the needs of LGBTQ+ people at risk of self-harm or suicidal thoughts, with LGBTQ+ people and DBT therapists.
- Conditions
- Self-Harm, Suicidal, Emotional Dysregulation
- Trial name
- NCT06966193
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Cigarette Smoking
Culturally Targeted & Individually Tailored Smoking Cessation Study: LGBT Smokers
For the approximately 4.6 million LGBT persons in the U.S., smoking rates among those living in urban areas are roughly twice that of heterosexuals.
- Trial name
- NCT01633567
- Testing
- Culturally Targeted Cessation Program, Non-Targeted Cessation Program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Tobacco Use Disorder, Tobacco Use Cessation
TinCat LGBTQ+ Smoking Cessation Via Asynchronous Telehealth
The purpose of this study is to assess the efficacy of a novel telehealth-based intervention to reduce tobacco use among LGBTQ+ people.
- Trial name
- NCT05499364
- Testing
- TinCat, Quit.gov program
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Aggression, Adolescence
Wise Intervention for Reducing Aggressive Behaviors and Promoting Prosocial Behaviors Toward LGB-TNB Individuals
This study evaluates the effectiveness of a wise Intervention to reduce aggressive behaviors and promote prosocial behaviors toward LGB-TNB individuals among Spanish adolescents.
- Trial name
- LGB-TNB (NCT07212283)
- Testing
- Wise Intervention LGB-TNB, Values alignment wise intervention
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Heavy Drinking, Mental Health Issue
Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health
The purpose of this 2-arm randomized controlled trial is to assess the efficacy of a 10-session lesbian, gay, bisexual, transgender, and queer (LGBTQ)-affirmative cognitive-behavioral psychotherapy (CBT) delivered via telehealth…
- Trial name
- EQuIP (NCT05509166)
- Testing
- LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Yale University
Teen Pregnancy, STD Prevention
Evaluation of the Impact of the IN•Clued Curriculum: An LGBTQ Sex ed Program
The INclued program was implemented in 16 states across the US. The purpose of this study is to measure: Nine months after the end of the program and one year after the workshop, are IN•clued participants less likely to report…
- Trial name
- NCT04494477
- Testing
- The IN•clued program
- Where
- United States
- Volunteers
- 1,401 people, healthy volunteers welcome
- Sponsor
- Philliber Research & Evaluation
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Game Plan for PrEP
This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their…
- Trial name
- NCT04973267
- Testing
- Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Brown University
LGBTQ, Racial Disparities
Lakota Family Acceptance Project Pilot RCT
Although research documents the concerning rates of mental and behavioral health problems (e.g., substance use/initiation) among Indigenous LGBTQ2S+ youth, there is very little known about how to prevent these deleterious issues…
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP (NCT07865858)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Complex Post-Traumatic Stress Disorder, Post-traumatic Stress Disorder
Trauma-focused Psychodynamic Psychotherapy for LGBT Patients With Post-traumatic Stress Disorder
This is a pilot, open trial of trauma-focused psychodynamic psychotherapy for LGBT-identifying individuals who meet for DSM-5 defined post-traumatic stress disorder and are interested in receiving a research psychotherapy…
- Trial name
- NCT04532996
- Testing
- Trauma-focused psychodynamic psychotherapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Weill Medical College of Cornell University