Clinical trials: L-PRF
Lower Extremity, Chronic Ulcers
Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Lower Extremity Ulcers
To prospectively evaluate the safety and efficacy of an Autologous Platelet-Rich Fibrin Plasma system when applied in conjunction with Standard of Care for management of chronic lower extremity wounds.
- Conditions
- Lower Extremity, Chronic Ulcers, Pressure Ulcer (PU), Venous Leg Ulcer (VLU)
- Trial name
- NCT07862335
- Testing
- PRFM
- Volunteers
- 30 people
- Sponsor
- Tiger Biosciences, LLC.
Diabetic Foot Ulcer (DFU), Ulcer
Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Diabetic Foot Ulcers
To prospectively evaluate the safety and efficacy of an Autologous Platelet-Rich Fibrin Plasma system when applied in conjunction with Standard of Care for management of chronic Diabetic Foot Ulcers.
- Conditions
- Diabetic Foot Ulcer (DFU), Ulcer, Wound Closure, Wound Management
- Trial name
- NCT07840378
- Testing
- PRFM, Standard of Care (SoC)
- Volunteers
- 55 people
- Sponsor
- Tiger Biosciences, LLC.
Wound Chronic Draining, Wound Closure
Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds
Platelet-based therapies have been used to treat bony and soft tissue effects for more than 30 years. Tropocells® Autologous Platelet-Rich Fibrin (PRF) is being used to treat chronic, non-healing wounds, of a variety of types.
- Trial name
- NCT07318792
- Testing
- Platelet-rich fibrin (PRF)
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Estar Medical dba Medical Technologies, LTD
Oral Surgical Procedures
Plenum® Osshp in Maxillary Sinus Elevation Surgery
The aim of this study is to qualitatively and quantitatively evaluate bone neoformation in maxillary sinus lift surgery filled with Plenum® Oss hp, compared to filling with autogenous bone, and to verify the association of…
- Trial name
- NCT06136143
- Testing
- Group 1: Autogenous bone graft, Group 2: Plenum® Osshp, Group 3: Plenum® Osshp; + i-PRF
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- M3 Health
Stress Urinary Incontinence
Platelet-rich Fibrin Versus HIFU in Management of Stress Urinary Incontinence
Aim of the study is to compare effect of High Intensity Focused Ultrasound (HIFU) and platelet-rich fibrin in management of stress urinary incontinence. It is a randomized prospective study.
- Trial name
- NCT04144829
- Testing
- HIFU, Fibrin
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Intima Clinic
Diabetic Foot Ulcers
Evaluation of the Effect of Vivostat Platelet Rich Fibrin(PRF) in the Treatment of Diabetic Foot Ulcers
Diabetic foot ulcers are a challenge to health care professionals because there are only few effective topical therapeutic interventions.
- Trial name
- NCT00770939
- Testing
- Vivostat PRF
- Where
- 5 sites in Denmark, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Vivostat
Anastomotic Leak Rectum
Investigation of the Benefit of Using an Autologous Platelet-rich Fibrin Matrix (Obsidian ASG®) for Treatment of Anastomosis During Rectal Surgery
Anastomotic insufficiency remains one of the most significant problems after rectal resection.The complications following anastomotic insufficiency leads to increased morbidity and mortality with subsequent prolongation of…
- Trial name
- ORSY (NCT05174910)
- Testing
- Obsidian ASG
- Where
- 13 sites in Austria, Germany and 3 more
- Volunteers
- 250 people
- Sponsor
- Vivostat
Diabetic Foot Ulcer, Type 1 Diabetes Mellitus
Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.
The goal of this investigational study is to evaluate the safety and clinical performance of Tropocells Autologous Platelet-rich Fibrin (PRF) for wound care for both males and females, ages 18-80 years old, with Grade 1 and 2…
- Conditions
- Diabetic Foot Ulcer, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM), Neuroischemic Foot Ulcer
- Trial name
- NCT06810726
- Testing
- Platelet Rich Plasma
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Estar Medical dba Medical Technologies, LTD