Clinical trials: Knowledge Translation
Heart Failure
VIrtual Care To Improve Outcomes and RecoverY From Heart Failure Hospitalization
The clinic visits (intervention) will continue for 90 days, which represents the follow-up period for the primary medication and health status outcomes. The co-primary clinical outcomes will be obtained at 180 days.
- Trial name
- VICTORY-HF (NCT05724433)
- Testing
- Virtual HF Care, Routine HF Care
- Where
- 9 sites in Canada, Tunisia
- Volunteers
- 891 people
- Sponsor
- Population Health Research Institute
Chronic Kidney Disease
A Cluster Randomized Trial to Assess the Impact of Patient and Provider Education on Use of Home Dialysis
Patients with severe kidney failure require dialysis or transplantation to survive. For those in whom a transplant is not an option, there are two main dialysis options: hemodialysis (either incenter or at home) or home…
- Trial name
- NCT02202018
- Testing
- Active KT intervention
- Where
- 2 sites in Canada
- Volunteers
- 55 people
- Sponsor
- University of Calgary
Cancer
Evaluating the Impact of the McMaster Optimal Aging Portal on Cancer Prevention Behaviours in Underserved Populations
The goal of the McMaster Optimal Aging Portal is to be a trustworthy source for health information. The Portal team can see (through measuring analytics of website use) that thousands of people are using the Portal and the…
- Trial name
- NCT03186703
- Testing
- Tailored knowledge translation
- Where
- Canada
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiac Arrest
The Strategies for Post Arrest Resuscitation and Care Network
Background: One of the 2010 Impact Goals of the Emergency Cardiac Care (ECC) Committee of the American Heart Association is to double survival from cardiac arrest.
- Trial name
- SPARC (NCT00683683)
- Testing
- Knowledge Translation
- Volunteers
- 32 people
- Sponsor
- Unity Health Toronto
Smoking Cessation
Integrating Smoking Cessation Into Routine Primary Care Practice
The aim of this study is to determine if providing smokers identified in family doctors offices with follow-up counselling enhances their success with quitting and the number of health professionals helping patients with…
- Trial name
- NCT00799279
- Testing
- Smoking cessation training, support, and telephone follow-up, smoking cessation intervention
- Volunteers
- 835 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Pain
A Randomized Trial Comparing "Push" Versus "Pull" Technology for Mobilizing Pain Evidence Into Practice Across Different Health Professions
Pain is a problem for many Canadians. Unfortunately, many doctors, nurses, therapists, and psychologists have trouble keeping up to date and applying the latest research that might help patients suffering with pain.
- Trial name
- NCT01348802
- Testing
- Push + Pull, Pull
- Where
- Canada
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- McMaster University
Osteoporosis, Wrist Fractures
Controlled Trial to Increase Detection and Treatment of Osteoporosis in Older Patients With a Wrist Fracture
The primary objective of this proposed research is to improve the quality of care for patients who present to the Emergency Department with osteoporosis and a fracture of the wrist, by increasing the use of proven efficacious…
- Trial name
- NCT00175214
- Testing
- Multifaceted intervention (patient education, physician guidelines, reminders)
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Alberta
Chronic Diseases
A Cluster-randomized Controlled Knowledge Translation Feasibility Study in Alberta Community Pharmacies
Background: Despite evidence of benefit for pharmacist involvement in chronic disease management, the provision of these services in community pharmacy has been suboptimal.
- Trial name
- NCT02191111
- Testing
- Task-focused facilitation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Atrial Fibrillation
RELY-ABLE Long Term Multi-center Extension of Dabigatran Treatment in Patients With Atrial Fibrillation Who Completed RE-LY Trial
The purposes of this study are: 1. To evaluate the long-term safety of dabigatran etexilate 2. To assess the effect of a knowledge translation intervention on patient outcomes
- Trial name
- NCT00808067
- Testing
- dabigatran dose 1, dabigatran dose 2
- Where
- 567 sites in United States, Australia and 33 more
- Volunteers
- 5,897 people
- Sponsor
- Boehringer Ingelheim
Physicians Evidence Retrieval Skills
Multifaceted Online Interventions to Increase Clinicians Searching of Current Best Evidence to Answer Clinical Questions
Translation of new knowledge from research into evidence-informed health care is a shared obligation of the clinical and the scientific communities.
- Trial name
- MPFS (NCT02038439)
- Testing
- Intervention A - Online Clinical Questions Recorder, Intervention B - Online Evidence Retrieval Coach, Intervention C - Online Audit and Feedback
- Where
- Canada
- Volunteers
- 908 people
- Sponsor
- McMaster University
Healthy Volunteer
OrthoEvidence Trial Assessing Japanese Knowledge Updates
The purpose of this randomized controlled trial is to clarify whether providing translated evidence summary (Advanced Clinical Evidence (ACE) reports from OrthoEvidence) will increase the access to the summary compared to…
- Trial name
- OTAKU (NCT05250622)
- Testing
- Japanese-translated evidence summaries (Advanced Clinical Evidence report from OrthoEvidence), English evidence summaries (Advanced Clinical Evidence report from OrthoEvidence)
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- McMaster University
Osteoarthritis, Knee, Meniscus; Degeneration
Knowledge Translation and Exercise for Degenerative Meniscal Tears and Early Osteoarthritis: KNEE-DEeP Study
Knee pain due to a degenerative meniscal tear (DMT) or early osteoarthritis (OA) is a frequent presentation in middle-aged and older adults.
- Trial name
- KNEE-DEeP (NCT06576557)
- Testing
- KNEE-DEeP intervention- Knowledge translation and exercise for early degenerative knee pain
- Where
- Ireland
- Volunteers
- 36 people
- Sponsor
- University of Limerick
Brain Hypoxia Ischemia
Continuous, Non-invasive Monitoring of Intraoperative Cerebral Perfusion and Oxidative Metabolism (CPOM)
This study uses a CPOM Optical neuromonitor to assess the relationship between brain cytochrome C oxidase, cerebral oxygen saturation and blood pressure during surgery performed under general anesthesia.
- Trial name
- NCT03907904
- Testing
- CPOM Optical Neuromonitor
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Western University, Canada
Acute Gastroenteritis, Pediatric ALL
Evaluating a Knowledge Translation Tool for Parents
Diarrhea and vomiting in children is a common reason to visit the emergency department. There has been a lot of research on how best to treat children with diarrhea and vomiting who visit the emergency department; however, the…
- Conditions
- Acute Gastroenteritis, Pediatric ALL, Knowledge Translation
- Trial name
- NCT03234777
- Testing
- Whiteboard animation video, Regular video
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Stroke
Building Capacity in the System to Support Persons With Stroke and Cognitive Impairment
Patients with cognitive impairments following a stroke are often denied access to inpatient rehabilitation, despite evidence of its benefits for them.
- Trial name
- CO-OP_KT (NCT02597569)
- Testing
- CO-OP KT Exposure
- Where
- 5 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Low Back Pain, Knowledge, Attitudes, Practice
Measurement Properties of the Turkish Version of the Low Back Pain Knowledge Questionnaire
This study aims to assess the validity and reliability of the Turkish version of the Low Back Pain Knowledge Questionnaire (LKQ).
- Trial name
- LKQ (NCT06911164)
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people
- Sponsor
- Ordu University
Back Pain, Knowledge
Turkish Version of Back Pain Knowledge and Beliefs Survey
Low back pain (LBP) is a globally prevalent health issue, affecting the majority of individuals at some point in their lives. Misconceptions about LBP can prolong its chronicity, highlighting the importance of educating patients…
- Conditions
- Back Pain, Knowledge, Beliefs, Translation, Cultural Adaptation and Turkish Validation
- Trial name
- BacKS-tr (NCT06780800)
- Testing
- The Back Belief Questionnaire Tr (BBQ) and Backs-tr, Backs-tr retest
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ordu University
Asthma, Chronic Obstructive Pulmonary Disease
Asthma & COPD Guideline Implementation
This is a report of a protocol developed to improve asthma and COPD care in a primary care setting. The study was approved by an Ethics Committee and support by the Canadian Thoracic Society through an unrestrictive grant from…
- Trial name
- NCT01766544
- Testing
- Standard Practice Group (SPG), TISG
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Laval University
Pain
Sustainability of a Knowledge Translation Intervention to Improve Paediatric Pain
The purpose of this research study is to evaluate the effectiveness of short refresher sessions. "Pain Practice Change Boosters" given at regular intervals to sustain improved pain process (assessment and management) and clinical…
- Trial name
- NCT02236949
- Testing
- Pain Practice Change Booster Intervention
- Where
- 7 sites in Canada
- Volunteers
- 3,907 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Knowledge Translation, Cognitive Impairment
Preventing and Managing Cognitive Impairment
This randomized controlled trial (RCT) is used to address the knowledge translation of primary care practitioners (PCPs) for the early identification of cognitive impairment.
- Trial name
- CognitnECHO (NCT05471141)
- Testing
- Cognition ECHO
- Sponsor
- Charles Drew University of Medicine and Science