Clinical trials: L-PRF
Tooth Extraction, Alveolar Bone Loss
Autogenous Dentin Graft for Alveolar Ridge Preservatio
When a tooth is extracted, the bone around the empty socket naturally shrinks over time, which can make it difficult to place a dental implant later without additional bone-building procedures.
- Trial name
- ARF-PRF (NCT07789262)
- Testing
- Autogenous Dentin Graft, Platelet-Rich Fibrin (PRF), Freeze-Dried Bone Allograft (FDBA)
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Ankara Yildirim Beyazıt University
Tooth Extraction Site Healing
Efficacy of Albumin Platelet Rich Fibrin on Complications After Mandibular Third Molar Extraction.
Sixteen patients with bilateral impacted lower third molars seeking treatment will be recruited from the out-patient clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry at Mansoura University.
- Trial name
- NCT07153133
- Testing
- Alb-PRF Autologous Albumin Gel, Surgical extraction of impacted third molar
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Mansoura University
Vocal Cord Paralysis
Administration of Platelet-rich Fibrin to Autologous Fat Tissue in Injection Laryngoplasty for Vocal Cord Paralysis
The study tries to see the effect of using a combination of platelet-rich fibrin (PRF) and autologous fat as a filler for injection laryngoplasty procedures to treat unilateral adductor vocal cord paralysis.
- Trial name
- NCT04839276
- Testing
- Injection Laryngoplasty with Platelet-rich Fibrin and Autologous Fat, Injection Laryngoplasty with Autologous Fat
- Where
- Indonesia
- Volunteers
- 19 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Rotator Cuff, Tendon Injuries
Cascade PRFM Study: The Evaluation of Cascade Platelet-Rich Fibrin Matrix (PRFM) on Rotator Cuff Healing
Hypothesis: The use of cascade platelet-rich fibrin matrix (PRFM) on medium and large sized rotator cuff tears will improve patient results versus the control results by 50%.
- Trial name
- NCT00198185
- Testing
- Placement of Platelet Rich Fibrin Matrix During Arthroscopic Rotator Cuff Surgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Maxillary Sinus Disease
Biphasic Material With PRF in Lateral Sinus Floor Augmentation
A lack of bone in the posterior maxilla, mainly resulting from the combination of alveolar bone resorption after tooth loss, pneumatization of the maxillary sinus, and periodontal disease, leads to increased difficulty during…
- Trial name
- NCT06071416
- Testing
- Lateral sinus floor augmentation, Biphasic Calcium Phosphate, Injectable platlets rich fibrin
- Volunteers
- 18 people
- Sponsor
- Assiut University
Dupuytren's Contracture
Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound Healing
This study is a clinical, multicentric, randomised open trial. The objective is to evaluate the efficiency, in terms of wound healing speed, of peroperative application of autologous platelets gel versus standardized wound…
- Trial name
- NCT00931567
- Testing
- Autologous platelets gel, Vaselitulle
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Treatment of Periodontal Intra-bony Defects
The Present Study Was Performed to Evaluate the Efficacy of Lyophilized-PRF in Treatment of Periodontal Intra-bony Defects
The present study will be performed to evaluate the efficacy of lyophilized platelet-rich fibrin alone and combined with nanocrystalline hydroxyapatite in treatment of periodontal intra-bony defects through: 1.
- Trial name
- NCT06625528
- Testing
- open flap debridement
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Jaw Cysts
Volumetric Analysis of Bone Following Jaw Cysts Enucleation With and Without Alb-PRF
Cyst is the main cause for longstanding swelling in the mandible or the maxilla, its enlargement usually results in resorption and weakening of bone.
- Trial name
- NCT05658900
- Testing
- Enucleation with albumin PRF, Enucleation without albumin PRF
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Hams Hamed Abdelrahman
Gingival Recession
CGF and PRF in the Gingival Recessions Treatment
This study hypothesized that CGFs' placement together with CAF may enhance the healing of soft tissues better than use of PRF together with CAF.
- Trial name
- NCT04261634
- Testing
- Concentrated Growth Factor Membrane, Platelet Rich Fibrin
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Plantar Fasciitis
Bone Marrow Aspirate Versus Platelet-Rich Fibrin for the Treatment of Chronic Plantar Fasciitis
This randomized, double-blind clinical trial aims to compare the clinical and imaging effects of autologous bone marrow aspirate versus platelet-rich fibrin injections in patients with chronic plantar fasciitis.
- Trial name
- fasciitis (NCT07242729)
- Testing
- Bone Marrow Aspirate Injection, Platelet-Rich Fibrin Injection
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Federal University of São Paulo
Ridge Preservation
E-PRF vs Collagen Membranes in Ridge Preservation
Dental implants are often considered the gold standard to replace missing teeth. Having success with dental implants depends on the hard tissue and soft tissue remaining after tooth extractions.
- Trial name
- NCT07281053
- Testing
- Barrier membrane for ridge preservation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Center for Advanced Rejuvenation and Esthetics
Soft Tissue Augmentation
Clinical Evaluation of Soft Tissue Augmentation Using CTG and PRF Around Immediately Placed Dental Implants Versus Immediate Implant Alone in Esthetic Zone .
The main hypothesis to be certified is that the addition of Subepithelial Connective Tissue Graft (SCTG) and Platelet rich Fibrin (PRF) to immediately placed implants will not significantly differ from immediately placed implant…
- Trial name
- NCT03413553
- Testing
- immediate implant, connective tissue graft, platelet rich fibrin
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Abeer hassan sharafuddin
Pulp Necroses
Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth
The aim of the present study is to assess clinically and radio-graphically the regenerative potential of immature permanent teeth with necrotic pulp using blood clot and Platelet rich fibrin scaffolds.
- Trial name
- NCT04390854
- Testing
- Blood clot scaffold, Blood clot scaffold combined with PRF
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nourhan M.Aly
Thin Gingival Biotype
Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival Phenotype
The goal is to compare between the effect of vitamin C and Injectable-platelet rich fibrin in the management of thin gingival phenotype.
- Trial name
- NCT05841303
- Testing
- Vit C, injectable PRF
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cairo University
Platelet-Rich Fibrin, Dental Implantation
Influence of Human Platelet Derivatives on Dental Implant
The goal of this randomized controlled trial is to evaluate the benefit of PRF membrane on bone around dental implant in patients who need treatment with dental implant.
- Conditions
- Platelet-Rich Fibrin, Dental Implantation, Bone Substitute
- Trial name
- NCT06044246
- Testing
- PRF membrane
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Anterior Cruciate Ligament Injury, Knee Injuries
Sensory Deficit Following ACL Reconstruction: PRF Pilot Study
Pilot, single-center, non-randomized, parallel-group clinical study designed to assess whether intraoperative application of autologous platelet-rich fibrin (PRF) at the bone-patellar tendon-bone (BPTB) donor site reduces…
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injuries, Sensory Disorders, Bone-Patellar Tendon-Bone Autograft
- Trial name
- PRF-ACL (NCT07257666)
- Testing
- Platelet-rich fibrin (PRF), Standard Closure (Control)
- Where
- Serbia
- Volunteers
- 53 people
- Sponsor
- University of Belgrade
Alveolar Osteitis
Use of PRF in Treatment of Dry Socket.
The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.
- Trial name
- NCT04476121
- Testing
- PRF application, Nipas application
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Effect of Platelet Rich Fibrin Versus Microosteoperforation Compaed to Control Group Toothmovement
Assessment of the Efficacy of Microosteoperforations Versus Injectable Platelet-rich Fibrin During Orthodontic Leveling and Alignment of Mandibular Incisors
The aim of this prospective clinical study will be to compare the efficacy of micro osteoperforations versus injectable platelet-rich fibrin during orthodontic leveling and alignment of mandibular incisors.
- Trial name
- NCT06498609
- Testing
- iprf, MOPs with leveling and alignment
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Endodontic Inflammation
Regenerative Endodontic Procedure of Immature Permanent Teeth With L-PRF: a Pilot Controlled, Clinical Trial
This study evaluates the impact of autologous 'leucocyte and platelet rich fibrin' (L-PRF) on the periapical bone healing and further root development of infected immature permanent teeth.
- Trial name
- NCT02437708
- Testing
- REP with L-PRF, REP, stem and progenitor cells
- Where
- 4 sites in Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Wound Heal
The Effects Of I-PRF On Gingivectomy and Gingivoplasty
The study aims to evaluate the effects of injectable platelet-rich fibrin (I-PRF) applications on early wound healing after gingivectomy and gingivoplasty surgery.
- Trial name
- NCT05871190
- Testing
- İnjectable platelet rich fibrin, Gingivectomy anad gingivoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi