Clinical trials: LET, open to volunteers
Lateral Epicondylitis, Elbow Tendinopathy
Upper Extremity-based Exercises and Elbow-focused Exercises in LET
The aim of the study is to investigate the effects of rotator cuff and scapular muscle strengthening exercises applied in addition to the 8-week elbow focused rehabilitation program in lateral elbow tendinopathy, by comparing it…
- Trial name
- NCT05809622
- Testing
- Elbow focused rehabilitation, Scapular and rotator cuff muscles strengthening
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul University - Cerrahpasa
ACL, LET
Outcomes and Complication Rates of Anterior Cruciate Ligament Reconstruction Using the "Over-the-top" Technique Combined With Lateral Extra-articular Tenodesis in Patients Over 50 Years Old, Compared With a Control Group of Patients Under 30
The anterior cruciate ligament (ACL) is one of the main stabilizers of the knee, and its injury is among the most common soft tissue injuries of the knee.
- Conditions
- ACL, LET, Hamstring Muscles
- Trial name
- ACL_50_YO (NCT07041242)
- Testing
- ligament reconstruction using the single-bundle "over-the-top" technique
- Where
- Italy
- Volunteers
- 164 people
- Sponsor
- Stefano Zaffagnini
Lactation Disorders
The Relationship Between Oxytocin Massage in Mothers With Insufficient Milk Production in the Early Postpartum Period and Breastfeeding Self-Efficacy and Milk Let-down Reflex: A Randomized Controlled Study
This randomized controlled trial aims to evaluate the effects of oxytocin massage on breastfeeding self-efficacy and the milk ejection reflex among mothers experiencing insufficient milk supply in the early postpartum period.
- Trial name
- NCT07609693
- Testing
- Oxytocin Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Anaplastic Ependymoma, Ependymoma
LET Optimized IMPT in Treating Pediatric Patients With Ependymoma
This phase I trial studies the side effects of linear energy transfer (LET) optimized image modulated proton therapy (IMPT) in treating pediatric patients with ependymoma.
- Trial name
- NCT03750513
- Testing
- Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- M.D. Anderson Cancer Center
Oral Submucous Fibrosis
Autologous PRP Versus Triamcinolone Acetate in Patients With Oral Submucous Fibrosis
Oral submucous fibrosis (OSF) is a chronic condition that causes stiffness of the oral tissues, reduced cheek flexibility, and difficulty opening the mouth.
- Trial name
- PRP OSF (NCT07914504)
- Testing
- Autologous Platelet-Rich Plasma, Triamcinolone Acetate
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Allama Iqbal Medical College
DNA, Cancer
Optimization of Radiation Protection Through Genomic Analyses
The long-term goal is to define "signatures" in the form of genomic changes through sequence analyses of genomic DNA using modern Next Generation Sequencing (NGS) methods, which 1. determine the radiation exposure of humans. 2.
- Conditions
- DNA, Cancer, Radiation
- Trial name
- ORtogether (NCT06253338)
- Testing
- genomic alterations
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Parent Training, Parent Child Relationship
Hold me Tight/Let me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship
HmT/LmG is a group course for 4-6 parental dyads and consists of 4 group sessions with psycho-education and skills training and 3 individual sessions per family (i.e., 1 session with the adolescent, 1 session with the parents…
- Conditions
- Parent Training, Parent Child Relationship, Parent-child Problem
- Trial name
- NCT06966323
- Testing
- Hold me Tight / Let me Go
- Where
- 5 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- University of Amsterdam
ACL, LET
Long-term Clinical and Radiographic Results of Revision Anterior Cruciate Ligament Reconstruction Using a Single-bundle Technique and External Tenodesis With Achilles Tendon Allograft.
Several techniques for revision of anterior cruciate ligament (ACL) reconstruction and different types of grafts have been used over the years.
- Trial name
- ACL_REVISION (NCT06868147)
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- Stefano Zaffagnini
Active tDCS, Sham tDCS
Combination of Neurostimulation and Psychotherapy to Stop Worrying
This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative thinking (RNT) in patients with…
- Trial name
- NCT06369532
- Testing
- Active tDCS
- Where
- Belgium
- Volunteers
- 85 people
- Sponsor
- University Hospital, Ghent
Fibromyalgia
LET for Fibromyalgia
The study is a double blinded, randomized, sham-controlled, parallel group trial conducted at UT Southwestern (UTSW) Medical Center.
- Trial name
- NCT07201818
- Testing
- Lymphatic Enhancement Technology (LET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
ACL Reconstruction, Tenodesis
Clinical and Biomechanical Outcomes of Anterior Cruciate Ligament (ACL) Reconstruction Associated With Lateral Extra-articular Tenodesis (LET)
The anterior cruciate ligament (ACL) is one of the main stabilizers of the knee joint, and its injury is among the most common soft tissue injuries of the knee.
- Conditions
- ACL Reconstruction, Tenodesis, ACL Injuries
- Trial name
- LETOTT (NCT07049484)
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Stefano Zaffagnini
Pancreatic Cancer Non-resectable
Ablative Carbon Ion Radiotherapy With Pencil Beam Scanning for Locally Advanced Unresectable Pancreatic Cancer
The aim of this study is to investigate the clinical efficacy and safety of ablative carbon ion radiotherapy for locally advanced unresectable pancreatic cancer with pencil beam scanning and simultaneous integrated boost (SIB)…
- Trial name
- NCT05424159
- Testing
- Carbon ion radiotherapy
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Shanghai Proton and Heavy Ion Center
Anterior Cruciate Ligament Injuries
ALL Reconstruction Versus Modified Lemaire's LET in Combination With ACL Reconstruction With a Minimum Follow up of 2 Years
Anterior cruciate ligament (ACL) tears are associated with concomitant lesions of the anterolateral ligament (ALL), which increase rotatory instability of the knee.
- Trial name
- ARAVET (NCT06147427)
- Testing
- ACL reconstruction with hamstrings combined with ALL plasty, ACL reconstruction with hamstrings combined with modified Lemaire's LET
- Where
- France
- Volunteers
- 248 people
- Sponsor
- Hospices Civils de Lyon
LET, ACL Reconstruction
Long-term Follow up of the Stability 1 Trial
From 2014-2017, across 7 Canadian and 2 European sites, we randomized 618 patients at high-risk of re-injury, to anterior cruciate ligament reconstruction (ACLR) with or without a lateral extraarticular tenodesis (LET) and…
- Conditions
- LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
- Trial name
- STABILITY LTF (NCT06885372)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Canada, United Kingdom
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Sepsis, Length of Stay
Limited Versus Extended Trophic Feeding (LET-FEED) Trial
Study Hypothesis/Question In infants born very preterm, advancing enteral feeds after 24 hours from birth (limited trophic feeds) versus after 72 hours (extended trophic feeds) reduces the risk of all-cause late onset sepsis…
- Conditions
- Sepsis, Length of Stay, Mortality, Neurodevelopmental Delay
- Trial name
- LET-FEED (NCT06893939)
- Testing
- Limited Trophic Feeds (1 day of trophic feeds), Extended Trophic Feeds (3 days of trophics)
- Where
- 6 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Washington
Tic Disorder, Provisional Tic Disorder
Let It TiC in Childhood Provisional Eye Tic
Clarify the effectiveness and safety of "Reduced-Attention Intervention Therapy" in treating children with Provisional tic disorder （PTD） who mainly exhibit abnormal blinking behavior
- Trial name
- LETITTIC (NCT07838428)
- Testing
- Reducing Attentional Interventions Therapy Treatment, Continue with the previous treatment plan
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Anterior Cruciate Ligament Reconstruction (ACLR)
The Effect of Lateral Extra-Articular Tenodesis on Lower-Extremity Lean Mass Recovery Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to determine whether the addition of Lateral Extra-Articular Tenodesis (LET) influences postoperative lower-extremity LM recovery following bone-patellar tendon-bone (BTB) Anterior Cruciate Ligament…
- Trial name
- NCT07777458
- Testing
- Bone-patellar Tendon-bone (BTB), Bone-patellar Tendon-bone (BTB) and Lateral Extra-Articular Tenodesis (LET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham