Clinical trials: Knee Osteoarthristis, open to volunteers
Rehabilitation, Excercise
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis.
- Conditions
- Rehabilitation, Excercise, Geriatric, Physical Therapy
- Trial name
- 5Ms/PT/KOA/OA (NCT07640529)
- Testing
- Geriatric 5Ms framework, Exercises PT
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University
Knee Osteoarthristis, ACL Injuries
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA).
- Conditions
- Knee Osteoarthristis, ACL Injuries, Post-Traumatic
- Trial name
- PTOA Knee (NCT06686680)
- Testing
- extracorporeal shockwave therapy (ESWT)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Spaulding Rehabilitation Hospital
Knee Osteoarthristis
Neuropathic Pain in Knee Osteoarthritis: Pain Severity and Functional Status
Osteoarthritis (OA) is a degenerative joint disease characterized by structural changes such as cartilage loss and osteophyte formation, leading to functional limitations and disability.
- Trial name
- NCT07367126
- Testing
- Clinical and Functional Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Knee Osteoarthristis
Integrative Chinese and Western Medicine for Knee Osteoarthritis
This study aims to investigate if an integrated approach combining Traditional Chinese and Western medicine can better treat knee osteoarthritis.
- Trial name
- NCT07072442
- Testing
- Western Medicine, herbal medicine and acupuncture, herbal medicine
- Volunteers
- 228 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Osteoarthristis
Mobile App Use for Physical Activity in Knee Osteoarthritis
The goal of this clinical trial is to evaluate the effectiveness of an app developed to provide useful guidance on physical activity for people with knee osteoarthritis.The main question it aims to answer is: "What physical…
- Trial name
- moveforknee (NCT06721208)
- Testing
- use the "Move for Knee" APP
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Central Sensitization, Knee Osteoarthristis
Aquatic Exercise in Patients With Knee Osteoarthritis
The effect of aquatic exercise on central sensitization in patients with knee osteoarthritis are not fully known in the studies conducted to date.
- Conditions
- Central Sensitization, Knee Osteoarthristis, Aquatic
- Trial name
- NCT07883824
- Testing
- Standard physical therapy, Hydrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Knee Osteoarthristis, Total Knee Anthroplasty
Prospective, In-Vivo, Post-Market Safety and Efficacy Surveillance Registry of the MAXX Orthopedics, Freedom Total Knee® System
In an effort to satisfy regulatory requirements for post-market surveillance of product safety and efficacy, a representative sample of patients will be recruited for prospective monitoring.
- Trial name
- NCT06627699
- Testing
- Total Knee Arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Maxx Orthopedics Inc
Knee Osteoarthristis
Effect of Knee and Heel Off-Loader Brace With Non Weight Bearing Strength in Knee Osteoarthritis
The current study is a single-blinded, parallel-group pilot randomized controlled trial involving 20 participants diagnosed with knee osteoarthritis (KOA).
- Trial name
- NCT07562685
- Testing
- Knee and Heel Off-Loader Brace with NWB Strength Training, Conventional Knee Off-Loader Brace with NWB Strength Training
- Volunteers
- 20 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Knee Osteoarthristis, Hyaluronic Acid
The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis
HA therapy typically consists of several intra-articular injections administered at weekly intervals. A single-dose IA-HA treatment offers patients and physicians a treatment option that involves both lower costs and fewer clinic…
- Trial name
- ESSDHAITKO (NCT07487038)
- Testing
- Intra-articular hyaluronic acid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Knee Osteoarthristis
Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis
Knee osteoarthritis (OA) affects an estimated 654 million people over age 40 world-wide. In the United States, approximately 16% of adults over the age of 40 have knee OA.
- Trial name
- NCT07652437
- Testing
- Dephy Exoboot
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Joint Osteoarthritis, Knee Osteoarthristis
Clinical Evaluation of TrHCROSS® for Different Joints
This post-market clinical investigation is designed to evaluate the safety and effectiveness of TrHCROSS®, a CE-marked cross-linked hyaluronic acid viscosupplement, in patients with mild to moderate osteoarthritis of the knee…
- Conditions
- Joint Osteoarthritis, Knee Osteoarthristis, Hip Ostearthritis, Shoulder Osteoarthritis
- Trial name
- NCT07870031
- Testing
- TrHCROSS®, Monovisc
- Volunteers
- 150 people
- Sponsor
- i+Med S.Coop.
Knee Osteoarthristis
Study NRPT Feasibility in Knee Osteoarthritis
To Evaluate Feasibility and Exploratory Clinical and Biomarker Signals of NRPT in Adults with Knee Osteoarthritis
- Trial name
- NRPT (NCT07917403)
- Testing
- NRPT
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Knee Osteoarthristis, Arthroplasties, Knee Replacement
Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty
The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to…
- Trial name
- NCT07319546
- Testing
- Accelerated exercise, Routine exercise
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Knee Osteoarthristis, Knee Pain Arthritis
Stimulation of Peripheral Afferents to Reduce Muscle Inhibition at the Knee
Knee osteoarthritis is a leading cause of disability, and the muscle weakness that limits walking in this population arises not only from the joint itself but from afferent signals that inhibit motor drive to the thigh muscle…
- Conditions
- Knee Osteoarthristis, Knee Pain Arthritis, Knee Pain Chronic
- Trial name
- SPARK (NCT07832669)
- Testing
- Peripheral Electrical Stimulation (PES), Paired Pulse Electrical Stimulation (ppES)
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Knee Osteoarthristis, Diabetes (DM)
The NTU JO-SMART Study
This study recruits patients with coexisting obesity and knee osteoarthritis (KOA) to implement the NTU-JO Smart Program, an innovative intervention integrating AI-assisted community-based exercise with continuous glucose…
- Conditions
- Knee Osteoarthristis, Diabetes (DM), Obesity & Overweight, Chronic Kidney Disease
- Trial name
- NCT07317310
- Testing
- NTU-JO Smart Program
- Where
- 2 sites in Taiwan
- Volunteers
- 312 people
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthristis
geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older…
- Trial name
- RAMBO (NCT07380906)
- Testing
- Genicular Artery Embolization
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Joint & Vascular Institute
Knee Osteoarthristis
The Validity and Reliability of the OMERACT in the Turkish Population
Knee osteoarthritis is a chronic disease common in middle-aged and older adults, characterized by functional impairment and reduced quality of life due to pain.
- Trial name
- NCT07416357
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Democracy University
Knee Osteoarthristis
Close Chain and Open Chain Exercises With Blood Flow Restriction in Knee Osteoarthritis
The aim of this research is to find and compare the effect of close chain and open chain exercises with blood flow restriction in knee osteoarthritis on pain, range of motion, strength and functional performance in patients with…
- Trial name
- NCT07426549
- Testing
- Closed kinetic chain exercises with blood flow restriction, Open kinetic chain exercises with blood flow restriction
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Knee Osteoarthristis
Precision Rehabilitation: Mechanisms and Efficacy of Vibration in Exercise Training for Degenerative Knee Osteoarthritis
Knee osteoarthritis (OA) is a common degenerative disease in older populations. Chronic pain, quadriceps weakness, limited daily activities, lack of mobility, and balance and walking dysfunction are the most common symptoms.
- Trial name
- NCT06616896
- Testing
- vibration
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthristis, Meniscus Injury
Hemi-tibial Plateau Osteotomy Combined With Arthroscopic Repair for Medial Meniscus Posterior Root Tears in Varus Knees
This is a single-center clinical trial started by the study team. The goal is to compare two surgeries for people who have a varus knee alignment and a tear at the back attachment of the medial meniscus.
- Trial name
- NCT07356674
- Testing
- Hemi-tibial plateau osteotomy combined with arthroscopic repair, High tibial osteotomy combined with arthroscopic repair
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University